Loss of adipocyte-type fatty acid binding protein and other protein biomarkers is associated with progression of human bladder transitional cell carcinomas

Cancer Research

Volumn 56, Issue 20, 1996, Pages 4782-4790

  Celis, Julio E ^a   Østergaard, Morten ^a   Basse, Bodil ^a   Celis, Ariana ^a   Lauridsen, Jette B ^a   Ratz, Gitte P ^a   Andersen, Inger ^a   Hein, Bente ^b   Wolf, Hans ^b   Ørntoft, Torben F ^b   Rasmussen, Hanne Holm ^a  

^a AARHUS UNIVERSITY   (Denmark)

^b AARHUS UNIVERSITY HOSPITAL   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

FATTY ACID BINDING PROTEIN;

ARTICLE; BLADDER CARCINOGENESIS; CANCER GRADING; CORRELATION FUNCTION; HUMAN; HUMAN TISSUE; PRIORITY JOURNAL; PROTEIN EXPRESSION; TRANSITIONAL CELL CARCINOMA; UROTHELIUM;

CARCINOMA, TRANSITIONAL CELL; CARRIER PROTEINS; DISEASE PROGRESSION; FATTY ACID-BINDING PROTEINS; HUMANS; MYELIN P2 PROTEIN; NEOPLASM PROTEINS; PHENOTYPE; TUMOR MARKERS, BIOLOGICAL; TUMOR SUPPRESSOR PROTEINS; URINARY BLADDER; URINARY BLADDER NEOPLASMS;

EID: 10144222646     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (54)

1. Friedell, G H , Nagy, G. K , and Cohen, S. M. Pathology of human bladder cancer and related lesions. In. G T Bryan and S. M. Cohen (eds.), The Pathology of Bladder Cancer, Vol. 1, pp 11-42 Boca Raton, FL. CRC Press, Inc , 1983
2. Pauli, B. U., Alroy, J., and Weinstein, R. S. The ultrastructure and pathobiology of unnary bladder cancer. In G T. Bryan and S. M. Cohen (eds.), The Pathology of Bladder Cancer, Vol. II, pp. 41-140. Boca Raton, FL: CRC Press, Inc., 1983.
3. Mostofi, F. K., Davis, C. J , Jr, and Sesterhenn, I. A. Current understanding of pathology of bladder cancer and attendant problems. J. Occup. Med., 32: 793-796, 1990.
4. Heney, N M, Ahmed, S., Flanagar, M J., Frable, W., Corder, M. P., Hafermann, M. D., and Hawkins. I. R. Superficial bladder cancer: progression and recurrence. J. Urol., 130: 1083-1086, 1983.
5. Slaughter, D. P , Southwick, H. W., and Smejkal, W "Field cancerization" in oral stratified squamous epithelium Cancer (Phila), 6. 963-968, 1953.
6. Witjes, J A., Kiemeney, L A., Oosterhof, G O., and Debruyne, F. M. J. Prognostic factors in superficial bladder cancer. A review. Eur. Urol., 21: 89-97, 1992.
7. Vogelstein, B , Fearon, E. R., Hamilton, S. R. Kern, S. E., Preisinger, A. C., Leppert, M , Nakamura, Y , White, R Smits, A M., and Bos, J. L. Genetic alterations during colorectal-tumor development. N. Engl J Med., 319: 525-532, 1988
8. Simoneau, A R., and Jones, P. A. Bladder cancer: the molecular progression to invasive disease World J. Urol., 12: 89-95, 1994.
9. Sidransky, D, and Messing, E. Molecular genetics and biochemical mechanisms in bladder cancer. Oncogenes, tumor suppressor genes and growth factors. Urol. Clin. North Am , 19: 629-639, 1992
10. Sandberg, A. A Chromosome changes in early bladder neoplasms J. Cell. Biochem., 161 (Suppl.): 76-79, 1992.
11. Penicca, D., Szepetowski, P , Simon, M P., and Gaudray, P. Molecular genetics of human bladder carcinomas. Cancer Genet. Cytogenet., 49, 143-156, 1990.
12. Presti, J. C., Jr., Reuter, V. E., Galan, T., Fair, W R, and Cordon-Cardo, C. Molecular genetic alterations in superficial and locally advanced human bladder cancer. Cancer Res., 51: 5405-5409, 1991.
13. Sidransky, D., Von Eschenbach, A., Tsai, Y. C., Jones, P., Summerhayes, I., Marshall, F., Paul, M., Green, P , Hamilton, S. R., Frost, P., and Vogelstein, B. Identification of p53 gene mutations in bladder cancers and urine samples. Science (Washington DC), 252: 706-709, 1991.
14. Spruck, C H., III, Ohneseit, P. F., Gonzalez-Zulueta, M., Esrig, D., Miyao, N , Tsai, Y C., Lerner, S. P , Schmütte, C., Yang, A. S , Cote, R., Dubeau, L., Nichols, P W., Hermann, G. G., Steven, K , Horn, T., Skinner, D. G., and Jones, P. A. Two molecular pathways to transitional cell carcinoma of the bladder. Cancer Res., 54: 784-788, 1994.
15. Moll, R. Molecular diversity of cytokeratins. significance for cell and tumor differentiation Acta Histochem. (Suppl.), 41: 117-127, 1991.
16. Mulder, A. H., Van Hootegem, J. C., Sylvester, R., ten Kate, F J., Kurth, K. H., Ooms, E C., and Van der Kwast, T. H. Prognostic factors in bladder carcinoma: histologic parameters and expression of a cell cycle-related nuclear antigen (Ki-67). J. Pathol., 166: 37-43, 1992
17. Vet, J. A., Debruyne, F M., and Schalken, J. A. Molecular prognostic factors in bladder cancer. World J. Urol , 12: 84-88, 1994.
18. Ørntoft, T. F. Carbohydrate changes in bladder carcinomas. APMIS 27 (Suppl.): 181-187, 1992.
19. Celis, J. E., Rasmussen, H. H., Vorum, H., Madsen, P , Honoré, B., Wolf, H., and Ørntoft, T. F. Bladder squamous cell carcinomas (SCCs) express psoriasin and externalize it to the urine J. Urol, 155 2105-2112, 1996.
20. Celis, J. E., Rasmussen, H H., Gromov, P., Olsen, E., Madsen, P., Leffers, H., Honoré, B., Dejgaard, K., Vorum, H., Back Christensen, D , Østergaard, M., Haunsø, A , Aagaard Jensen, N , Celis, A , Basse, B , Laundsen, J. B , Ratz, G. P , Andersen, A H., Walbum, E., Kjærgaard, I., Andersen, I , Puype, M., Van Damme, J., and Vandekerckhove, J. The human keratinocyte two-dimensional protein database (update 1995). mapping components of signal transduction pathways. Electrophoresis, 16: 2177-2240, 1995.
21. Rasmussen, H. H , Ømtoft, T. F., Wolf, H., and Celis, J. E Towards a comprehensive database of proteins from the urine of patients with bladder cancer. J. Urol., 155: 2113-2119, 1996
22. Madsen, P., Rasmussen, H. H , Leffers, H., Honoré, B., Dejgaard K , Olsen, E., Kill, J., Walbum, E., Andersen, A. H. Basse, B., Laundsen, J. B., Ratz, G. P , Celis, A., Vandekerckhove, J., and Celis, J. E. Molecular cloning, occurrence and expression of a novel partially secreted protein "psoriasin" that is highly up-regulated in psoriatic skin. J. Invest. Dermatol, 97: 701-712, 1991
23. O'Farrell, P. H. High resolution two-dimensional gel electrophoresis. J. Biol. Chem., 250: 4007-4021, 1975
24. Celis, J. E., Ratz, G , Basse, B., Lauridsen, J B, and Celis, A. High-resolution two-dimensional gel electrophoresis of proteins: isoelectric focusing and nonequilibnum pH gradient electrophoresis (NEPHGE). In J. E. Celis (ed.),. Cell Biology: A Laboratory Handbook, Vol 3. pp 222-230. San Diego: Academic Press, Inc., 1994
25. Celis, J E., Laundsen, J. B., and Basse, B. Determination of antibody specificity by western blotting and immunoprecipitation. In: J. E. Celis (ed.), Cell Biology: A Laboratory Handbook, Vol. 2, pp. 305-313. San Diego: Academic Press, Inc., 1994.
26. Vandekerckhove, J., and Rasmussen, H. H. Internal amino acid sequencing of proteins recovered from one- or two-dimensional gels. In: J. E. Celis (ed.), Cell Biology A Laboratory Handbook, Vol. 3, pp. 359-368. San Diego: Academic Press, Inc , 1994
27. Rasmussen, H. H., Mortz, E., Mann, M., Roepstorff, P., and Celis, J E. Identification of transformation sensitive proteins recorded in human two-dimensional gel protein databases by mass spectrometric peptide mapping alone and in combination with microsequencing Elecirophoresis, 15: 406-416, 1994
28. Leffers, H , Madsen, P., Rasmussen, H. H , Honoré, B., Andersen, A. H., Walbum, E., Vandekerckhove, J , and Celis, J. E Molecular cloning and expression of the transformation sensitive epithelial marker stratifin. A member of a protein family that has been involved in the protein kinase C signalling pathway. J. Mol. Biol., 231: 982-998, 1993.
29. Celis, J E., Dejgaard, K., Madsen, P., Leffers, H , Gesser, B , Honoré, B , Rasmussen, H H., Olsen, E , Lauridsen, J. B., Ratz, G , Mouritzen, S., Basse, B., Hellerup, M., Celis, A., Puype, M , Van Damme, J , and Vandekerckhove, J. The MRC-5 embryonal lung fibroblast two-dimensional gel cellular protein database: quantitative identification of polypeptides whose relative abundance differs between quiescent, proliferating and SV40transformed cells. Electrophoresis, 11: 1072-1113, 1990.
30. Birchmeier, W., and Birchmeier, C. Epithelial-mesenchymal transitions in development and tumor progression. In: I. D. Goldberg and E. M. Rosen (eds.), Epithelial-Mesenchymal Interactions in Cancer, pp. 1-15. Basel: Berkhaeuser Verlag, 1995.
31. Zhong, S , Spurr, N K , Hayes, J. D, and Wolf, C R. Deduced amino acid sequence, gene structure and chromosomal location of a novel human class Mu glutathione S-transferase, GSTM4. Biochem. J , 291: 41-50, 1993.
32. Ensor, C. M., Yang, J. Y., Okita, R. T., and Tai, H. H. Cloning and sequence analysis of the cDNA for human placental NAD(+)-dependent 15-hydroxyprostaglandin dehydrogenase. J Biol. Chem , 265: 14888-14891, 1990.
33. Baxa, C. A., Sha, R. S , Buelt, M. K., Smith, A J , Matarese, V., Chinander, L. L , Boundy, K. L., and Bernlohr, D. A. Human adipocyte lipid-binding protein: purification of the protein and cloning of its complementary DNA. Biochemistry, 28: 8683-8690, 1989.
34. Lamm, D. L. Carcinoma in situ. Urol Clin North Am., 19: 499-508, 1992
35. Rosin, M P , Cairns, P , Epstein, J. I., Schoenberg, M. P., and Sidransky, D. Partial allelotype of carcinoma in situ of the human bladder. Cancer Res., 55: 5213-5216, 1995.
36. Berner, A., Jacobsen, A. B., Fossa, S. D., and Nesland, J. M. Expression of c-erbB-2 protein, neuron-specific enolase and DNA flow cytometry in locally advanced transitional cell carcinoma of the urinary bladder. Histopathology, 22: 327-333, 1993.
37. Lopez, J. I., Angulo, J. C., Flores, N., and Toledo, J D. Small cell carcinoma of the urinary bladder Br. J Urol., 73: 43-49, 1994.
38. Veerkamp, J. H., Paulussen, R. J , Peeters, R. A., Maatman, R. G., van-Moerkerk, H. T., and van-Kuppevelt, T. H. Detection, tissue distribution and (sub)cellular localization of fatty acid-binding protein types. Mol. Cell. Biochem., 98: 11-18, 1990.
39. Glatz, J. F., Vork, M. M., Cistola, D. P., and van-der-Vusse, G J. Cytoplasmic fatty acid binding protein: significance for intracellular transport of fatty acids and putative role in signal transduction pathways. Prostaglandins Leukotrienes Essent. Fatty Acids, 48: 33-41, 1993.
40. Spitsberg, V. L , Matitashvili, E., and Gorewit, R. C. Association and coexpression of fatty-acid-binding protein and glycoprotein CD36 in bovine mammary gland. Eur J. Biochem., 230: 872-878, 1995
41. Glatz, J. F., Borchers, T., Spener, P., and van-der-Vusse, G. J. Fatty acids in cell signalling: modulation by lipid binding proteins. Prostaglandins Leukotrienes Essent. Fatty Acids, 52: 121-127, 1995.
42. Nielsen, S. U., and Spener, F. Fatty acid-binding protein from rat heart is phosphorylated on Tyr19 in response to insulin stimulation. J. Lipid Res., 34: 1355-1366, 1993
43. Nielsen, S. U., Rump, R., Højrup, P., Roepstorff, P., and Spener, F. Differentiational regulation and phosphorylation of the fatty acid-binding protein from rat mammary epithelial cells. Biochim. Biophys Acta, 1211: 189-197, 1994.
44. Spener, F., Unterberg, C., Borchers, T., and Grosse, R. Characteristics of fatty acid-binding proteins and their relation to mammary-derived growth inhibitor. Mol. Cell. Biochem., 98: 57-68, 1990.
45. Yang, Y , Spitzer, E , Kenney, N., Zschiesche, W., Li, M., Kromminga, A., Muller, T., Spener, F., Lezius, A, Veerkamp, J. H., Smith, G H , Salomon, D S , and Grosse, R. Members of the fatty acid binding protein family are differentiation factors for the mammary gland. J. Cell Biol., 127: 1097-1109, 1994
46. Huynh, H T, Larsson, C., Narod, S., and Pollak, M. Tumor suppressor activity of the gene encoding mammary-derived growth inhibitor. Cancer Res., 55. 2225-2231, 1995.
47. Madsen, P., Rasmussen, H H., Leffers, H., Honoré, B., and Celis, J. E. Molecular cloning and expression of a novel keratinocyte protein (psoriasis-associated fatty-acid binding protein [PA-FABP]) that is highly up-regulated in psoriatic skin and that shares similarity to fatty-acid binding proteins J. Invest. Dermatol., 99: 299-305, 1992.
48. Christensen, B., Kieler, J., Vilien, M , Don, P., Wang, C. Y , and Wolf, H. A classification of human urothelial cells propagated in vitro. Anticancer Res , 4: 319-337, 1984.
49. Tew, K. D Glutathione-associated enzymes in anticancer drug resistance. Cancer Res., 54. 4313-4320, 1994.
50. Anggard, E. The biological activities of three metabolites of prostaglandin E1. Acta Physiol. Scand., 66: 509-510, 1966.
51. Erwich, J. J , and Keirse, M. J. Placental localization of 15-hydroxy-prostaglandin dehydrogenase in early and term human pregnancy. Placenta, 13: 223-229, 1992.
52. Shibata, M. A., Yamada, M , Asakawa, E , Hagiwara, A., and Fukushima, S. Responses of rat urine and urothelium to bladder tumor promoters: possible roles of prostaglandin E2 and ascorbic acid synthesis in bladder carcinogenesis. Carcinogenesis (Lond.), 10: 1651-1656, 1989.
53. Schaafsma, H. E., Ramaekers, F. C. van-Muijen, G. N., Lane, E. B , Leigh, I M., Robben, H., Huijsmans, A , Ooms, E. C., and Ruiter, D J. Distribution of cytokeratin polypeptides in human transitional cell carcinomas, with special emphasis on expression patterns during tumor progression. Am. J. Pathol., 136. 329-343, 1990.
54. Hampson, I. N., Pope, L., Cowling, G J., and Dexter, T. M. Chemical cross linking subtraction (CCLS): a new method for the generation of subtractive hybridisation probes. Nucleic Acids Res., 20: 2899, 1992.