Targeting extracellular pyrophosphates underpins the high selectivity of nisin

FASEB Journal

Volumn 18, Issue 15, 2004, Pages 1862-1869

  Bonev, Boyan B ^a,d   Breukink, Eefjan ^b   Swiezewska, E ^c   De Kruijff, Ben ^b   Watts, Anthony ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UTRECHT UNIVERSITY   (Netherlands)

^c INSTITUTE OF BIOCHEMISTRY AND BIOPHYSICS   (Poland)

^d UNIVERSITY OF NOTTINGHAM   (United Kingdom)

Author keywords

Lantibiotic; Penicillin binding protein; Staphylococcal resistance; Vancomycin

Indexed keywords

ALANINE DERIVATIVE; ANTIBIOTIC AGENT; LIPID; NISIN; PENICILLIN G; PYROPHOSPHORIC ACID DERIVATIVE; VANCOMYCIN;

ARTICLE; BACTERIAL CELL WALL; CELL MEMBRANE; CELL WALL; HYDROGEN BOND; PRECURSOR; PRIORITY JOURNAL; PROTEIN TARGETING;

AMINO ACID SEQUENCE; ANTI-BACTERIAL AGENTS; BINDING SITES; CELL WALL; DIPHOSPHATES; LIPID BILAYERS; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR SEQUENCE DATA; NISIN; PEPTIDOGLYCAN; POLYISOPRENYL PHOSPHATES; URIDINE DIPHOSPHATE N-ACETYLMURAMIC ACID;

BACTERIA (MICROORGANISMS);

EID: 10044290579     PISSN: 08926638     EISSN: None     Source Type: Journal    
DOI: 10.1096/fj.04-2358com     Document Type: Article

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