The role of antibiotic prophylaxis in prevention of wound infection after lichtenstein open mesh repair of primary inguinal hernia: A multicenter double-blind randomized controlled trial

Annals of Surgery

Volumn 240, Issue 6, 2004, Pages 955-961

  Aufenacker, Theo J ^a   Van Geldere, Dirk ^b   Van Mesdag, Taco ^a   Bossers, Astrid N ^a   Dekker, Benno ^a   Scheijde, Edo ^a   Van Nieuwenhuizen, Roos ^c   Hiemstra, Esther ^c   Maduro, John H ^c   Juttmann, Jan Willem ^c   Hofstede, Diederik ^a   Van Der Linden, Cunera T M ^a   Gouma, Dirk J ^d   Simons, Maarten P ^a   Sitges Serra, ^a   O'Connors, ^a   Clavien, ^a  

^a Onze Lieve Vrouwe Gasthuis ^*

^b AMSTELLAND HOSPITAL   (Netherlands)

^c Ziekenhuis Hilversum   (Netherlands)

^d UNIVERSITY OF AMSTERDAM   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; CEFUROXIME; CEPHALOSPORIN; PLACEBO;

ADULT; ALLERGY; ANTIBIOTIC PROPHYLAXIS; CLINICAL TRIAL; CONFERENCE PAPER; CONFIDENCE INTERVAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; FEMALE; HUMAN; INGUINAL HERNIA; LICHTENSTEIN OPEN MESH REPAIR; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; PREOPERATIVE PERIOD; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RECURRENT DISEASE; RISK REDUCTION; STATISTICAL ANALYSIS; SURGICAL TECHNIQUE; TIME SERIES ANALYSIS; WOUND INFECTION;

ANTI-BACTERIAL AGENTS; ANTIBIOTIC PROPHYLAXIS; CEFUROXIME; DIGESTIVE SYSTEM SURGICAL PROCEDURES; DOUBLE-BLIND METHOD; FEMALE; HERNIA, INGUINAL; HUMANS; MALE; MIDDLE AGED; SURGICAL MESH; SURGICAL WOUND INFECTION;

EID: 10044282948     PISSN: 00034932     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.sla.0000145926.74300.42     Document Type: Conference Paper

References (31)

1. Bay-Nielsen M, Kehlet M, Strand L, et al. Quality assessment of 26304 herniorrhaphies in Denmark: a prospective nationwide study. Lancet. 2001;358:1124-1128.
2. Hair A, Duffy K, McLean J, et al. Groin hernia repair in Scotland. Br J Surg. 2000;87:1722-1726.
3. Nilsson E, Haapaniemi S, Gruber G, et al. Methods of repair and risk for reoperation in Swedish hernia surgery from 1992 to 1996. Br J Surg. 1998;85:1686-1691.
4. Nyhus LM, Alani A, O'Dwyer PJ, et al. The problem: how to treat a hernia. In: Schumpelick V, Nyhus LM, eds. Meshes: Benefits and Risks, 1st ed. Berlin: Springer-Verlag, 2004:3-30.
5. EU Hernia Trialists Collaboration. Mesh compared with non-mesh methods of open groin hernia repair: systematic review of randomized controlled trials. Br J Surg. 2000;87:854-859.
6. EU Hernia Trialists Collaboration. Repair of groin hernia with synthetic mesh: meta-analysis of randomized controlled trials. Ann Surg. 2002;235:322-332.
7. Lichtenstein IL, Shulman AG, Amid PK, et al. The tension-free hernioplasty. Am J Surg. 1989;157:188-193.
8. Stephenson BM. Complications of open groin hernia repair. Surg Clin North Am. 2003;83:1255-1278.
9. st ed. Wagner Design, 1996:49.
10. Yerdel MA, Akin EB, Dolalan S, et al. Effect of single-dose prophylactic ampicillin and sulbactam on wound infection after tension-free inguinal hernia repair with polypropylene mesh. Ann Surg. 2001;233:26-33.
11. Morales R, Carmona A, Pagán A, et al. Utility of antibiotic prophylaxis in reducing wound infection in inguinal or femoral hernia repair using polypropylene mesh. Cir Esp. 2000;67:51-59.
12. Gilbert Al, Felton LL. Infection in inguinal hernia repair considering biomaterials and antibiotics. Surg Gynecol Obstet. 1993;177:126-130.
13. Sanchez-Manuel FJ, Seco-Gil JL. Antibiotic prophylaxis for hernia repair (Cochrane Review). In: The Cochrane Library, Issue 2. Oxford: Update software, 2003.
14. Vrijland WW, van den Tol MP, Luijendijk RW, et al. Randomized clinical trial of non-mesh versus mesh repair of primary inguinal hernia. Br J Surg. 2002;89:293-297.
15. Nordin P, Bartelmess P, Jansson C, et al. Randomized trial of Lichtenstein versus Shouldice hernia repair in general surgical practice. Br J Surg. 2002;89:45-49.
16. Rutkow IM. Demographic and socioeconomic aspects of hernia repair in the United States in 2003. Surg Clin North Am. 2003;83:1045-1051.
17. Waldvogel FA, Vaudaux PE, Pittet D, et al. Perioperative antibiotic prophylaxis of wound and foreign body infections: microbial factors affecting efficacy. Rev Infect Dis. 1991;13(suppl):782-789.
18. Horan TC, Gaynes RP, Martone WJ, et al. CDC definitions of nosocomial surgical site infections, 1992: a modification of CDC definitions of surgical wound infections. Am J Infect Control. 1992;20:271-274.
19. Mangram AJ, Horan TC, Pearson ML, et al. Guideline for prevention or surgical site infection, 1999. Infect Control Hosp Epidemiol. 1999;20:247-280.
20. Boxma H, Broekhuizen T, Patka P, et al. Randomised controlled trial of single-dose antibiotic prophylaxis in surgical treatment of closed fractures: the Dutch Trauma Trial. Lancet. 1996;347:1133-1137.
21. Pitt HA, Postier RG, MacGowan AW, et al. Prophylactic antibiotics in vascular surgery: topical, systemic or both? Ann Surg. 1980;192:359-364.
22. DaCosta A, Kirkorian G, Cuccherat M, et al. Antibiotic prophylaxis for permanent pacemaker implantation, a meta-analysis. Circulation. 1998;97:1796-1801.
23. Simchen E, Rozin R, Wax Y. The Israeli study of surgical infection of drains and the risk of wound infection in operation for hernia. Surg Gynecol Obstet. 1990;170:331-337.
24. Classen DC, Evans RS, Pestotnik SL, et al. The timing of prophylactic administration of antibiotics and the risk of surgical wound infection. N Engl J Med. 1992;326:281-286.
25. Whitby M, McLaws M-L, Collopy B, et al. Post-discharge surveillance: can patients reliably diagnose wound infections? J Hosp Infect. 2002;55:154-160.
26. Reilly JS, Baird D, Hill R. The importance of definitions and methods in surgical wound infection audit. J Hosp Infect. 2001;47:64-66.
27. Source: Z-index database of Koninklijke Nederlandse Maatschappij ter bevordering der Pharmacie (KNMP), The Hague, The Netherlands. http://www.knmp.nl [in Dutch]. Accessed December 2003.
28. Glassovv F. Is postoperative wound infection following simple inguinal herniorrhaphy a predisposing cause for recurrent hernia? Can J Surg. 1964;91:870-871.
29. Meyers RN, Shearburn EW. The problem of recurrent inguinal hernia. Surg Clin North Am. 1973;53:555-558.
30. Mann DV, Prout J, Havranek E, et al. Late-onset deep prosthetic infection following mesh repair of inguinal hernia. Am J Surg. 1998;176:12-14.
31. Taylor SG, O'Dwyer PJ. Chronic groin sepsis following tension-free inguinal hernioplasty. Br J Surg. 1999;86:562-565.