Acetaminophen in the hypoxic and reoxygenated guinea pig myocardium

Experimental Biology and Medicine

Volumn 229, Issue 11, 2004, Pages 1154-1161

  Rork, Tyler H ^a   Van Dyke, Knox ^b   Spiler, Norell M ^a   Merrill, Gary F ^a  

^a RUTGERS UNIVERSITY   (United States)

^b WEST VIRGINIA UNIVERSITY   (United States)

Author keywords

Cardioprotection; Chemiluminescence; Langendorff; Peroxynitrite; Ventricular function

Indexed keywords

PARACETAMOL; REACTIVE OXYGEN METABOLITE;

ANIMAL MODEL; CHEMOLUMINESCENCE; CONFERENCE PAPER; CONTROLLED STUDY; CORONARY HEMODYNAMICS; ELECTRON MICROSCOPY; GUINEA PIG; HEART LEFT VENTRICLE; HEART MUSCLE; HEMODYNAMICS; HYPOXIA; MALE; MEDICAL RECORD; NONHUMAN; REDUCTION; REOXYGENATION;

ANIMALIA; CAVIA PORCELLUS; SUS SCROFA;

EID: 10044279169     PISSN: 15353702     EISSN: None     Source Type: Journal    
DOI: 10.1177/153537020422901110     Document Type: Conference Paper

References (33)

1. Prescott LF. Paracetamol (acetaminophen): a critical bibliographic review. London: Taylor and Francis, 2001.
2. Golfetti R, Rork T, Merrill G. Chronically administered acetaminophen and the ischemia/reperfused myocardium. Exp Biol Med 228:674-682, 2003.
3. Golfetti R, VanDyke K, Rork T, Spiler N, Merrill G. Acetaminophen in the post-ischemia reperfused myocardium. Exp Biol Med 227:1031-1037, 2002.
4. Merrill GF. Acetaminophen and low-flow myocardial ischemia: efficacy and antioxidant mechanisms. Am J Physiol Heart 282:H1341-H1349, 2002.
5. Merrill GF, Goldberg E. Antioxidant properties of acetaminophen and cardioprotection. Basic Res Cardiol 96:423-430, 2001.
6. Merrill G, McConnell P, VanDyke K, Powell S. Coronary and myocardial effects of acetaminophen: protection during ischemia-reperfusion. Am J Physiol Heart 280:H2631-H2638, 2001.
7. Karmazyn M, Pierce GN, Williams S. Effect of nonsteroidal anti-inflammatory drugs on the hypoxic rat heart. J Pharmacol Exp Ther 218:488-496, 1981.
8. Teng RJ, Ye YZ, Parks DA, Beckman JS. Urate produced during hypoxia protects heart proteins from peroxynitrite-mediated protein nitration. Free Radic Biol Med 33:1243-1249, 2002.
9. Samaja M, Motterlini R, Santoro F, Dell'Antonio G, Corno A. Oxidative injury in reoxygenated and reperfused hearts. Free Radic Biol Med 16:255-262, 1994.
10. Hunger R, Haddy FJ, Gerlach E. Coronary responses to dilating substances and competitive inhibition by theophylline in the isolated perfused guinea pig heart. Pflugers Arch 353:212-224, 1975.
11. Bunger R, Haddy FJ, Querengasser A, Gerlach E. An isolated guinea pig heart preparation with in vivo like features. Pflugers Arch 353:317-326, 1975.
12. Kang YH, Wei HM, Merrill GF. Role of adenosine in catecholamine-induced global coronary functional hyperemia in isolated guinea pig hearts. J Cardiovasc Pharmacol 15:939-945, 1990.
13. Merrill GF, Haddy FJ, Dabney JM. Adenosine, theophylline, and perfusate pH in the isolated, perfused guinea pig heart. Circ Res 42:225-229, 1978.
14. Wei HM, Friedrichs GS, Merrill GF. Route dependent effects of 2-chloroadenosine and theophylline in isolated perfused guinea pig hearts. Cardiovasc Res 25:529-536, 1991.
15. Stowe DF. Vasodilator responses to moderate hypoxia after submaximal adenosine injection or coronary occlusion in isolated perfused guinea pig hearts. Circ Res 47:392-399, 1980.
16. Wei HM, Kang YH, Merrill GF. Coronary vasodilation during global myocardial hypoxia: effects of adenosine deaminase. Am J Physiol Heart 254:H1004-H1009, 1988.
17. Szasz G. Laboratory measurement of creatine kinase activity. Proceedings of the Second International Symposium on Clinical Enzymology, October 1975. Chicago: Karger, 1975.
18. Rosalki SB. An improved procedure for serum creatine phosphokinase determination. J Lab Clin Med 69:696-704, 1967.
19. Bazzola JJ, Russel LD. Electron microscopy: principles and techniques for biologists. Jones and Bartlett: Boston, 1991.
20. Van Dyke K, Sacks M, Qazi N. A new screening method to detect water-soluble antioxidants: acetaminophen (Tylenol®) and other phenols react as antioxidants and destroy peroxynitrite-based luminol-dependent chemiluminescence. J Biolumin Chemilumin 13:339-348, 1998.
21. Li Y, Zhu H, Kuppusamy P, Roubaud V, Zweier JL, Trush MA. Validation of lucigenin (Bis-N-methylacridinium) as a chemilumigenic probe for detecting superoxide anion radical production by enzymatic and cellular systems. J Biol Chem 273:2015-2023, 1998.
22. Schmidt HHHW. Determination of nitric oxide via measurement of nitrite and nitrate in culture media. Biochemica 2:22-23, 1995.
23. Asayama J, Yamahara Y, Tatsumi T, Matsumoto T, Miyazaki H, Sakai R, Inoue M, Omori I, Inoue D, Nakagawa M. Effects of reduction of contractile work on mechanical function in post-hypoxic guinea pig papillary muscles and on myocardial energy metabolism in post-ischemic rat hearts. Jpn Circ J 56:292-300, 1992.
24. Vanden Hoek TL, Shao Z, Li C, Zak R, Schumacker PT, Becker LB. Reperfusion injury on cardiac myocytes after stimulated ischemia. Am J Physiol Heart 270:H1334-H1341, 1996.
25. Damerau W, Ibel J, Thurich T, Assadnazari H, Zimmer G. Generation of free radicals in Langendorff and working hearts during normoxia, hypoxia, and reoxygenation. Basic Res Cardiol 88:141-149, 1993.
26. Gaudel Y, Duvelleroy MA. Role of oxygen radicals in cardiac injury due to reoxygenation. J Mol Cell Cardiol 16:459-470, 1984.
27. Liu P, Hock CE, Nagele R, Wong PYK. Formation of nitric oxide, superoxide, and peroxynitrite in myocardial ischemia-reperfusion injury in rats. Am J Physiol Heart 272:H2327-H2336, 1997.
28. Feinberg H, Gerola A, Katz LN, Boyd E. Effect of hypoxia on cardiac oxygen consumption and coronary flow. Am J Physiol Heart 195:593-600, 1958.
29. Mair J. Tissue release of cardiac markers: from physiology to clinical applications. Clin Chem Lab Med 37:1077-1084, 1999.
30. Ferdinandy P, Schulz R. Nitric oxide, superoxide, and peroxynitrite in myocardial ischaemia-reperfusion injury and preconditioning. Br J Pharmacol 138:532-543, 2003.
31. Meister A. Glutathione-ascorbic acid antioxidant system in animals. J Biol Chem 269:9397-9400, 1994.
32. Ma XL, Gao F, Lopez BL, Christopher TA, Vinten-Johansen J. Peroxynitrite, a two-edged sword in post-ischemic myocardial injury. Dichotomy of action in crystalloid versus blood-perfused hearts. J Pharmacol Exp Ther 292:912-920, 2000.
33. Vinten-Johansen J. Physiological effects of peroxynitrite: potential products of the environment. Circ Res 87:170-172, 2000.