Confounding effects of anesthesia on functional activation in rodent brain: A study of halothane and α-chloralose anesthesia

NeuroImage

Volumn 24, Issue 1, 2005, Pages 92-100

  Austin, V C ^a,b   Blamire, A M ^a   Allers, K A ^c   Sharp, T ^c   Styles, P ^a   Matthews, P M ^b   Sibson, N R ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b JOHN RADCLIFFE HOSPITAL   (United Kingdom)

^c UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Chloralose; Anesthetic; BOLD response; fMRI; Halothane; Rat

Indexed keywords

CHLORALOSE; HALOTHANE;

ANESTHESIA INDUCTION; ANIMAL EXPERIMENT; ARTICLE; BLOOD OXYGEN TENSION; CONTROLLED STUDY; DOSE RESPONSE; ELECTROCORTICOGRAPHY; ELECTROSTIMULATION; MALE; MOTOR CORTEX; NERVE CELL EXCITABILITY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; RAT; SIGNAL DETECTION; SPECIES COMPARISON;

ANESTHESIA, GENERAL; ANESTHETICS, INHALATION; ANESTHETICS, INTRAVENOUS; ANIMALS; CHLORALOSE; DOMINANCE, CEREBRAL; ELECTRIC STIMULATION; ELECTROENCEPHALOGRAPHY; EVOKED POTENTIALS, MOTOR; HALOTHANE; HINDLIMB; IMAGE PROCESSING, COMPUTER-ASSISTED; ISOMETRIC CONTRACTION; MAGNETIC RESONANCE IMAGING; MALE; MOTOR CORTEX; OXYGEN; RATS; RATS, SPRAGUE-DAWLEY; SENSITIVITY AND SPECIFICITY;

EID: 10044278238     PISSN: 10538119     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroimage.2004.08.011     Document Type: Article

References (28)

1. M. Alkire, R. Haier, and J. Fallon Toward a unified theory of narcosis: brain imaging evidence for a thalamocortical switch as the neurophysiologic basis of anesthetic-induced unconsciousness Conscious. Cogn. 9 2000 370 386
2. A. Angel The G. L. Brown lecture. Adventures in anaesthesia Exp. Physiol. 76 1991 1 38
3. L.M. Antunes, H.D. Golledge, J.V. Roughan, and P.A. Flecknell Comparison of electroencephalogram activity and auditory evoked responses during isoflurane and halothane anaesthesia in the rat Vet. Anaesth. Analg. 30 2003 15 23
4. V.C. Austin, A.M. Blamire, S.M. Grieve, M.J. O'Neill, P. Styles, P.M. Matthews, and N.R. Sibson Differences in the BOLD fMRI response to direct and indirect cortical stimulation in the rat Magn. Reson. Med. 49 2003 838 847
5. G. Bonvento, R. Charbonne, J.L. Correze, J. Borredon, J. Seylaz, and P. Lacombe Is alpha-chloralose plus halothane induction a suitable anesthetic regimen for cerebrovascular research? Brain Res. 665 1994 213 221
6. S. Clare, M. Humberstone, J. Hykin, L.D. Blumhardt, R. Bowtell, and P. Morris Detecting activations in event-related fMRI using analysis of variance Magn. Reson. Med. 42 1999 1117 1122
7. D.J. Dubowitz, D.Y. Chen, D.J. Atkinson, K.L. Grieve, B. Gillikin, W.G. Bradley Jr., and R.A. Andersen Functional magnetic resonance imaging in macaque cortex NeuroReport 9 1998 2213 2218
8. R.E. Dudley, S.R. Nelson, and F. Samson Influence of chloralose on brain regional glucose utilization Brain Res. 233 1982 173 180
9. S.A. Glantz Primer of Biostatistics 1992 McGraw-Hill Book Co. Singapore
10. F. Hyder, K.L. Behar, M.A. Martin, A.M. Blamire, and R.G. Shulman Dynamic magnetic resonance imaging of the rat brain during forepaw stimulation J. Cereb. Blood Flow. Metab. 14 1994 649 655
11. F. Hyder, D.L. Rothman, and R.G. Shulman Total neuroenergetics support localized brain activity: implications for the interpretation of fMRI Proc. Natl. Acad. Sci. U. S. A. 99 2002 10771 10776
12. F. Hyder, I. Kida, K.L. Behar, R.P. Kennan, P.K. Maciejewski, and D.L. Rothman Quantitative functional imaging of the brain: towards mapping neuronal activity by BOLD fMRI NMR Biomed. 14 2001 413 431
13. K.K. Kaisti, J.W. Langsjo, S. Aalto, V. Oikonen, H. Sipila, M. Teras, S. Hinkka, L. Metsahonkala, and H. Scheinin Effects of sevoflurane, propofol, and adjunct nitrous oxide on regional cerebral blood flow, oxygen consumption, and blood volume in humans Anesthesiology 99 2003 603 613
14. P. Lees Pharmacology and toxicology of alpha chloralose: a review Vet. Rec. 91 1972 330 333
15. M. Levesque, S. Gagnon, A. Parent, and Deschenes Axonal arborizations of corticostriatal and corticothalamic fibers arising from the second somatosensory area in the rat Cereb. Cortex 6 1996 759 770
16. N.K. Logothetis, H. Guggenberger, S. Peled, and J. Pauls Functional imaging of the monkey brain Nat. Neurosci. 2 1999 555 562
17. N.K. Logothetis, J. Pauls, M. Augath, T. Trinath, and A. Oeltermann Neurophysiological investigation of the basis of the fMRI signal Nature 412 2001 150 157
18. Y. Nakao, Y. Itoh, T.Y. Kuang, M. Cook, J. Jehle, and L. Sokoloff Effects of anesthesia on functional activation of cerebral blood flow and metabolism Proc. Natl. Acad. Sci. U. S. A. 98 2001 7593 7598
19. S. Ogawa, T.M. Lee, A.S. Nayak, and P. Glynn Oxygenation-sensitive contrast in magnetic resonance image of rodent brain at high magnetic fields Magn. Reson. Med. 14 1990 68 78
20. R.R. Peeters, I. Tindemans, E. De Schutter, and A. Van der Linden Comparing BOLD fMRI signal changes in the awake and anesthetized rat during electrical forepaw stimulation Magn. Reson. Imaging 19 2001 821 826
21. H. Reddy, D. Bendahan, M.A. Lee, H. Johansen-Berg, M. Donaghy, D. Hilton-Jones, and P.M. Matthews An expanded cortical representation for hand movement after peripheral motor denervation J. Neurol., Neurosurg. Psychiatry 72 2002 203 210
22. E.M. Rouiller, G.M. Simm, A.E. Villa, Y. de Ribaupierre, and F. de Ribaupierre Auditory corticocortical interconnections in the cat: evidence for parallel and hierarchical arrangement of the auditory cortical areas Exp. Brain Res. 86 1991 483 505
23. R.G. Shulman, D.L. Rothman, and F. Hyder Stimulated changes in localized cerebral energy consumption under anesthesia Proc. Natl. Acad. Sci. U. S. A. 96 1999 3245 3250
24. N.R. Sibson, A. Dhankhar, G.F. Mason, D.L. Rothman, K.L. Behar, and R.G. Shulman Stoichiometric coupling of brain glucose metabolism and glutamatergic neuronal activity Proc. Natl. Acad. Sci. U. S. A. 95 1998 316 321
25. A.J. Smith, H. Blumenfeld, K.L. Behar, D.L. Rothman, R.G. Shulman, and F. Hyder Cerebral energetics and spiking frequency: the neurophysiological basis of fMRI Proc. Natl. Acad. Sci. U. S. A. 99 2002 10765 10770
26. L. Stefanacci, P. Reber, J. Costanza, E. Wong, R. Buxton, S. Zola, L. Squire, and T. Albright fMRI of monkey visual cortex Neuron 20 1998 1051 1057
27. M. Ueki, F. Linn, and K.A. Hossmann Functional activation of cerebral blood flow and metabolism before and after global ischemia of rat brain J. Cereb. Blood. Flow Metab. 8 1988 486 494
28. M. Ueki, G. Mies, and K.A. Hossmann Effect of alpha-chloralose, halothane, pentobarbital and nitrous oxide anesthesia on metabolic coupling in somatosensory cortex of rat Acta Anaesthesiol. Scand. 36 1992 318 322