Mequinol 2%/tretinoin 0.01% solution: An effective and safe alternative to hydroquinone 3% in the treatment of solar lentigines

Cutis

Volumn 74, Issue 5, 2004, Pages 319-322

  Jarratt, Michael ^a  

^a DermResearch Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HYDROQUINONE; MEQUINOL PLUS RETINOIC ACID;

ADULT; AGED; ARTICLE; BURNING SENSATION; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG SAFETY; ERYTHEMA; FEMALE; FOLLOW UP; FOREARM; HUMAN; HYPERPIGMENTATION; LENTIGO; MALE; MULTICENTER STUDY; PHYSICIAN; PRURITUS; RANDOMIZED CONTROLLED TRIAL; RASH; SIDE EFFECT; SKIN DEFECT; SKIN PIGMENTATION; SKIN TINGLING; TREATMENT OUTCOME;

ADMINISTRATION, CUTANEOUS; ADULT; AGED; AGED, 80 AND OVER; ANISOLES; DOUBLE-BLIND METHOD; DRUG THERAPY, COMBINATION; FACE; FEMALE; FOREARM; HUMANS; HYDROQUINONES; KERATOLYTIC AGENTS; LENTIGO; MALE; MIDDLE AGED; TREATMENT OUTCOME; TRETINOIN;

EID: 10044267428     PISSN: 00114162     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (10)

1. Todd MM, Rallis TM, Gerwels JW, et al. A comparison of 3 lasers and liquid nitrogen in the treatment of solar lentigines: a randomized, controlled, comparative trial. Arch Dermatol. 2000;136:841-846.
2. Hexsel DM, Mazzuco R, Bohn J, et al. Clinical comparative study between cryotherapy and local dermabrasion for the treatment of solar lentigo on the back of the hands. Dermatol Surg. 2000;26:457-462.
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5. Arndt KA, Fitzpatrick TB. Topical use of hydroquinone as a depigmenting agent. JAMA. 1965;194:965-967.
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8. Nair X, Parab P, Suhr L, et al. Combination of 4-hydroyanisole and all-trans retinoic acid produces synergistic skin depigmentation in swine. J Invest Dermatol. 1993;101:145-149.
9. Fleischer AB Jr, Schwartzel EH, Colby SI, et al. The combination of 2% 4-hydroxyanisole (mequinol) and 0.01% tretinoin is effective in improving the appearance of solar lentigines and related hyperpigmented lesions in two double-blind multicenter clinical studies. J Am Acad Dermatol. 2000;42:459-467.
10. Kopera D, Hohenleutner U, Landthaler M. Q-switched ruby laser application is safe and effective for the management of actinic lentigo (topical glycolic acid is not). Acta Derm Venereol. 1996;76:461-463.