Does haploidentical transplantation in children with primary immunodeficiencies have the potential to exploit donor NK cell alloreactivity?

Bone Marrow Transplantation

Volumn 34, Issue 11, 2004, Pages 945-947

  Dal Cortivo, L ^a   Ouachee Chardin M ^a   Hirsch, I ^a   Blanche, S ^a   Fischer, A ^a   Cavazzana Calvo, M ^a   Caillat Zucman, S ^a  

^a HÔPITAL NECKER ENFANTS MALADES   (France)

Author keywords

Alloreactivity; GVHD; KIR; NK cell

Indexed keywords

BUSULFAN; CD34 ANTIGEN; CYCLOPHOSPHAMIDE; IMMUNOGLOBULIN RECEPTOR; LIGAND; LYMPHOCYTE ANTIBODY; MONOCLONAL ANTIBODY; THYMOCYTE ANTIBODY;

ALLOIMMUNITY; ARTICLE; CANCER MORTALITY; CANCER PATIENT; CANCER SURVIVAL; CELL SELECTION; CHILD; CLINICAL ARTICLE; COMPLEMENT DEPENDENT CYTOTOXICITY; CONTROLLED STUDY; DONOR; GRAFT VERSUS HOST REACTION; HAPLOIDY; HEMATOLOGIC MALIGNANCY; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMAN; IMMUNE DEFICIENCY; IMMUNOSUPPRESSIVE TREATMENT; LYMPHOCYTE DEPLETION; NATURAL KILLER CELL; PRIORITY JOURNAL; T LYMPHOCYTE;

CHILD, PRESCHOOL; FEMALE; GRAFT VS HOST DISEASE; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMANS; KILLER CELLS, NATURAL; LYMPHOCYTE DEPLETION; MALE; RECEPTORS, IMMUNOLOGIC; SEVERE COMBINED IMMUNODEFICIENCY; TRANSPLANTATION CONDITIONING; TRANSPLANTATION, HOMOLOGOUS;

EID: 10044263082     PISSN: 02683369     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bmt.1704663     Document Type: Article

References (7)

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6. Lowe EJ, Turner V, Handgretinger R et al.. T-cell alloreactivity dominates natural killer cell alloreactivity in minimally T-cell-depleted HLA-non-identical paediatric bone marrow transplantation. Br J Haematol 2003; 123: 323-326.
7. Velardi A. Impact of NK cell alloreactivity on mismatched hematopoietic transplantation: an update on donor selection criteria and on transplantation outcomes. In: Blood. ASH: San Diego, 2003.