An improved process for the large-scale preparation of antirheumatic agent MX-68

Organic Process Research and Development

Volumn 8, Issue 6, 2004, Pages 883-888

  Maruyama, Noriaki ^a   Shimizu, Hirohito ^a   Sugiyama, Takashi ^a   Watanabe, Masashi ^a   Makino, Masashi ^a   Kato, Masahiro ^a   Shimizu, Makoto ^b  

^a CHUGAI PHARMACEUTICAL CO LTD   (Japan)

^b MIE UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ALKANE DERIVATIVE; ANTIRHEUMATIC AGENT; N [[4 [(2,4 DIAMINO 6 PTERIDINYL)METHYL] 3,4 DIHYDRO 2H 1,4 BENZOTHIAZIN 7 YL]CARBONYL]HOMOGLUTAMIC ACID;

ARTICLE; CHROMATOGRAPHY; DRUG SYNTHESIS; LABORATORY; PURIFICATION; TOXICITY TESTING;

EID: 10044255444     PISSN: 10836160     EISSN: None     Source Type: Journal    
DOI: 10.1021/op049867y     Document Type: Article

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