Activation of cytotoxic lymphocytes by interferon-α: Role of oxygen radical-producing mononuclear phagocytes

Journal of Leukocyte Biology

Volumn 76, Issue 6, 2004, Pages 1207-1213

  Hansson, Markus ^a   Romero, Ana ^b   Thorén, Fredrik ^b   Hermodsson, Svante ^b   Hellstrand, Kristoffer ^b  

^a LUND UNIVERSITY   (Sweden)

^b UNIVERSITY OF GOTHENBURG   (Sweden)

Author keywords

CD69; Histamine; NK cell; NK T cell; ROS; T cell

Indexed keywords

CATALASE; CD3 ANTIGEN; CD3EPSILON ANTIGEN; CD56 ANTIGEN; CD69 ANTIGEN; CD8 ANTIGEN; DIPHENYLIODONIUM SALT; GAMMA INTERFERON; HISTAMINE; OXYGEN RADICAL; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SCAVENGER; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL DEATH; CELL SURFACE; CELL VIABILITY; CHRONIC DISEASE; CLONAL ANERGY; CONTROLLED STUDY; CYTOTOXIC LYMPHOCYTE; HUMAN; HUMAN CELL; IMMUNOREACTIVITY; IMMUNOSTIMULATION; INFECTION; LYMPHOCYTE ACTIVATION; LYMPHOCYTE FUNCTION; MONONUCLEAR CELL; NATURAL KILLER CELL; PHAGOCYTE; PHENOTYPE; PRIORITY JOURNAL; T LYMPHOCYTE; VIRUS INFECTION;

ANTIGENS, CD; ANTIGENS, CD3; ANTIGENS, DIFFERENTIATION, T-LYMPHOCYTE; APOPTOSIS; CELL COMMUNICATION; CELLS, CULTURED; CYTOTOXICITY, IMMUNOLOGIC; ENZYME INHIBITORS; FREE RADICAL SCAVENGERS; HUMANS; IMMUNE TOLERANCE; INTERFERON-ALPHA; KILLER CELLS, NATURAL; LEUKOCYTES, MONONUCLEAR; LYMPHOCYTE ACTIVATION; LYMPHOCYTES; NADPH OXIDASE; OXIDATIVE STRESS; PHAGOCYTES; REACTIVE OXYGEN SPECIES; T-LYMPHOCYTES, CYTOTOXIC;

LETHRINIDAE;

EID: 10044254646     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: 10.1189/jlb.0204113     Document Type: Article

References (43)

1. Wai, C. T., Lok, A. S. (2002) Treatment of hepatitis B. J. Gastroenterol. 37, 771-778.
2. Chander, G., Sulkowski, M. S., Jenckes, M. W., Torbenson, M. S., Herlong, H. F., Bass, E. B., Gebo, K. A. (2002) Treatment of chronic hepatitis C: a systematic review. Hepatology 36, S135-S144.
3. Kirkwood, J. (2002) Cancer immunotherapy: the interferon-α experience. Semin. Oncol. 29, 18-26.
4. Herberman, R. B. (1997) Effect of α-interferons on immune function. Semin. Oncol. 24, S9-78-S9-80.
5. Burchert, A., Wolfl, S., Schmidt, M., Brendel, C., Denecke, B., Cai, D., Odyvanova, L., Lahaye, T., Muller, M. C., Berg, T., Gschaidmeier, H., Wittig, B., Hehlmann, R., Hochhaus, A., Neubauer, A. (2003) Interferon-α, but not the ABL-kinase inhibitor imatinib (STI571), induces expression of myeloblastin and a specific T-cell response in chronic myeloid leukemia. Blood 101, 259-264.
6. Morishima, C., Musey, L., Elizaga, M., Gaba, K., Allison, M., Carithers, R. L., Gretch, D. R., McElrath, M. J. (2003) Hepatitis C virus-specific cytolytic T cell responses after antiviral therapy. Clin. Immunol. 108, 211-220.
7. Edwards, B. S., Hawkins, M. J., Borden, E. C. (1984) Comparative in vivo and in vitro activation of human natural killer cells by two recombinant α-interferons differing in antiviral activity. Cancer Res. 44, 3135-3139.
8. Dumont, F. J. (1986) Treatment of resting T lymphocytes with interferon-α/β augments their proliferative response to activation signals delivered through their surface Ly-6 antigen. Cell. Immunol. 101, 625-632.
9. Jinushi, M., Takehara, T., Kanto, T., Tatsumi, T., Groh, V., Spies, T., Miyagi, T., Suzuki, T., Sasaki, Y., Hayashi, N. (2003) Critical role of MHC class I-related chain A and B expression on IFN-α-stimulated dendritic cells in NK cell activation: impairment in chronic hepatitis C virus infection. J. Immunol. 170, 1249-1256.
10. Vose, B. M., Moore, M. (1985) Human tumor-infiltrating lymphocytes: a marker of host response. Semin. Hematol. 22, 27-40.
11. Rugge, M., Vanstapel, M. J., Ninfo, V., Realdi, G., Tremolada, F., Montanari, P. G., van Damme, B., Fevery, J., de Groote, J., Desmet, V. (1983) Comparative histology of acute hepatitis B and non-A, non-B in Leuven and Padova. Virchows Arch. A Pathol. Anat. Histopathol. 401, 275-288.
12. Hellstrand, K., Asea, A., Dahlgren, C., Hermodsson, S. (1994) Histaminergic regulation of NK cells. Role of monocyte-derived reactive oxygen metabolites. J. Immunol. 153, 4940-4947.
13. Hansson, M., Asea, A., Ersson, U., Hermodsson, S., Hellstrand, K. (1996) Induction of apoptosis in NK cells by monocyte-derived reactive oxygen metabolites. J. Immunol. 156, 42-47.
14. Kono, K., Salazar-Onfray, F., Petersson, M., Hansson, J., Masucci, G., Wasserman, K., Nakazawa, T., Anderson, P., Kiessling, R. (1996) Hydrogen peroxide secreted by tumor-derived macrophages down-modulates signal-transducing ζ molecules and inhibits tumor-specific T cell- and natural killer cell-mediated cytotoxicity. Eur. J. Immunol. 26, 1308-1313.
15. Betten, A., Dahlgren, C., Hermodsson, S., Hellstrand, K. (2001) Serotonin protects NK cells against oxidatively induced functional inhibition and apoptosis. J. Leukoc. Biol. 70, 65-72.
16. Hansson, M., Hermodsson, S., Brune, M., Mellqvist, U. H., Naredi, P., Betten, A., Gehlsen, K. R., Hellstrand, K. (1999) Histamine protects T cells and natural killer cells against oxidative stress. J. Interferon Cytokine Res. 19, 1135-1144.
17. Hellstrand, K. (2003) Melanoma immunotherapy: a battle against radicals? Trends Immunol. 24, 232-233.
18. Whiteside, T. L. (1999) Signaling defects in T lymphocytes of patients with malignancy. Cancer Immunol. Immunother. 48, 346-352.
19. Kiessling, R., Wasserman, K., Horiguchi, S., Kono, K., Sjoberg, J., Pisa, P., Petersson, M. (1999) Tumor-induced immune dysfunction. Cancer Immunol. Immunother. 48, 353-362.
20. Lanier, L. L., Buck, D. W., Rhodes, L., Ding, A., Evans, E., Barney, C., Phillips, J. H. (1988) Interleukin 2 activation of natural killer cells rapidly induces the expression and phosphorylation of the Leu-23 activation antigen. J. Exp. Med. 167, 1572-1585.
21. Gerosa, F., Scardoni, M., Tommasi, M., Benati, C., Snelli, L., Gandini, G., Libonati, M., Tridente, G., Carra, G. (1991) Interferon α induces expression of the CD69 activation antigen in human resting NK cells, while interferon γ and tumor necrosis factor α are ineffective. Int. J. Cancer 48, 473-475.
22. Rabinowich, H., Herberman, R. B., Whiteside, T. L. (1993) Differential effects of IL12 and IL2 on expression and function of cellular adhesion molecules on purified human natural killer cells. Cell. Immunol. 152, 481-498.
23. Wilson, M. T., Singh, A. K., Van Kaer, L. (2002) Immunotherapy with ligands of natural killer T cells. Trends Mol. Med. 8, 225-231.
24. Asea, A., Hansson, M., Czerkinsky, C., Houze, T., Hermodsson, S., Strannegard, O., Hellstrand, K. (1996) Histaminergic regulation of interferon-γ (IFN-γ) production by human natural killer (NK) cells. Clin. Exp. Immunol. 105, 376-382.
25. Mellqvist, U. H., Hansson, M., Brune, M., Dahlgren, C., Hermodsson, S., Hellstrand, K. (2000) Natural killer cell dysfunction and apoptosis induced by chronic myelogenous leukemia cells: role of reactive oxygen species and regulation by histamine. Blood 96, 1961-1968.
26. Allen, R. T., Hunter III, W. J., Agrawal, D. K. (1997) Morphological and biochemical characterization and analysis of apoptosis. J. Pharmacol. Toxicol. Methods 37, 215-228.
27. Sun, S., Zhang, X., Tough, D., Sprent, J. (2000) Multiple effects of immunostimulatory DNA on T cells and the role of type I interferons. Springer Semin. Immunopathol. 22, 77-84.
28. Hansson, M., Asea, A., Hermodsson, S., Hellstrand, K. (1996) Histaminergic regulation of NK-cells: protection against monocyte-induced apoptosis. Scand. J. Immunol. 44, 193-196.
29. Hellstrand, K., Asea, A., Hermodsson, S. (1990) Role of histamine in natural killer cell-mediated resistance against tumor cells. Monocyte-mediated suppression of IL-2-induced NK-cell activation. Regulation by 5-HT1A-type serotonin receptors. J. Immunol. 145, 4365-4370.
30. Miesel, R., Kurpisz, M., Kroger, H. (1996) Suppression of inflammatory arthritis by simultaneous inhibition of nitric oxide synthase and NADPH oxidase. Free Radic. Biol. Med. 20, 75-81.
31. Hellstrand, K., Asea, A., Hermodsson, S. (1994) Histaminergic regulation of antibody-dependent cellular cytotoxicity of granulocytes, monocytes, and natural killer cells. J. Leukoc. Biol. 55, 392-397.
32. Alleva, D. G., Walker, T. M., Elgert, K. D. (1995) Induction of macrophage suppressor activity by fibrosarcoma-derived transforming growth factor-β I: contrasting effects on resting and activated macrophages. J. Leukoc. Biol. 57, 919-928.
33. Kono, H., Rusyn, I., Yin, M., Gabele, E., Yamashina, S., Dikalova, A., Kadiiska, M. B., Connor, H. D., Mason, R. P., Segal, B. H., Bradford, B. U., Holland, S. M., Thurman, R. G. (2000) NADPH oxidase-derived free radicals are key oxidants in alcohol-induced liver disease. J. Clin. Invest. 106, 867-872.
34. Samlowski, W. E., Petersen, R., Cuzzocrea, S., Macarthur, H., Burton, D., McGregor, J. R., Salvemini, D. (2003) A nonpeptidyl mimic of superoxide dismutase, M40403, inhibits dose-limiting hypotension associated with interleukin-2 and increases its antitumor effects. Nat. Med. 9, 750-755.
35. Saba, T. M. (1970) Physiology and physiopathology of the reticuloendothelial system. Arch. Intern. Med. 126, 1031-1052.
36. Valgimigli, M., Valgimigli, L., Trere, D., Gaiani, S., Pedulli, G. F., Gramantieri, L., Bolondi, L. (2002) Oxidative stress EPR measurement in human liver by radical-probe technique. Correlation with etiology, histology and cell proliferation. Free Radic. Res. 36, 939-948.
37. Bureau, C., Bernad, J., Chaouche, N., Orfila, C., Beraud, M., Gonindard, C., Alric, L., Vinel, J. P., Pipy, B. (2001) Nonstructural 3 protein of hepatitis C virus triggers an oxidative burst in human monocytes via activation of NADPH oxidase. J. Biol. Chem. 276, 23077-23083.
38. Kakimi, K., Guidotti, L. G., Koezuka, Y., Chisari, F. V. (2000) Natural killer T cell activation inhibits hepatitis B virus replication in vivo. J. Exp. Med. 192, 921-930.
39. Biron, C. A., Nguyen, K. B., Pien, G. C., Cousens, L. P., Salazar-Mather, T. P. (1999) Natural killer cells in antiviral defense: function and regulation by innate cytokines. Annu. Rev. Immunol. 17, 189-220.
40. Diepolder, H. M., Zachoval, R., Hoffmann, R. M., Wierenga, E. A., Santantonio, T., Jung, M. C., Eichenlaub, D., Pape, G. R. (1995) Possible mechanism involving T-lymphocyte response to non-structural protein 3 in viral clearance in acute hepatitis C virus infection. Lancet 346, 1006-1007.
41. Freeman, A. J., Pan, Y., Harvey, C. E., Post, J. J., Law, M. G., White, P. A., Rawlinson, W. D., Lloyd, A. R., Marinos, G., Ffrench, R. A. (2003) The presence of an intrahepatic cytotoxic T lymphocyte response is associated with low viral load in patients with chronic hepatitis C virus infection. J. Hepatol. 38, 349-356.
42. Lurie, Y., Nevens, F., Aprosina, Z. G., Fedorova, T. A., Kalinin, A. V., Klimova, E. A., Ilan, Y., Maevskaya, M. V., Warnes, T. W., Yuschuk, N. D., Hellstrand, K., Gehlsen, K. R. (2002) A multicentre, randomized study to evaluate the safety and efficacy of histamine dihydrochloride and interferon-α-2b for the treatment of chronic hepatitis C. J. Viral Hepat. 9, 346-353.
43. Trinchieri, G. (1989) Biology of natural killer cells. Adv. Immunol. 47, 187-376.