Phentolamine re-dosing during penile dynamic colour Doppler ultrasound: A practical method to abolish a false diagnosis of venous leakage in patients with erectile dysfunction

British Journal of Radiology

Volumn 77, Issue 923, 2004, Pages 922-926

  Gontero, P ^a,b   Sriprasad, S ^a   Wilkins, C J ^a   Donaldson, N ^a   Muir, G H ^a   Sidhu, P S ^a  

^a KING S COLLEGE HOSPITAL   (United Kingdom)

^b UNIVERSITY OF EASTERN PIEDMONT   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

PHENTOLAMINE; PROSTAGLANDIN E1; SILDENAFIL;

ADOLESCENT; ADULT; AGED; ARTICLE; CLINICAL ARTICLE; COLOR ULTRASOUND FLOWMETRY; CONTROLLED STUDY; DIAGNOSTIC ERROR; DIASTOLE; DOSE RESPONSE; ERECTILE DYSFUNCTION; HUMAN; MALE; ORGANIC IMPOTENCE; PENIS DISEASE; PENIS ERECTION; PRIAPISM; SYSTOLE; VEIN DISEASE;

ADOLESCENT; ADRENERGIC ALPHA-ANTAGONISTS; ADULT; AGED; ALPROSTADIL; BLOOD PRESSURE; DIAGNOSTIC ERRORS; DRUG THERAPY, COMBINATION; HUMANS; IMPOTENCE, VASCULOGENIC; MALE; MIDDLE AGED; MUSCLE RELAXATION; PENIS; PHENTOLAMINE; REGIONAL BLOOD FLOW; ULTRASONOGRAPHY, DOPPLER, COLOR; VASODILATOR AGENTS;

EID: 10044243457     PISSN: 00071285     EISSN: None     Source Type: Journal    
DOI: 10.1259/bjr/51141708     Document Type: Article

References (22)

1. Lavoisier P, Courtois F, Barres D, et al. Correlation between intracavernous pressure and contraction of the ischiocavernous muscle in men. J Urol 1986;136:936-41.
2. Wespes E. Diagnosis and treatment of venous impotence. Curr Opin Urol 1991;1:140-7.
3. Nehra A, Goldstein I, Pabby A, et al. Mechanisms of venous leakage: a prospective clinico-pathological correlation of corporeal function and structure. J Urol 1996;156:1320-5.
4. Rajfer J, Rosciszewski A, Mehringer M. Prevalence of corporeal venous leakage in impotent men. J Urol 1988; 140:69-74.
5. Saenz de Tejada I, Goldstein I, Krane RJ, Nerves, smooth muscles and endothelium. Review of local control of the intracavernous smooth muscle. Urol Clin N Am 1988;15: 9-15.
6. Lue TF, Zeineh SJ, Schmidt RA, et al. Physiology of penile erection. World J Urol 1983;1:194-9.
7. Karadeniz T, Ariman A, Topsakal M, et al. Value of colour Doppler sonography in the diagnosis of venous impotence. Urol Int 1995;55:143-9.
8. de Meyer JM, Thibo P. The correlation among cavernous pressure, penile rigidity and resistance index. J Urol 1998;160:63-71.
9. Mellinger BC, Fried JJ, Vaughn ED. Papaverine-induced penile blood flow acceleration in impotent men measured by duplex scanning. J Urol 1990;144:897-903.
10. Allen RP, Engel RME, Smolev JK, et al. Comparison of Duplex ultrasonography and nocturnal penile tumescence in evaluation of impotence. J Urol 1994;151:1525-32.
11. Goldstein I. Oral phentolamine: an alpha-1, alpha-2 adrenergic antagonist for the treatment of erectile dysfunction. Int J Impot Res 2000;12:75-9.
12. Meinhardt W, de la Feunte RB, Lycklama a Nijeholt AAB, et al. Prostaglandin E1 with phentolamine for the treatment of erectile dysfunction. Int J Impot Res 1996;8:5-11.
13. Sandhu D, Curless E, Dean J, et al. A double blind, placebo controlled study of intracavernosal vasoactive intestinal polypeptide and phentolamine mesylate in a novel auto-injector for the treatment of non-psychogenic erectile dysfunction. Int J Impot Res 1999;11:91-6.
14. Aversa A, Rocchietti-March M, Caprio M, Giannini D, Isidori A, Fabbri A. Anxiety-induced failure in erectile response to intracorporeal prostaglandin-E1 in non-organic male impotence: a new diagnostic approach. Int J Androl 1996;19:307-13.
15. Virag R, Frydman D, Legman M. Intracavernous injection of papaverine as diagnostic and therapeutic method in erectile failure. Angiology 1984;35:79-83.
16. Kropman RF, Schipper J, van Ostayen JA, et al. The value of increased end-diastolic velocity during penile duplex sonography in relation to pathological venous leakage in erectile dysfunction. J Urol 1992;148:314-9.
17. Akkus E, Ahci B, Ozkara H, et al. Repetition of colour Doppler ultrasonography: is it necessary. Int J Impot Res 1998;10:51-6.
18. Merckx LA, De Bruyne RM, Goes E, et al. The value of dynamic colour Duplex scanning in the diagnosis of venogenic impotence. J Urol 1992;148:318-22.
19. Bechara A, Casabe A, Cheliz G, et al. Comparative study of papaverine plus phentolamine versus prostaglandin E1 in erectile dysfunction. J Urol 1997;157:2132-8.
20. Mulhall JP, Abdel-Moneim A, Abobakr R, Goldstein I. Improving the accuracy of vascular testing in impotent men: correcting hemodynamic alterations using a vasoactive medication re-dosing schedule. J Urol 2001;166:923-6.
21. Aversa A, Bonifacio V, Moretti C, Frajese G, Fabbri A. Re-dosing of prostaglandin-E1 versus prostaglandin-E1 plus phentolamine in male erectile dysfunction: a dynamic color power Doppler study. Int J Impot Res 2000;12:33-40.
22. Montorsi F, Guazzoni G, Barbieri L, et al. The effect of intracorporeal injection plus genital and audiovisual sexual stimulation versus second injection on penile color Doppler sonography parameters. J Urol 1996;155:536-40.