Regioselectivity in the addition of vinylmagnesium bromide to heteroarylic ketones: C- versus O-alkylation

Journal of Organic Chemistry

Volumn 69, Issue 25, 2004, Pages 8903-8909

  Boga, Carla ^a   Stengel, Rayk ^a   Abdayem, Rodolphe ^a   Del Vecchio, Erminia ^a   Forlani, Luciano ^a   Todesco, Paolo E ^a  

^a UNIVERSITY OF BOLOGNA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOLS; ALKYLATION; STEREOCHEMISTRY;

PHENYL RING; REGIOCHEMISTRY;

KETONES;

(1,3 BENZOTHIAZOL 2 YL)(1,3 THIAZOL 2 YL)KETONE; 1,3 BENZOTHIAZOL 2 YL (4 CHLOROPHENYL)METHANONE; 1,3 BENZOTHIAZOL 2 YL (4 FLUOROPHENYL)METHANONE; 1,3 BENZOTHIAZOL 2 YL (4 METHOXYPHENYL)METHANONE; 1,3 BENZOTHIAZOL 2 YL (4 NITROPHENYL)METHANONE; 1,3 BENZOTHIAZOL 2 YL (PHENYL)METHANONE; 1,3 BENZOTHIAZOL 2 YL [4 (TRIFLUOROMETHYL)PHENYL]METHANONE; 2 [1 (1,3 BENZOTHIAZOL 2 YL) 1 DEUTERIO 2 PROPENYL] 1,3 BENZOTHIAZOLE; BIS(1,3 BENZOTHIAZOL 2 YL)KETONE; BIS(1,3 BENZOXAZOL 2 YL)KETONE; BIS(2,3 THIAZOL 2 YL)KETONE; BIS(N METHYLBENZIMIDAZOL 2 YL)KETONE; CARBONYL DERIVATIVE; GRIGNARD REAGENT; HALIDE; HETEROCYCLIC COMPOUND; KETONE; REAGENT; UNCLASSIFIED DRUG; VINYLMAGNESIUM BROMIDE;

ADDITION REACTION; ALKYLATION; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CHEMICAL REACTION; CHEMICAL STRUCTURE; PROTON NUCLEAR MAGNETIC RESONANCE;

ALKYLATION; HETEROCYCLIC COMPOUNDS; KETONES; MAGNESIUM; MOLECULAR CONFORMATION; MOLECULAR STRUCTURE; ORGANOMETALLIC COMPOUNDS; STEREOISOMERISM; VINYL COMPOUNDS;

EID: 10044237969     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo048948p     Document Type: Article

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