-
1
-
-
0031887318
-
Longterm prospective study of methotrexate in rheumatoid arthritis: Conclusion after 132 months of therapy
-
Weinblatt ME, Maier AL, Fraser PA, Coblyn JS. Longterm prospective study of methotrexate in rheumatoid arthritis: conclusion after 132 months of therapy. J Rheumatol 1998;25:238-42.
-
(1998)
J Rheumatol
, vol.25
, pp. 238-242
-
-
Weinblatt, M.E.1
Maier, A.L.2
Fraser, P.A.3
Coblyn, J.S.4
-
2
-
-
0035287209
-
Old and new drugs used in rheumatoid arthritis: A historical perspective. Part 1: The older drugs
-
Case JP. Old and new drugs used in rheumatoid arthritis: a historical perspective. Part 1: the older drugs. Am J Ther 2001;8:123-43.
-
(2001)
Am J Ther
, vol.8
, pp. 123-143
-
-
Case, J.P.1
-
3
-
-
0030711570
-
Methotrexate use in rheumatoid arthritis
-
O'Dell JR. Methotrexate use in rheumatoid arthritis. Rheum Dis Clin North Am 1997;23:779-96.
-
(1997)
Rheum Dis Clin North Am
, vol.23
, pp. 779-796
-
-
O'Dell, J.R.1
-
4
-
-
0027957782
-
The mechanism of action of methotrexate in rheumatoid arthritis: The search continues
-
Kremer JM. The mechanism of action of methotrexate in rheumatoid arthritis: the search continues [editorial]. J Rheumatol 1994;1:1-5.
-
(1994)
J Rheumatol
, vol.1
, pp. 1-5
-
-
Kremer, J.M.1
-
5
-
-
0031950185
-
Methotrexate in rheumatoid arthritis: An update with focus on mechanisms involved in toxicity
-
Van Ede AE, Laan RFJM, Blom HJ, De Abreu RA, van de Putte LBA. Methotrexate in rheumatoid arthritis: an update with focus on mechanisms involved in toxicity. Semin Arthritis Rheum 1998;27:277-92.
-
(1998)
Semin Arthritis Rheum
, vol.27
, pp. 277-292
-
-
Van Ede, A.E.1
Laan, R.F.J.M.2
Blom, H.J.3
De Abreu, R.A.4
Van De Putte, L.B.A.5
-
6
-
-
0030664737
-
The mechanism of action of methotrexate
-
Cronstein BN. The mechanism of action of methotrexate. Rheum Dis Clin North Am 1997;23:739-55.
-
(1997)
Rheum Dis Clin North Am
, vol.23
, pp. 739-755
-
-
Cronstein, B.N.1
-
7
-
-
84921431104
-
Folic acid and folinic acid for reducing side effects in patients receiving methotrexate for rheumatoid arthritis (Cochrane Review)
-
Oxford: Update Software; 1999
-
Ortiz Z, Shea B, Suarez-Almazor M, Moher D, Wells G, Tugwell P. Folic acid and folinic acid for reducing side effects in patients receiving methotrexate for rheumatoid arthritis (Cochrane Review). In: The Cochrane Library, Issue 2, 1999. Oxford: Update Software; 1999.
-
(1999)
The Cochrane Library
, Issue.2
-
-
Ortiz, Z.1
Shea, B.2
Suarez-Almazor, M.3
Moher, D.4
Wells, G.5
Tugwell, P.6
-
8
-
-
0033783023
-
Do patients with rheumatoid arthritis established on methotrexate and folic acid 5 mg daily need to continue folic acid supplements long term?
-
Griffith SM, Fisher J, Clarke S, et al. Do patients with rheumatoid arthritis established on methotrexate and folic acid 5 mg daily need to continue folic acid supplements long term? Rheumatology 2000;39:1102-9.
-
(2000)
Rheumatology
, vol.39
, pp. 1102-1109
-
-
Griffith, S.M.1
Fisher, J.2
Clarke, S.3
-
9
-
-
0028593942
-
Supplementation with folic acid during methotrexate therapy for rheumatoid arthritis. A double-blind, placebo-controlled trial
-
Morgan SL, Baggott JE, Vaughn WH, et al. Supplementation with folic acid during methotrexate therapy for rheumatoid arthritis. A double-blind, placebo-controlled trial. Ann Intern Med 1994;121:833-41.
-
(1994)
Ann Intern Med
, vol.121
, pp. 833-841
-
-
Morgan, S.L.1
Baggott, J.E.2
Vaughn, W.H.3
-
10
-
-
0031985832
-
The efficacy of folic acid and folinic acid in reducing methotrexate gastrointestinal toxicity in rheumatoid arthritis. A metaanalysis of randomized controlled trials
-
Ortiz Z, Shea B, Suarez-Almazor ME, Moher D, Wells GA, Tugwell P. The efficacy of folic acid and folinic acid in reducing methotrexate gastrointestinal toxicity in rheumatoid arthritis. A metaanalysis of randomized controlled trials. J Rheumatol 1998;25:36-43.
-
(1998)
J Rheumatol
, vol.25
, pp. 36-43
-
-
Ortiz, Z.1
Shea, B.2
Suarez-Almazor, M.E.3
Moher, D.4
Wells, G.A.5
Tugwell, P.6
-
11
-
-
0027285238
-
Low-dose methotrexate with leucovorin (folinic acid) in the management of rheumatoid arthritis. Results of a multicenter randomized, double-blind, placebo-controlled trial
-
Shiroky JB, Neville C, Esdaile JM, et al. Low-dose methotrexate with leucovorin (folinic acid) in the management of rheumatoid arthritis. Results of a multicenter randomized, double-blind, placebo-controlled trial. Arthritis Rheum 1993;36:795-803.
-
(1993)
Arthritis Rheum
, vol.36
, pp. 795-803
-
-
Shiroky, J.B.1
Neville, C.2
Esdaile, J.M.3
-
12
-
-
0034944211
-
Effect of folic or folinic acid supplementation on the toxicity and efficacy of methotrexate in rheumatoid arthritis: A forty-eight week, multicenter, randomized, double-blind, placebo-controlled study
-
Van Ede AE, Laan RF, Rood MJ, et al. Effect of folic or folinic acid supplementation on the toxicity and efficacy of methotrexate in rheumatoid arthritis: a forty-eight week, multicenter, randomized, double-blind, placebo-controlled study. Arthritis Rheum 2001;44:1515-24.
-
(2001)
Arthritis Rheum
, vol.44
, pp. 1515-1524
-
-
Van Ede, A.E.1
Laan, R.F.2
Rood, M.J.3
-
13
-
-
0027160604
-
Low dose leucovorin does not interfere with the efficacy of methotrexate in rheumatoid arthritis: An 8 week randomized placebo controlled trial
-
Weinblatt ME, Maier AL, Coblyn JS. Low dose leucovorin does not interfere with the efficacy of methotrexate in rheumatoid arthritis: an 8 week randomized placebo controlled trial. J Rheumatol 1993;20:950-2.
-
(1993)
J Rheumatol
, vol.20
, pp. 950-952
-
-
Weinblatt, M.E.1
Maier, A.L.2
Coblyn, J.S.3
-
14
-
-
0023945481
-
The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis
-
Arnett FC, Edworthy SM, Bloch DA, et al. The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum 1988;31:315-24.
-
(1988)
Arthritis Rheum
, vol.31
, pp. 315-324
-
-
Arnett, F.C.1
Edworthy, S.M.2
Bloch, D.A.3
-
15
-
-
0023774938
-
The clinical value of the Stanford Health Assessment Questionaire Functional Disability Index in patients with rheumatoid arthritis
-
Wolfe F, Kleinheksel SM, Cathey MA, Hawley DJ, Spitz PW, Fries JF. The clinical value of the Stanford Health Assessment Questionaire Functional Disability Index in patients with rheumatoid arthritis. J Rheumatol 1988;15:1480-8.
-
(1988)
J Rheumatol
, vol.15
, pp. 1480-1488
-
-
Wolfe, F.1
Kleinheksel, S.M.2
Cathey, M.A.3
Hawley, D.J.4
Spitz, P.W.5
Fries, J.F.6
-
16
-
-
0029044362
-
Preliminary definition of improvement in rheumatoid arthritis
-
American College of Rheumatology
-
Felson DT, Anderson JJ, Boers M, et al. American College of Rheumatology. Preliminary definition of improvement in rheumatoid arthritis. Arthritis Rheum 1995;38:727-35.
-
(1995)
Arthritis Rheum
, vol.38
, pp. 727-735
-
-
Felson, D.T.1
Anderson, J.J.2
Boers, M.3
-
17
-
-
0017261233
-
A rapid, radiochemical-ligand binding assay for methotrexate
-
Kamen BA, Takach PL, Vatev R, Caston JD. A rapid, radiochemical-ligand binding assay for methotrexate. Anal Biochem 1976;70:54-63.
-
(1976)
Anal Biochem
, vol.70
, pp. 54-63
-
-
Kamen, B.A.1
Takach, P.L.2
Vatev, R.3
Caston, J.D.4
-
18
-
-
0029898079
-
Clinical pharmacokinetics of low-dose pulse methotrexate in rheumatoid arthritis
-
Bannwarth B, Pehourcq F, Schaeverbeke T, Dehais J. Clinical pharmacokinetics of low-dose pulse methotrexate in rheumatoid arthritis. Clin Pharmacokinet 1996;30:194-210.
-
(1996)
Clin Pharmacokinet
, vol.30
, pp. 194-210
-
-
Bannwarth, B.1
Pehourcq, F.2
Schaeverbeke, T.3
Dehais, J.4
-
19
-
-
0036269584
-
Homocysteine and folate status in methotrexate-treated patients with rheumatoid arthritis
-
van Ede AE, Laan RF, Blom HJ, et al. Homocysteine and folate status in methotrexate-treated patients with rheumatoid arthritis. Rheumatology 2002;41:658-65.
-
(2002)
Rheumatology
, vol.41
, pp. 658-665
-
-
Van Ede, A.E.1
Laan, R.F.2
Blom, H.J.3
-
20
-
-
0030966942
-
Abnormal homocysteine metabolism in rheumatoid arthritis
-
Roubenoff R, Dellaripa P, Nadeau MR, et al. Abnormal homocysteine metabolism in rheumatoid arthritis. Arthritis Rheum 1997;40:718-22.
-
(1997)
Arthritis Rheum
, vol.40
, pp. 718-722
-
-
Roubenoff, R.1
Dellaripa, P.2
Nadeau, M.R.3
-
21
-
-
0033011245
-
Increased plasma levels of homocysteine and other thiol compounds in rheumatoid arthritis women
-
Hernanz A, Plaza A, Martin-Mola E, De Miguel E. Increased plasma levels of homocysteine and other thiol compounds in rheumatoid arthritis women. Clin Biochem 1999;32:65-70.
-
(1999)
Clin Biochem
, vol.32
, pp. 65-70
-
-
Hernanz, A.1
Plaza, A.2
Martin-Mola, E.3
De Miguel, E.4
-
22
-
-
0033007397
-
Influence of sulphasalazine, methotrexate, and the combination of both on plasma homocysteine concentrations in patients with rheumatoid arthritis
-
Haagsma CJ, Blom HJ, van Riel PL, et al. Influence of sulphasalazine, methotrexate, and the combination of both on plasma homocysteine concentrations in patients with rheumatoid arthritis. Ann Rheum Dis 1999;58:79-84.
-
(1999)
Ann Rheum Dis
, vol.58
, pp. 79-84
-
-
Haagsma, C.J.1
Blom, H.J.2
Van Riel, P.L.3
-
23
-
-
0025991436
-
Homocysteine levels in patients with rheumatoid arthritis treated with low-dose methotrexate
-
Morgan SL, Baggott JE, Refsum H, Ueland PM. Homocysteine levels in patients with rheumatoid arthritis treated with low-dose methotrexate. Clin Pharmacol Ther 1991;50:547-56.
-
(1991)
Clin Pharmacol Ther
, vol.50
, pp. 547-556
-
-
Morgan, S.L.1
Baggott, J.E.2
Refsum, H.3
Ueland, P.M.4
-
24
-
-
0036021124
-
Hyperhomocysteinemia in rheumatoid arthritis: Influence of methotrexate treatment and folic acid supplementation
-
Jensen OK, Rasmussen C, Mollerup F, et al. Hyperhomocysteinemia in rheumatoid arthritis: influence of methotrexate treatment and folic acid supplementation. J Rheumatol 2002;29:1615-8.
-
(2002)
J Rheumatol
, vol.29
, pp. 1615-1618
-
-
Jensen, O.K.1
Rasmussen, C.2
Mollerup, F.3
-
25
-
-
0031936472
-
Folic acid supplementation prevents deficient blood folate levels and hyperhomocysteinemia during longterm, low dose methotrexate therapy for rheumatoid arthritis: Implications for cardiovascular disease prevention
-
Morgan SL, Baggott JE, Lee JY, Alarcon GS. Folic acid supplementation prevents deficient blood folate levels and hyperhomocysteinemia during longterm, low dose methotrexate therapy for rheumatoid arthritis: implications for cardiovascular disease prevention. J Rheumatol 1998;25:441-6.
-
(1998)
J Rheumatol
, vol.25
, pp. 441-446
-
-
Morgan, S.L.1
Baggott, J.E.2
Lee, J.Y.3
Alarcon, G.S.4
-
26
-
-
0034769809
-
Changes in plasma homocysteine in arthritis patients starting treatment with low-dose methotrexate subsequently supplemented with folic acid
-
Slot O. Changes in plasma homocysteine in arthritis patients starting treatment with low-dose methotrexate subsequently supplemented with folic acid. Scand J Rheumatol 2001;30:305-7.
-
(2001)
Scand J Rheumatol
, vol.30
, pp. 305-307
-
-
Slot, O.1
-
27
-
-
0034611896
-
Methotrexate effects in patients with rheumatoid arthritis with cardiovascular comorbidity
-
Landewe RB, van den Borne BE, Breedveld FC, Dijkmans BA. Methotrexate effects in patients with rheumatoid arthritis with cardiovascular comorbidity. Lancet 2000;355:1616-7.
-
(2000)
Lancet
, vol.355
, pp. 1616-1617
-
-
Landewe, R.B.1
Van Den Borne, B.E.2
Breedveld, F.C.3
Dijkmans, B.A.4
-
28
-
-
0037132839
-
Importance of both folic acid and vitamin B12 in reduction of risk of vascular disease
-
Quinlivan EP, McPartlin J, McNulty H, et al. Importance of both folic acid and vitamin B12 in reduction of risk of vascular disease. Lancet 2002;359:227-8.
-
(2002)
Lancet
, vol.359
, pp. 227-228
-
-
Quinlivan, E.P.1
McPartlin, J.2
McNulty, H.3
-
29
-
-
0029066299
-
A quantitative assessment of plasma homocysteine as a risk factor for vascular disease. Probable benefits of increasing folic acid intakes
-
Boushey CJ, Beresford SA, Omenn GS, Motulsky AG. A quantitative assessment of plasma homocysteine as a risk factor for vascular disease. Probable benefits of increasing folic acid intakes. JAMA 1995;274:1049-57.
-
(1995)
JAMA
, vol.274
, pp. 1049-1057
-
-
Boushey, C.J.1
Beresford, S.A.2
Omenn, G.S.3
Motulsky, A.G.4
-
30
-
-
0033811792
-
Mild hyperhomocysteinemia is an independent risk factor of arterial vascular disease
-
Boers GHJ. Mild hyperhomocysteinemia is an independent risk factor of arterial vascular disease. Semin Thromb Hemost 2000;26:291-5.
-
(2000)
Semin Thromb Hemost
, vol.26
, pp. 291-295
-
-
Boers, G.H.J.1
-
31
-
-
0029131045
-
Folic acid and cyanocobalamin levels in serum and erythrocytes during low-dose methotrexate therapy of rheumatoid arthritis and psoriatic arthritis patients
-
Leeb BF, Witzmann G, Ogris E, et al. Folic acid and cyanocobalamin levels in serum and erythrocytes during low-dose methotrexate therapy of rheumatoid arthritis and psoriatic arthritis patients. Clin Exp Rheumatol 1995;13:459-63.
-
(1995)
Clin Exp Rheumatol
, vol.13
, pp. 459-463
-
-
Leeb, B.F.1
Witzmann, G.2
Ogris, E.3
-
32
-
-
2242477014
-
Lowering blood homocysteine with folic acid based supplements: Meta-analysis of randomised trials
-
Homocysteine Lowering Trialists' Collaboration
-
Lowering blood homocysteine with folic acid based supplements: meta-analysis of randomised trials. Homocysteine Lowering Trialists' Collaboration. BMJ 1998;316:894-8.
-
(1998)
BMJ
, vol.316
, pp. 894-898
-
-
-
33
-
-
0022547880
-
Methotrexate metabolism analysis in blood and liver of rheumatoid arthritis patients. Association with hepatic folate deficiency and formation of polyglutamates
-
Kremer JM, Galivan J, Streckfuss A, Kamen B. Methotrexate metabolism analysis in blood and liver of rheumatoid arthritis patients. Association with hepatic folate deficiency and formation of polyglutamates. Arthritis Rheum 1986;29:832-5.
-
(1986)
Arthritis Rheum
, vol.29
, pp. 832-835
-
-
Kremer, J.M.1
Galivan, J.2
Streckfuss, A.3
Kamen, B.4
-
34
-
-
84960560207
-
Adverse events in methotrexate-treated rheumatoid arthritis patients
-
Sandoval DM, Alarcon GS, Morgan SL. Adverse events in methotrexate-treated rheumatoid arthritis patients. Br J Rheumatol 1995;34:49-56.
-
(1995)
Br J Rheumatol
, vol.34
, pp. 49-56
-
-
Sandoval, D.M.1
Alarcon, G.S.2
Morgan, S.L.3
-
35
-
-
0036789754
-
Longitudinal measurement of methotrexate liver concentrations does not correlate with liver damage, clinical efficacy, or toxicity during a 3.5 year double blind study in rheumatoid arthritis
-
Fathi NH, Mitros F, Hoffman J, et al. Longitudinal measurement of methotrexate liver concentrations does not correlate with liver damage, clinical efficacy, or toxicity during a 3.5 year double blind study in rheumatoid arthritis. J Rheumatol 2002;29:2092-8.
-
(2002)
J Rheumatol
, vol.29
, pp. 2092-2098
-
-
Fathi, N.H.1
Mitros, F.2
Hoffman, J.3
-
36
-
-
0007907617
-
Leucovorin for methotrexate induced elevations in liver transaminases
-
Shiroky J, Neville C. Leucovorin for methotrexate induced elevations in liver transaminases [abstract]. Arthritis Rheum 1990;33 Suppl:R34.
-
(1990)
Arthritis Rheum
, vol.33
, Issue.SUPPL.
-
-
Shiroky, J.1
Neville, C.2
-
37
-
-
0030665027
-
The use of folates concomitantly with low-dose pulse methotrexate
-
Shiroky JB. The use of folates concomitantly with low-dose pulse methotrexate. Rheum Dis Clin North Am 1997;23:969-80.
-
(1997)
Rheum Dis Clin North Am
, vol.23
, pp. 969-980
-
-
Shiroky, J.B.1
-
38
-
-
0025037994
-
The effect of folic acid supplementation on the toxicity of low-dose methotrexate in patients with rheumatoid arthritis
-
Morgan SL, Baggott JE, Vaughn WH, et al. The effect of folic acid supplementation on the toxicity of low-dose methotrexate in patients with rheumatoid arthritis. Arthritis Rheum 1990;33:9-18.
-
(1990)
Arthritis Rheum
, vol.33
, pp. 9-18
-
-
Morgan, S.L.1
Baggott, J.E.2
Vaughn, W.H.3
-
40
-
-
0025887372
-
Exacerbation of rheumatoid arthritis in patients treated with methotrexate after administration of folinic acid
-
Joyce DA, Will RK, Hoffman DM, Laing B, Blackbourn SJ. Exacerbation of rheumatoid arthritis in patients treated with methotrexate after administration of folinic acid. Ann Rheum Dis 1991;50:913-4.
-
(1991)
Ann Rheum Dis
, vol.50
, pp. 913-914
-
-
Joyce, D.A.1
Will, R.K.2
Hoffman, D.M.3
Laing, B.4
Blackbourn, S.J.5
|