Solid-phase synthesis of imidazoquinazolinone derivatives with three-point diversity

Tetrahedron

Volumn 61, Issue 3, 2005, Pages 629-635

  Kesarwani, Amit P ^a   Grover, Rajesh K ^a   Roy, Raja ^a   Kundu, Bijoy ^a  

^a CENTRAL DRUG RESEARCH INSTITUTE   (India)

Author keywords

Imidazoquinazolinone; Isothiocyanates; Solid phase methodology

Indexed keywords

1 (2 ETHYLPHENYL) 3 METHYL 1,5 DIHYDROIMIDAZO[2,1 B]QUINAZOLIN 2 ONE; 1 (2 ETHYLPHENYL) 7,8 DIMETHOXY 3 METHYL 1,5 DIHYDROIMIDAZO[2,1 B]QUINAZOLIN 2 ONE; 1 BENZYL 3 ISOPROPYL 1,5 DIHYDROIMIDAZO[2,1 B]QUINAZOLIN 2 ONE; 1 BENZYL 3 METHYL 1,5 DIHYDROIMIDAZO[2,1 B]QUINAZOLIN 2 ONE; 1 BENZYL 9 METHOXY 3 METHYL 1,5 DIHYDROIMIDAZO[2,1 B]QUINAZOLIN 2 ONE; 1 PHENYL 3 PROPYL 1,5 DIHYDROIMIDAZO[2,1 B]QUINAZOLIN 2 ONE; 1,3 DIBENZYL 1,5 DIHYDROIMIDAZO[2,1 B]QUINAZOLIN 2 ONE; 2 NITROBENZALDEHYDE; 3 BENZYL 1 (2 ETHYLPHENYL) 1,5 DIHYDROIMIDAZO[2,1 B]QUINAZOL 2 ONE; 3 BENZYL 1 PHENYL 1,5 DIHYDROIMIDAZO[2,1 B]QUINAZOLIN 2 ONE; 3 BENZYL 7,8 DIMETHOXY 1 PHENYL 1,5 DIHYDROIMIDAZO[2,1 B]QUINAZOLIN 2 ONE; 3 BENZYL 9 METHOXY 1 PHENYL 1,5 DIHYDROIMIDAZO[2,1 B]QUINAZOLIN 2 ONE; 3 ISOPROPYL 1 PHENYL 1,5 DIHYDROIMIDAZO[2,1 B]QUINAZOLIN 2 ONE; 3 METHYL 1 PHENYL 1,5 DIHYDROIMIDAZO[2,1 B]QUINAZOLIN 2 ONE; 7,8 DIMETHOXY 3 METHYL 1 PHENYL 1,5 DIHYDROIMIDAZO[2,1 B]QUINAZOLIN 2 ONE; AMINO ACID; BENZALDEHYDE DERIVATIVE; FUNCTIONAL GROUP; IMIDAZOQUINAZOLINONE DERIVATIVE; ISOTHIOCYANIC ACID DERIVATIVE; QUINAZOLINONE DERIVATIVE; THIOUREA DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CYCLIZATION; DERIVATIZATION; PRIORITY JOURNAL; REDUCTION; SOLID; STRUCTURE ANALYSIS; SYNTHESIS;

EID: 10044227303     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tet.2004.10.090     Document Type: Article

References (17)

1. S. Brase, G. Gil, and K. Knepper Bioorg. Med. Chem. 10 2002 2415 2437
2. V. Krchnak, and M.W. Holladay Chem. Rev. 102 2002 61 91
3. B. Kundu Curr. Opin. Drug Dis. Dev. 6 2003 815 826
4. A.P. Kesarwani, G.K. Srivastava, S.K. Rastogi, and B. Kundu Tetrahedron Lett. 43 2002 5579 5581
5. S.K. Rastogi, G.K. Srivastava, S.K. Singh, R. Grover, R. Roy, and B. Kundu Tetrahedron Lett. 43 2002 8327 8330
6. P. Gupta, S.K. Singh, A. Pathak, and B. Kundu Tetrahedron 58 2002 10469 10474
7. G.K. Srivastava, A.P. Kesarwani, R.K. Grover, T. Srinivasan, R. Roy, and B. Kundu J. Comb. Chem. 5 2003 769 774
8. C.M. Spencer, and R.N. Brgden Drugs 47 1994 809 822
9. M.C. Venuti, R.A. Stephenson, R. Alvarez, J.J. Bruno, and A.M. Strosberg J. Med. Chem. 31 1988 2136 2145
10. F. Kienzle, A. Kaiser, and M.S. Chodnekar Eur. J. Med. Chem. 17 1982 547 556
11. V. Krchnak, J. Smith, and J. Vagner Tetrahedron Lett. 42 2001 1627 1630
12. J. Smith, J.L. Liras, S.E. Schneider, and E.V. Anslyn J. Org. Chem 61 1996 8811 8818
13. M. Li, J. Wilson, and D.E. Portlock Tetrahedron Lett. 42 2001 2273 2275
14. A. Song, J. Marik, and K.S. Lam Tetrahedron Lett. 45 2004 2727 2730
15. A.M.M.E. Omar, N.S. Habib, and O.M. Aboulwafa Synthesis 1977 864 865
16. R.T. Wragg Tetrahedron Lett. 11 1970 3931 3932
17. T. Isobe, and T. Ishikawa J. Org. Chem. 64 1999 6984 6988