Non-invasive in-vivo measurements of photosensitizer uptake using diffuse reflectance spectroscopy

Proceedings of SPIE - The International Society for Optical Engineering

Volumn 2972, Issue , 1997, Pages 136-147

  Weersink, Robert A ^a   Hayward, Joseph E ^a   Diamond, Kevin R ^a   Patterson, Michael S ^a  

^a MCMASTER UNIVERSITY   (Canada)

Author keywords

AIPcS4; Photodynamic therapy; Photosensitizer; Reflectance spectroscopy; Tissue optics

Indexed keywords

ABSORPTION; CHARGE COUPLED DEVICES; DIGITAL CAMERAS; DISCHARGE LAMPS; FIBERS; LIGHT; LIGHT SOURCES; LIGHTING; LIVER; OPTICAL MATERIALS; PHOTOSENSITIZERS; PLASMONS; REFLECTION; SKIN; SPECTROMETERS; SPECTROMETRY; SPECTRUM ANALYSIS; TISSUE; TUMORS; TWO DIMENSIONAL; VEGETATION;

AIPCS4; CCD ARRAYS; DIFFUSE REFLECTANCE SPECTROSCOPIES; DIFFUSION MODELS; FLUOROMETRIC ASSAYS; IMAGING SPECTROMETERS; IN-VIVO; LAYERED STRUCTURES; LIVER TISSUES; MONTE CARLO; MULTILAYERED SYSTEMS; NON UNIFORMS; OPTICAL SCATTERINGS; POST MORTEM; PROBE MEASUREMENTS; REFLECTANCE SPECTROSCOPY; REFLECTANCE SPECTRUMS; SINGLE EXPOSURES; SPATIAL SEPARATIONS; SURFACE PROBES; TISSUE ABSORPTIONS; TISSUE OPTICS;

PHOTODYNAMIC THERAPY;

EID: 0942294658     PISSN: 0277786X     EISSN: None     Source Type: Conference Proceeding    
DOI: 10.1117/12.273498     Document Type: Conference Paper

References (28)

1. M.S. Patterson, B.C. Wilson, and R. Graff, "In vivo test of the photodynamic threshold dose concept in normal rat liver", Photochem. Photobiol. 51 343-349 (1990).
2. W.R. Potter, T.S. Mang and T.J. Dougherty, "The theory of photodynamic therapy dosimetry: consequences of photodestruction of sensitizer", Photochem. Photobiol. 46 97-101 (1987).
3. W.R. Potter and T.S. Mang, "Photofrin II levels by in vivo fluorescence photometry" in "Porphyin Localization and Treatment of Tumors", C.J. Gomer and D.R. Doiron, eds., Alan R. Liss, New York 177-186, (1984).
4. th Int. Photodynamic Assoc. Biennial Meeting, SPIE Proc. Vol. 2371 120-124 (1995).
5. th Int. Photodynamic Assoc. Biennial Meeting, SPIE Proc. Vol. 2371 104-108 (1995).
6. D. Braichotte, R. Bays, G. Wanieres, A. Chatelain, C. Burkhardt, H. van den Bergh, P. Monnier, M. Savary and C. Fontolliet, " Photofrin II pharmacokinetics and optical dosing in tissue" in "Photodynamic Therapy: Basic Principles and Clinical Applications", ed. B.W. Henderson, Marcel Dekker, New York 425-444 (1992).
7. M. Panjehpour, R.E. Sneed D.L. Frazier, M.A. Barnhill, S.F. O'Brien, W. Harb and B.F. Overholt, "Quantification of phthalocyanine concentration in rat tissue using laser-induced fluorescence spectroscopy", Lasers Surg. Med. 13 23-30 (1993).
8. R. Biolo, G. Jori, J.C. Kennedy, P. Nadeau, R. Pottier, E. Reddi and G. Weagle, "A comparison of fluorescence methods used in the pharmacokinetic studies of Zn(II) phthalocyanine in mice", Photochem. Photobiol. 53 113-118 (1993).
9. M.S. Patterson, B.C. Wilson, J.W. Feather, D.M. Burns, and W. Pushka, "The measurement of dihematoporphyrin ether concentration in tissue by reflectance spectrophotometry", Photochem. Photobiol. 46 337-343 (1987).
10. R.A.J. Grohenhuis, H.A. Ferwerda and J.J. TenBosch, "Scattering and absorption of turbid materials determined from reflection measurements, 1:Theory", Appl. Opt. 22 2456-2462 (1983).
11. T.J. Farrell, M.S. Patterson, and B.C. Wilson, "A diffusion theory model of spatially resolved, steady-state diffuse reflectance for the noninvasive determination of tissue optical properties in vivo" Med. Phys. 19 879-888 (1992).
12. T.J. Farrell, M.S. Patterson, M. Essenpreis and D. Bocker, "A comparison of the sensitivity of continuous wave and frequency domain systems to changes in the absorption and scattering coefficients of tissue", Proceedings of the Second Topical Meeting on Advances in Optical Imaging and Photon Migration", Optical Society of America, 169-174 (1996).
13. B.C. Wilson, T.J. Farrell, and M.S. Patterson, "An optical fiber-based diffuse reflectance spectrometer for non-invasive investigation of photodynamic sensitizers in vivo" in "Future Directions and Applications in Photodynamic Therapy", ed. C.J. Gomer, SPIE, Bellingham 219-232 (1990).
14. 14M.S. Patterson, J.E. Hayward, T.J. Farrell and B.C. Wilson, "A general purpose instrument for PDT dosimetry" in "Proceedings of the Fifth Biennial Meeting of the International Photodynamic Association", SPIE Proc. 2371 477-48 1 (1995).
15. T.J. Farrell, M.S. Patterson, J.E. Hayward and B.C. Wilson, "A CCD and neural network based instrument for the noninvasive determination of tissue optical properties in vivo" SPIE Proc. 2135 "Advances in Laser and Light Spectroscopy to Diagnose Cancer and Other Diseases", SPIE, Bellingham, 117-128 (1994).
16. M.G. Nichols, E.L. Hull and T.H. Foster, "Design and testing of a white light steady-state diffuse reflectance spectrometer for determination of optical properties of highly scattering systems", Appl. Opt. 36 93-104 (1997).
17. L.Lilge, C. O'Carroll, and B.C. Wilson, "Photosensitizer quantification for ex vivo tissue samples: A tissue solubilization technique" (1996). J. Photochem. Photobiol., in press.
18. C.J. Tralau, A.J. MacRobert, P.D. Coleridge-Smith, H. Barr & S.G. Bown, "Photodynamic therapy with phthalocyanine sensitisation: quantitative studies in a transplantable rat fibrosarcoma" Br. J. Cancer, 55 389-395 (1987).
19. S.G. Bown, C.J. Tralau, P.D. Coleridge-Smith, D. Akdemir & T.J. Wieman, "Photodynamic therapy with porphyrin and phthalocyanine sensitisation: quantitative studies in normal rat fibrosarcoma" Br. J. Cancer, 54 43-52 (1986).
20. W.S. Chan, J.F. Marshall, G.Y.F. Lam & I.R. Hart, "Tissue uptake distribution and potency of the photoactivatable dye chioroaluminum sulfonated phthalocyanine in mice bearing transplantable tumors" Cancer Research, 48 3040-3044 (1988).
21. Becton Dickson, notes supplied with ICG (1990).
22. M.S. Patterson and B.W. Pogue, "Mathematical model for time-resolved and frequency domain fluorescence spectrsocopy in biological tissues" Appl. Optics 33 1963-1974 (1994).
23. A. Kienle, L. Lilge, M. S. Patterson, R. Hibst, R. Steiner, and Brian C. Wilson, "Spatially resolved absolute diffuse reflectance measurements for noninvasive determination of the optical scattering and absorption coefficients of biological tissue" Appl. Opt. 35 2304-2314 (1996).
24. W. Cheong, S.A. Prahl, and A.J. Welch, "A review of the optical properties of biological tissues," IEEE J. Quantum Electron. 26 2166-2185 (1990).
25. F. Bevilacqua, P. Marquet, C Depeursinge, and E.B. de Haller, "Determination of reduced scattering and absorption coefficients by a single charge-coupled device array measurement, part II: measurements on biological tissues" Optical Engineering 34 2064-2069 (1995).
26. B. W. Pogue & M.S. Patterson, "Error Assessment of a Wavelength Tunable Frequency Domain System for Non-invasive Tissue Spectroscopy", J. Biomedical Optics, 1 (1996) 311.
27. M.S. Patterson, S.A. Andersson-Engels, B.C. Wilson, E.K. Osei, "Absorption spectroscopy in tissue-simulating materials: a theoretical and experimental study of photon paths", Appl. Opt. 34 22-30 (1995).
28. M. Rosen-Zvi and H. Taitelbaum, "Frequency-Domain Photon Migration in Two-Layered Tissues", in OSA TOPS. On Biomedical Optical Spectrsocopy and Diagnositics, Vol. 3, eds. B. Sevick and D, Benaron, 101-104 (1996).