The treatment of acute lymphoblastic leukaemia in the elderly

Leukemia and Lymphoma

Volumn 45, Issue 1, 2004, Pages 117-123

  Pagano, Livio ^a   Mele, Luca ^a   Trapè, Giulio ^a   Leone, Giuseppe ^a  

^a CATHOLIC UNIVERSITY   (Italy)

Author keywords

Acute lymphoblastic leukaemia; Elderly patients; Prognostic factors

Indexed keywords

ALPHA INTERFERON; ANTHRACYCLINE; ASPARAGINASE; CYCLOPHOSPHAMIDE; CYTARABINE; DAUNORUBICIN; DOXORUBICIN; IMATINIB; MERCAPTOPURINE; METHOTREXATE; METHYLPREDNISOLONE; MITOXANTRONE; PREDNISONE; RITUXIMAB; STEROID; VINCRISTINE;

ACUTE LYMPHOBLASTIC LEUKEMIA; ADULT; AGED; BLOOD TOXICITY; CANCER COMBINATION CHEMOTHERAPY; CLINICAL TRIAL; DATA ANALYSIS; DRUG TOLERABILITY; GERIATRIC CARE; HEART DISEASE; HUMAN; INFECTION; MEDICAL DECISION MAKING; MEDICAL LITERATURE; PRIORITY JOURNAL; PROGNOSIS; PROSPECTIVE STUDY; RETROSPECTIVE STUDY; REVIEW; TREATMENT PLANNING;

AGED; CLINICAL TRIALS; HUMANS; LEUKEMIA, LYMPHOCYTIC, ACUTE; PROGNOSIS; RETROSPECTIVE STUDIES;

EID: 0842322919     PISSN: 10428194     EISSN: None     Source Type: Journal    
DOI: 10.1080/1042819031000139648     Document Type: Review

References (34)

1. Sandler, D.P. and Ross, J.A. (1997) "Epidemiology of acute leukemia in children and adults", Seminars in Oncology 24, 3-16.
2. Taylor, P.R.A., Reid, M.M., Bown, N., Hamilton, P.J. and Proctor, S.J. (1992) "Acute lymphoblastic leukemia in patients aged 60 years and over: a population-based study of incidence and outcome", Blood, 80, 1813-1817.
3. Bernabei, R., Venturiero, V., Tarsitani, P. and Gambassi, G. (2000) "The comprehensive geriatric assessment: when, where, how", Critical Reviews in Oncology/Hematology, 33, 45-56.
4. Taylor, P.R.A., Reid, M.M. and Proctor, S.J. (1994) "Acute lymphoblastic leukaemia in the elderly", Leukemia and Lymphoma, 13, 373-380.
5. Kantarjian, H.M., O'Brien, S., Smith, T., Estey, E.H., Beran, M., Preti, A., Pierce, S. and Keating, M.J. (1994) "Acute lymphocytic leukaemia in the elderly: characteristics and outcome with the vincristine-adriamycin-dexamethasone (VAD) regimen", British Journal of Haematology, 88, 94-100.
6. Pui, C.H. and Evans, W.E. (1998) "Acute lymphoblastic leukaemia", New England Journal of Medicine, 339, 605-615.
7. Delannoy, A., Ferrant, A., Bosly, A., Chatelain, C., Doyen, C., Martiat, P., Michaux, J.L. and Sokal, G. (1990) "Acute lymphoblastic leukemia in the elderly", European Journal of Haematology, 45, 90-93.
8. Spath-Schwalbe, E., Heil, G. and Heimpel, H. (1994) "Acute lymphoblastic leukemia in patients over 59 years of age. Experience in a single center over a 10-year period", Annals of Hematology, 69, 291-296.
9. Ferrari, A., Annino, L., Crescenzi, S., Romani, C. and Mandelli, F. (1995) "Acute lymphoblastic leukemia in the elderly: results of two different treatment approaches in 49 patients during a 25-year period", Leukemia, 9, 1643-1647.
10. Bassan, R., Di Bona, E., Lerede, T., Pogliani, E., Rossi, G., D'Emilio, A., et al. (1996) "Age-adapted moderate-dose induction and flexible outpatient postremission therapy for elderly patients with acute lymphoblastic leukaemia", Leukemia and Lymphoma, 22, 295-301.
11. Legrand, O., Marie, J.P., Marjanovic, Z., Cadiou, M., Blanc, C., Ramond, S., et al. (1997) "Prognostic factors in elderly acute lymphoblastic leukaemia", British Journal of Haematology, 97, 596-602.
12. Mandelli, F., Annino, L., Vegna, M.L., Ferrari, A., Di Raimondo, F., Invernizzi, R., et al. (1997) "Treatment of acute lymphoblastic leukemia in the elderly: result of the GIMEMA ALL 0288 > 60 years trial". In Acute Leukemias VI. Prognostic factors and treatment strategies, edited by Buchner et al. 688-694.
13. Delannoy, A., Sebban, C., Cony-Makhoul, P., Cazin, B., Cordonnier, C., Bouabdallah, R., et al. (1997) "Age-adapted induction treatment of acute lymphoblastic leukemia in the elderly and assessment of maintenance with interferon combined with chemotherapy. A multicentric prospective study in forty patients", Leukemia, 11, 1429-1434.
14. Nagura, E., Minami, S., Nagata, K., Morishita, Y., Takeyama, H., Sao, H., et al. (1999) "Analysis of elderly patients, aged 60 years old or over, with acute lymphoblastic leukaemia", Nippon Ronen Igakkai Zasshi, 36, 52-58.
15. Pagano, L., Mele, L., Casorelli, L, Fianchi, L., Di Febo, A. and Leone, G. (2000) "Acute lymphoblastic leukemia in the elderly. A twelve-year single center, retrospective study", Haematologica, 85(12), 1327-1329.
16. Thomas, X., Olteanu, N., Charrin, C., Lheritier, V., Magaud, J.P. and Fiere, D. (2001) "Acute Lymphoblastic Leukemia inthe elderly: the Edouard Herriot Hospital experience", American Journal of Hematology, 67, 73-83.
17. Yenerel, M.N., Atamer, T., Yavuz, A.S., Kucukkaya, R., Besisik, S., Aktan, M., et al. (2002) "Myeloid antigen expression provides favorable outcome in patients with adult acute lymphoblastic leukemia: a single-center study", Annals of Hematology, 81, 498-503.
18. Kantarjian, H.M., O'Brien, S., Smith, T.L., Cortes, J., Giles, F.J., Beran, M., et al. (2000) "Results of treatment with hyper-CVAD, a dose-intensive regimen, in adult acute lymphocytic leukemia", Journal of Clinical Oncology, 18, 547-561.
19. Secker-Walker, L.M., Prentice, H.G., Durrant, J., Richards, S., Hall, E. and Harrison, G. (1997) "Cytogenetics adds independent prognostic information in adults with acute lymphoblastic leukaemia on MRC trial UKALL XA", MRC Adult Leukaemia Working Party, British Journal of Haematology, 97, 937-938.
20. Weztler, M., Dodge, R.K., Mròzek, K., Carroll, A.J., Tantravahi, R., Block, A.M.W., et al. (1999) "Prospective karyotype analysis in adult acute lymphoblastic leukemia: the Cancer and Leukemia Group B Experience", Blood, 93, 3983-3993.
21. Coso, D., Cazin, B., Thomas, X., Boiron, J.M., Huguet, F., Zerazhi, H., et al. For The LALA Group, Hopital E. Herriot, Lyon, France. (2001) "Characteristics of Philadelphia-positive acute lymphocytic leukaemia (Ph + ALL) in the elderly", The American Society of Hematology, Orlando, Florida, 7-11 December 2001. Abstract 1347.
22. Anonymous (1996) "Cytogenetic abnormalities in adult acute lymphoblastic leukemia: correlations with hematologic findings outcome. A collaborative study of the Group francais de Cytogenetique Hematologique", Blood, 87, 3135-3142.
23. Mandelli, F., Annino, L., Vegna, M.L., Camera, A., Ciolli, S., Deplano, W., et al. (1992) "GIMEMA 0288: a multicentric study on adult acute lymphoblastic leukemia. Preliminary results", Leukemia, 6(Suppl 2), 182-185.
24. Hussein, K.K., Dahlberg, S., Head, D., Waddell, C.C., Dabich, L., Weick, J.K., et al. (1989) "Treatment of acute lymphoblastic leukemia in adults with intensive induction, consolidation, and maintenance chemotherapy", Blood, 73, 57-63.
25. Hoelzer, D., Thiel, E., Loffler, H., Bodenstein, H., Plaumann, L., Buchner, T., et al. (1984) "Intensified therapy in acute lymphoblastic and acute undifferentiated leukemia in adults", Blood, 64, 38-47.
26. Delannoy, A., Cazin, B., Thomas, X., Bouabdallah, R., Boiron, J.M., Huguet, F., et al. (2002) "Treatment of acute lymphoblastic leukemia in the elderly: an evaluation of interferon alpha given as a single agent after complete remission", Leukemia and Lymphoma, 43, 75-81.
27. Offidani, M., Corvatta, L., Malerba, L., Mele, A., Catarini, M. and Leoni, P. (2000) "High-dose Daunorubicin as liposomal compound in patients with ALL older than 60 years", The American Society of Hematology, Blood, vol. 96, 11, Abstract 4650.
28. Zilvassy, S.J. and Cory, S. (1993) "Phenotypic and functional characterization of competitive long-term repopulating hematopoietic stem cells enriched from 5-fluorouracil-treated murine marrow", Blood, 81, 2310-2320.
29. Zhou, D.C., Hoang-Ngoc, L., Delmer, A., Faussat, A.M., Russo, D., Zittoun, R. and Marie. J.P. (1994) "Expression of resistance genes in acute leukemia", Leukemia and Lymphoma, 13(Suppl 1), 27-30.
30. Schiedlmeier, B., Schilz, A.J., Kuhlcke, K., Laufs, S., Baum, C., Zeller, W.J., et al. (2002) "Multidrug resistance 1 gene transfer can confer chemoprotection to human peripheral blood progenitor cells engrafted in immunodeficient mice", Human Gene Therapy, 20, 233-242.
31. Cortes, J., O'Brien, S., Estey, E., Giles, F., Keating, M. and Kantarjian, H. (1999) "Phase I study of liposomal daunorubicin in patients with acute leukaemia", Investigative New Drugs, 17, 81-87.
32. Tafuri, A., Amadori, S., Ferrara, F. et al. for the GIMEMA Cooperative Study Group. (1999) "A pilot GIMEMA study of liposomal daunorubicin plus cytosine arabinoside for elderly patients with acute myeloid leukaemia", Blood, 94(Suppl 1), abstr 2270.
33. Estey, E. (1998) "Hematopoietic growth factors in the treatment of acute leukaemia", Current Opinion in Oncology, 10, 23-30.
34. Thomas, D.A., Cortes, J., Giles, F., O'Brien, S., Faderl, S., Koller, C., et al. (2001) "The modified Hyper-CVAD regimen in newly diagnosed adult acute lymphoblastic leukemia (ALL)", American Society of Hematology, Orlando-Florida, 7-11 December, 2001 (Abstr 2474).