Large Shifts in Pathogen Virulence Relate to Host Population Structure

Science

Volumn 303, Issue 5659, 2004, Pages 842-844

  Boots, M ^a   Hudson, P J ^b   Sasaki, A ^c  

^a UNIVERSITY OF SHEFFIELD   (United Kingdom)

^b PENNSYLVANIA STATE UNIVERSITY   (United States)

^c KYUSHU UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

DISEASES; IMMUNOLOGY; POPULATION STATISTICS; VIRUSES;

VIRULENCE;

PATHOLOGY;

EVOLUTION; PATHOGEN; POPULATION STRUCTURE; VIRAL DISEASE; VIRULENCE;

ARTICLE; CALICIVIRUS; CONTROLLED STUDY; IMMUNITY; MOLECULAR DYNAMICS; MOLECULAR EVOLUTION; NONHUMAN; POPULATION STRUCTURE; PRIORITY JOURNAL; VIRUS CELL INTERACTION; VIRUS RECOMBINATION; VIRUS TRANSMISSION; VIRUS VIRULENCE;

ANIMALS; CALICIVIRIDAE INFECTIONS; COMMUNICABLE DISEASES; DISEASE SUSCEPTIBILITY; EPIDEMIOLOGY, MOLECULAR; EVOLUTION; HEMORRHAGIC DISEASE VIRUS, RABBIT; HUMANS; IMMUNITY, ACTIVE; MATHEMATICS; MODELS, BIOLOGICAL; MUTATION; RECOMBINATION, GENETIC; VIRULENCE;

CALICIVIRIDAE; ORYCTOLAGUS CUNICULUS; RABBIT HEMORRHAGIC DISEASE VIRUS; RNA VIRUSES;

EID: 0842309866     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.1088542     Document Type: Article

References (12)

1. E. Levy, H. Fischetti, The New Killer Diseases (Crown, New York, 2003).
2. S. J. Schrag, P. Wiener, Trends Ecol. Evol. 10, 319 (1995).
3. R. M. May, R. M. Anderson, Proc. R. Soc. London Ser. B 219, 281 (1983).
4. R. M. Anderson, R. M. May, Parasitology 85, 411 (1982).
5. D. A. Rand, M. Keeling, H. B. Wilson, Proc. R. Soc. London Ser. B 259, 55 (199S).
6. Y. Haraguchi, A. Sasaki, J. Theoret. Biol. 203, 85 (2000).
7. M. Boots, A. Sasaki, Proc. R. Soc. London Ser. B 266, 1933 (1999).
8. S. P. Ellner, J. Theoret. Biol. 210, 435 (2001).
9. P. J. White, R. A. Norman, R. C. Trout, E. A. Gould, P. J. Hudson, Proc. R. Soc. London Ser. B 356, 1087 (2001).
10. S. R. Moss et al., J. Gen. Virol. 83, 2461 (2002).
11. S. R. Moss et al., in preparation.
12. We acknowledge R. Trout, P. White, N. Forrester, E. Gould, and S. Moss for fruitful discussions and insight. M.B. is an Natural Environmental Research Council Advanced Postdoctoral Fellow.