An audit of biological monitoring of industrial lead workers by a UK laboratory over a 2-year period

Annals of Clinical Biochemistry

Volumn 41, Issue 1, 2004, Pages 65-71

  Allen, K R ^a   Newton, K E ^a  

^a LEEDS TEACHING HOSPITALS NHS TRUST   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

HEMOGLOBIN; LEAD; PROTOPORPHYRIN ZINC;

ADULT; ARTICLE; BIOLOGICAL MONITORING; CONTROLLED STUDY; CORRELATION ANALYSIS; ENVIRONMENTAL EXPOSURE; FEMALE; HEALTH SURVEY; HUMAN; INDUSTRIALIZATION; LABORATORY TEST; LEAD BLOOD LEVEL; LEAD POISONING; MAJOR CLINICAL STUDY; MALE; MEDICAL ASSESSMENT; MEDICAL AUDIT; PRIORITY JOURNAL; SEX DIFFERENCE; STATISTICAL SIGNIFICANCE; UNITED KINGDOM; WORKER;

CHEMICAL INDUSTRY; ENVIRONMENTAL MONITORING; FEMALE; GREAT BRITAIN; HEMOGLOBINS; HUMANS; LEAD; MALE; OCCUPATIONAL EXPOSURE; PROTOPORPHYRINS; SEX FACTORS; TIME FACTORS;

EID: 0842308200     PISSN: 00045632     EISSN: None     Source Type: Journal    
DOI: 10.1258/000456304322664735     Document Type: Article

References (18)

1. Control of Lead at Work Regulations 2002. Statutory Instrument 2002 No. 2676. London: HMSO
2. Health and Safety Executive. Exposure to Lead at Work. Blood-lead Levels of Workers Exposed to Lead at Work in Great Britain, 1996/ 97-2000/01. London: Health and Safety Executive, 2002
3. Sakai T. Biomarkers of lead exposure. Ind Health 2000; 38: 127-42
4. Lamola AA, Joselow M, Yamane T. Zinc protoporphyrin (ZPP): a simple, sensitive fluorimetric screening test for lead poisoning. Clin Chem 1975; 21: 93-7
5. Grandjean P. Occupational lead exposure in Denmark: screening with the haematofluorometer. Br J Ind Med 1979; 36: 52-8
6. Fell GS. Lead toxicity: problems of definition and laboratory evaluation. Ann Clin Biochem 1984; 21: 453-60
7. Nelson JC, Westwood M, Allen KR, Newton KE, Barth JH. The ratio of erythrocyte zinc-protoporphyrin to protoporphyrin IX in disease and its significance in the mechanism of lead toxicity on haem synthesis. Ann Clin Biochem 1998; 35: 422-6
8. Grandjean P, Lintrup J. Erythrocyte Zn-protoporphyrin as an indicator of lead exposure. Scand J Clin Lab Invest 1978; 38: 669-75
9. Grandjean P, Jorgensen PJ, Viskum S. Temporal and inter-individual variation in erythrocyte zinc protoporphyrin in lead exposed workers. Br J Ind Med 1991; 48: 254-7
10. Hershko C, Konijn AM, Link G, Moreb J, Grauer F, Weissenberg E. Combined use of zinc protoporphyrin (ZPP), mean corpuscular volume and haemoglobin measurements for classifying microcytic RBC disorders in children and young adults. Clin Lab Haematol 1985; 7: 259-69
11. Jensen BM, Sando SH, Grandjean P, Wiggers P, Dalhoj J, Screening with zinc protoporphyrin for iron deficiency in non-anaemic female blood donors. Clin Chem 1990; 36: 846-8
12. Siegel RM, LaGrone DH. The use of zinc protoporphyrin in screening young children for iron deficiency. Clin Paediatr 1994; 33: 473-9
13. Hwang YF, Stickland GT, Chang NK, Beckner WM. Chronic industrial exposure to lead in 63 subjects. Clinical and erythrokinetic findings. Southeast Asian J Trop Med Public Health 1976; 7: 559-68
14. Spriewald BM, Rascu A, Schaller KH, Angerer J, Kalden JR, Harrer T. Lead induced anaemia due to traditional Indian medicine: a case report. Occup Environ Med 1999; 56: 282-3
15. Sixel-Dietrich F, Doss M, Pfeil CH, Solcher H. Acute lead intoxication due to intravenous injection. Hum Toxicol 1985; 4: 301-9
16. Mitchell-Heggs CA, Conway M, Cassar J. Herbal medicine as a cause of combined lead and arsenic poisoning. Hum Exp Toxicol 1990; 9: 195-6
17. Baker EL, Landrigan PJ, Barbour AG, Cox DH, Folland DS, Ligo RN, et al. Occupational lead poisoning in the United States: clinical and biochemical findings related to blood lead levels. Br J Ind Med 1979; 36: 14-22
18. Froom P, Kristal-Boneh E, Benbassat J, Ashkanazi R, Ribak J. Lead exposure in battery-factory workers is not associated with anaemia. J Occup Environ Med 1999; 41: 120-3