Cytotoxic oleanane triterpenoids from the rhizomes of Astilbe chinensis (Maxim.) Franch. et Savat.

Journal of Ethnopharmacology

Volumn 90, Issue 2-3, 2004, Pages 261-265

  Sun, Hong Xiang ^a,b   Ye, Yi Ping ^c   Pan, Yuan Jiang ^a  

^a ZHEJIANG UNIVERSITY   (China)

^b ZHEJIANG UNIVERSITY   (China)

^c INSTITUTE OF MATERIA MEDICA   (China)

Author keywords

Apoptosis; Astilbe chinensis; Cytotoxic activity; Rhizomes; Saxifragaceae; Triterpenoids

Indexed keywords

3BETA ACETOXYOLEAN 12 EN 27 OIC ACID; 3BETA HYDROXYOLEAN 12 EN 27 OIC ACID; 3BETA HYDROXYURS 12 EN 27 OIC ACID; 3BETA,6BETA DIHYDROXYOLEAN 12 EN 27 OIC ACID; CYTOTOXIC AGENT; OLEANOLIC ACID DERIVATIVE; TRITERPENOID; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; ASTILBE CHINENSIS; BIOASSAY; COLUMN CHROMATOGRAPHY; CONTROLLED STUDY; DOSE RESPONSE; DRUG CYTOTOXICITY; DRUG ISOLATION; DRUG PURIFICATION; DRUG STRUCTURE; FRACTIONATION; HUMAN; HUMAN CELL; MEDICINAL PLANT; PROTON NUCLEAR MAGNETIC RESONANCE; RHIZOME; STRUCTURE ANALYSIS;

ASTILBE CHINENSIS;

EID: 0842307100     PISSN: 03788741     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jep.2003.10.003     Document Type: Article

References (9)

1. Chen S.-Y., Chen C.-H. Influences of melatonin on the growth of HeLa cells. Journal of Chinese Pharmaceutical Sciences. 11:2002;48-51.
2. Chen P.-F., Lai P.-F., Zhang P., Chen L.-L. Antineoplastic activity of Heiji (rhizome of Astilbe Chinensis). China Journal of Chinese Materia Medica. 21:1996;302-303.
3. Fatope M.-O., Zeng L., Ohayaga J.-E., Shi G., Mclaughlin J.-L. Selectively cytotoxic diterpenes from Euphorbia poisonii. Journal of Medicinal Chemistry. 39:1996;1005-1008.
4. Fei X.-F., Wang B.-X., Tashiro S., Li T.-J., Ma J.-S., Ikejima T. Apoptotic effects of ginsenoside Rh2 on human malignant melanoma A375-S2 cells. Acta Pharmacologica Sinica. 23:2002;315-322.
5. Nagai M., Izawa K., Inoue T. Studies on the constituents of Saxifragaceous plants. I. Two triterpene acids of peltoboykinia tellimodes (Maxim.). Hara Chemical and Pharmaceutical Bulletin. 17:1969;1438-1443.
6. Pan J.-T. A study on the genus Astilbe (Saxifragaceae) in China. Acta Phytotaxonomica Sinica. 23:1985;432-443.
7. Pan J.-T. A study on the tribe Astilbeae Miq. (Saxifragaceae). Acta Phytotaxonomica Sinica. 33:1995;390-402.
8. Sun H.-X., Ye Y.-P., Yang K. Studies on the chemical constituents in Rhizoma Astilbe Chinensis. China Journal of Chinese Materia Medica. 27:2002;751-754.
9. Takahashi K., Kanayama K., Tanabe Y., Takani M. Studies on the constituents of medicinal plants. XI. Constituents of the roots of Astilbe thunbergii Miquel var. congests H. Boissieu. Chemical and Pharmaceutical Bulletin. 20:1972;2106-2111.