Estrogen Induces CCN5 Expression in the Rat Uterus in Vivo

Endocrinology

Volumn 145, Issue 2, 2004, Pages 976-982

  Mason, Holly R ^a   Grove Strawser, Danielle ^a   Rubin, Beverly S ^a,b   Nowak, Romana A ^c   Castellot Jr , John J ^a,b  

^a TUFTS UNIVERSITY   (United States)

^b TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ESTROGEN; MESSENGER RNA; PROGESTERONE; PROTEIN; PROTEIN CCN5; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; FEMALE; GENE INDUCTION; HORMONAL REGULATION; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; MYOMETRIUM; NONHUMAN; OVARIECTOMY; PRIORITY JOURNAL; PROESTRUS; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; TISSUE DISTRIBUTION; UPREGULATION; UTERUS;

ANIMALS; ENDOMETRIUM; ESTRADIOL; ESTROGENS; FEMALE; GENE EXPRESSION REGULATION; GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASES; IMMUNOHISTOCHEMISTRY; METESTRUS; OVARIECTOMY; POLYMERASE CHAIN REACTION; PROESTRUS; PROGESTERONE; RATS; RATS, SPRAGUE-DAWLEY; REPRESSOR PROTEINS; RNA, MESSENGER; TISSUE DISTRIBUTION; UTERUS;

EID: 0842291542     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/en.2003-0823     Document Type: Article

References (32)

1. Pepe GJ, Albrecht ED 1999 Regulation of functional differentiation of the placental villous syncytiotrophoblast by estrogen during primate pregnancy. Steroids 64:624-627
2. Bagchi IC, Li Q, Cheon YP 2001 Role of steroid hormone-regulated genes in implantation. Ann NY Acad Sci 943:68-76
3. Nowak RA 1999 Fibroids: pathophysiology and current medical treatment. Baillieres Best Pract Res Clin Obstet Gynaecol 13:223-238
4. Buttram Jr VC, Reiter RC 1981 Uterine leiomyomata: etiology, symptomatology, and management. Fertil Steril 36:433-445
5. Flototto T, Djahansouzi S, Glaser M, Hanstein B, Niederacher D, Brumm C, Beckmann MW 2001 Hormones and hormone antagonists: mechanisms of action in carcinogenesis of endometrial and breast cancer. Horm Metab Res 33:451-457
6. Akhmedkhanov A, Zeleniuch-Jacquotte A, Toniolo P 2001 Role of exogenous and endogenous hormones in endometrial cancer: review of the evidence and research perspectives. Ann NY Acad Sci 943:296-315
7. Henderson BE, Feigelson HS 2000 Hormonal carcinogenesis. Carcinogenesis 21:427-433
8. Bulun SE, Gurates B, Fang Z, Tamura M, Sebastian S, Zhou J, Amin S, Yang S 2002 Mechanisms of excessive estrogen formation in endometriosis. J Reprod Immunol 55:21-33
9. Rivera-Gonzalez R, Petersen DN, Tkalcevic G, Thompson DD, Brown TA 1998 Estrogen-induced genes in the uterus of ovariectomized rats and their regulation by droloxifene and tamoxifen. J Steroid Biochem Mol Biol 64:13-24
10. Sampath D, Winneker RC, Zhang Z 2001 Cyr61, a member of the CCN family, is required for MCF-7 cell proliferation: regulation by 17β-estradiol and overexpression in human breast cancer. Endocrinology 142:2540-2548
11. Xie D, Miller CW, O'Kelly J, Nakachi K, Sakashita A, Said JW, Gornbein J, Koeffler HP 2001 Breast cancer. Cyr61 is overexpressed, estrogen-inducible, and associated with more advanced disease. J Biol Chem 276:14187-14194
12. Sampath D, Zhu Y, Winneker RC, Zhang Z 2001 Aberrant expression of Cyr61, a member of the CCN (CTGF/Cyr61/Cef10/NOVH) family, and dysregulation by 17β-estradiol and basic fibroblast growth factor in human uterine leiomyomas. J Clin Endocrinol Metab 86:1707-1715
13. Rageh MA, Moussad EE, Wilson AK, Brigstock DR 2001 Steroidal regulation of connective tissue growth factor (CCN2; CTGF) synthesis in the mouse uterus. Mol Pathol 54:338-346
14. Perbal B 2001 NOV (nephroblastoma overexpressed) and the CCN family of genes: structural and functional issues. Mol Pathol 54:57-79
15. Delmolino LM, Stearns NA, Castellot Jr JJ 1997 Heparin induces a member of the CCN family which has characteristics of a growth arrest specific gene. Mol Biol Cell 8:287a
16. Zhang R, Averboukh L, Zhu W, Zhang H, Jo H, Dempsey PJ, Coffey RJ, Pardee AB, Liang P 1998 Identification of rCop-1, a new member of the CCN protein family, as a negative regulator for cell transformation. Mol Cell Biol 18:6131-6141
17. Pennica D, Swanson TA, Welsh JW, Roy MA, Lawrence DA, Lee J, Brush J, Taneyhill LA, Deuel B, Lew M, Watanabe C, Cohen RL, Melhem MF, Finley GG, Quirke P, Goddard AD, Hillan KJ, Gurney AL, Botstein D, Levine AJ 1998 WISP genes are members of the connective tissue growth factor family that are up-regulated in wnt-1-transformed cells and aberrantly expressed in human colon tumors. Proc Natl Acad Sci USA 95:14717-14722
18. Lake AC, Bialik A, Walsh K, Castellot Jr JJ 2003 CCN5 is a growth arrest-specific gene that regulates smooth muscle cell proliferation and motility. Am J Pathol 162:219-231
19. Mason HR, Lake AC, Wubben JE, Nowak RA, Castellot Jr JJ, The growth arrest-specific gene CCN5 is deficient in human leiomyomas and inhibits the proliferation and motility of cultured human uterine smooth muscle cells. Mol Hum Reprod, in press
20. Inadera H, Hashimoto S, Dong HY, Suzuki T, Nagai S, Yamashita T, Toyoda N, Matsushima K 2000 WISP-2 as a novel estrogen-responsive gene in human breast cancer cells. Biochem Biophys Res Commun 275:108-114
21. Xiao LJ, Diao HL, Ma XH, Ding NZ, Kadomatsu K, Muramatsu T, Yang ZM 2002 Basigin expression and hormonal regulation in the rat uterus during the peri-implantation period. Reproduction 124:219-225
22. Sabe H, Hata A, Okada M, Nakagawa H, Hanafusa H 1994 Analysis of the binding of the Src homology 2 domain of Csk to tyrosine-phosphorylated proteins in the suppression and mitotic activation of c-Src. Proc Natl Acad Sci USA 91:3984-3988
23. Hall JM, Couse JF, Korach KS 2001 The multifaceted mechanisms of estradiol and estrogen receptor signaling. J Biol Chem 276:36869-36872
24. Kushner PJ, Agard DA, Greene GL, Scanlan TS, Shiau AK, Uht RM, Webb P 2000 Estrogen receptor pathways to AP-1. J Steroid Biochem Mol Biol 74: 311-317
25. Latinkic BV, O'Brien TP, Lau LF 1991 Promoter function and structure of the growth factor-inducible immediate early gene cyr61. Nucleic Acids Res 19: 3261-3267
26. Brigstock DR 1999 The connective tissue growth factor/cysteine-rich 61/ nephroblastoma overexpressed (CCN) family. Endocr Rev 20:189-206
27. Adesanya OO, Zhou J, Bondy CA 1996 Sex steroid regulation of insulin-like growth factor system gene expression and proliferation in primate myometrium. J Clin Endocrinol Metab 81:1967-1974
28. Matsuo H, Kurachi O, Shimomura Y, Samoto T, Maruo T 1999 Molecular bases for the actions of ovarian sex steroids in the regulation of proliferation and apoptosis of human uterine leiomyoma. Oncology 57(Suppl 2):49-58
29. Zoubine MN, Banerjee S, Saxena NK, Campbell DR, Banerjee SK 2001 WISP-2: a serum-inducible gene differentially expressed in human normal breast epithelial cells and in MCF-7 breast tumor cells. Biochem Biophys Res Commun 282:421-425
30. Saxena N, Banerjee S, Sengupta K, Zoubine MN, Banerjee SK 2001 Differential expression of WISP-1 and WISP-2 genes in normal and transformed human breast cell lines. Mol Cell Biochem 228:99-104
31. Kumar S, Hand AT, Connor JR, Dodds RA, Ryan PJ, Trill JJ, Fisher SM, Nuttall ME, Lipshutz DB, Zou C, Hwang SM, Votta BJ, James IE, Rieman DJ, Gowen M, Lee JC 1999 Identification and cloning of a connective tissue growth factor-like cDNA from human osteoblasts encoding a novel regulator of osteoblast functions. J Biol Chem 274:17123-17131
32. Brandon DD, Erickson TE, Keenan EJ, Strawn EY, Novy MJ, Burry KA, Warner C, Clinton GM 1995 Estrogen receptor gene expression in human uterine leiomyoma ta. J Clin Endocrinol Metab 80:1876-1881