Endogenous Estrogen Deficiency Reduces Proliferation and Enhances Apoptosis-Related Death in Vascular Smooth Muscle Cells: Insights from the Aromatase-Knockout Mouse

Circulation

Volumn 109, Issue 4, 2004, Pages 537-543

  Ling, Shanhong ^a   Dai, Aozhi ^a   Dilley, Rodney J ^a   Jones, Margaret ^b   Simpson, Evan ^b   Komesaroff, Paul A ^a   Sudhir, Krishnankutty ^a,c  

^a BAKER IDI HEART AND DIABETES INSTITUTE   (Australia)

^b HUDSON INSTITUTE OF MEDICAL RESEARCH   (Australia)

^c STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Apoptosis; Hormones; Muscle, smooth; Proliferation

Indexed keywords

AROMATASE; CYTOCHROME P450; DNA; ESTRADIOL; ESTROGEN RECEPTOR; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; PLATELET DERIVED GROWTH FACTOR BB; RECEPTOR PROTEIN; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; AROMATASE KNOCKOUT MOUSE; ARTERY MEDIA; ARTICLE; ATTENUATION; CELL GROWTH; CELL PROLIFERATION; CELL REGENERATION; CONTROLLED STUDY; ESTROGEN DEFICIENCY; FEMALE; KNOCKOUT MOUSE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REACTION ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SMOOTH MUSCLE FIBER; VASCULAR SMOOTH MUSCLE; WESTERN BLOTTING; WILD TYPE;

ANIMALS; AORTA; APOPTOSIS; AROMATASE; CELL DIVISION; CELLS, CULTURED; ESTRADIOL; ESTROGENS; FEMALE; MALE; MICE; MICE, KNOCKOUT; MUSCLE, SMOOTH, VASCULAR; RECEPTORS, ESTROGEN; SIGNAL TRANSDUCTION;

EID: 0842285800     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.0000109699.45186.30     Document Type: Article

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