cADPR Analogues: Effect of an Adenosine 2′- Or 3′-Methoxy Group on Conformation

Organic Letters

Volumn 6, Issue 2, 2004, Pages 233-236

  Graham, Steven M ^a   Macaya, Daniel J ^b   Sengupta, Raghuvir N ^b   Turner, Kevin B ^a  

^a ST JOHN'S UNIVERSITY   (United States)

^b Benjamin N Cardozo High School   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE DERIVATIVE; CALCIUM; CYCLIC ADENOSINE DIPHOSPHATE RIBOSE; FUNCTIONAL GROUP;

ARTICLE; CALCIUM TRANSPORT; CHEMICAL BOND; DRUG CONFORMATION; DRUG STRUCTURE; DRUG SYNTHESIS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;

ADENOSINE; CYCLIC ADP-RIBOSE; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR CONFORMATION; SOLUTIONS;

EID: 0842282125     PISSN: 15237060     EISSN: None     Source Type: Journal    
DOI: 10.1021/ol036152r     Document Type: Article

References (24)

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18. 2′).
19. S to 33° and 37° gave similar results. The number of observables can be increased if the J values change significantly with temperature, but in the limited temperature ranges studied so far cADPR and its analogues show very little variation with temperature. An extensive variable-temperature study and full pseudorotation analysis will be presented in due course.
20. Thibaudeau, C.; Chattopadhyaya, J. Stereoelectronic Effects in Nucleosides and Nucleotides and their Structural Implications; Uppsala University Press: Uppsala, Sweden, 1999; pp 19-87.
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24. 5′ appropriately.