The Therapeutic Effect of Angiotensin II Receptor Antagonist in Idiopathic Pulmonary Fibrosis

Tuberculosis and Respiratory Diseases

Volumn 55, Issue 5, 2003, Pages 478-487

  Woo, Duck Soo ^a   Seol, Won Jong ^a   Kyung, Sun Young ^a   Lim, Young Hee ^a   An, Chang Hyeok ^a   Park, Jeong Woong ^a   Jeong, Sung Hwan ^a   Lee, Jae Woong ^a  

^a Gachon University   (South Korea)

Author keywords

Angiotensin II; Angiotensin II receptor antagonist; Idiopathic pulmonary fibrosis

Indexed keywords

ACETYLCYSTEINE; AMIODARONE; ANGIOTENSIN; ANGIOTENSIN 1 RECEPTOR ANTAGONIST; ANGIOTENSIN 2 RECEPTOR ANTAGONIST; DIPEPTIDYL CARBOXYPEPTIDASE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; LOSARTAN; LOSARTAN POTASSIUM; STEROID; THEOPHYLLINE;

ADULT; AGED; ANGIOTENSIN BLOOD LEVEL; APOPTOSIS; ARTICLE; CLINICAL ARTICLE; DYSPNEA; FEMALE; HUMAN; IDIOPATHIC DISEASE; LUNG ALVEOLUS EPITHELIUM; LUNG FIBROSIS; LUNG FUNCTION TEST; MALE; OPEN LUNG BIOPSY;

EID: 0742318981     PISSN: 03780066     EISSN: None     Source Type: Journal    
DOI: 10.4046/trd.2003.55.5.478     Document Type: Article

References (31)

1. Kuhn C, McDonald JA. The roles of the myofibroblast in idiopathic pulmonary fibrosis: Ultrastructural and immunohistochemical features of sites of active extracellular matrix synthesis. Am J Pathol 1991;138:1257-65.
2. Uhal BD, Joshi I, True AL, Mundle S, Raza A, Pardo A, Selman M. Fibroblasts isolated after fibrotic lung injury induce apoptosis of alveolar epithelial cells in vitro. Am J Physiol 1995;269:L819-28.
3. Uhal BD, Joshi I, Hughes WF, Ramos C, Pardo A, Selman M. Alveolar epithelial cell death adjacent to underlying myofibroblasts in advanced fibrotic human lung. Am J Physiol 1998;275:L1192-9.
4. Wang R, Ramos C, Joshi I, Zagariya A, Pardo A, Selmon m, et al. Human lung myofibroblast-derived inducers of alveolar epithelial apoptosis identified as angiotensin peptides. Am J Physiol 1999;277:L1158-64.
5. Zheng J, Jia Y, Zhou K. A study on enzymatic activities of bronchoalveolar lavage fluid in patients with interstitial lung diseases. Zhonghua Jie He He Hu Xi Za Zhi 1998;21(2):91-3.
6. Wang R, Zagariya A, Ang E, Ibarra-Sunga O, Uhal BD. Fas-induced apoptosis of alveolar epithelial cells requires ANG II generation and receptor interaction. Am J Physiol 1999;277:L1245-50.
7. Mezzano SA, Ruiz-Ortega m, Egido J. Angiotensin II and renal fibrosis. Hypertension 2001;38:635-8.
8. Wolf G. Molecular mechanisms of angiotensin II in the kidney: emerging role in the progression of renal disease: beyond haemodynamics. Nephrol Dial Transplant 1998;13: 1131-42.
9. Noble NA, Border WA. Angiotensin II in renal fibrosis: should TGF-beta rather than blood pressure be the therapeutic target? Semin Nephrol 1997;17:455-66.
10. Ibrahim HN, Rosinberg ME, Hostetter TH. Role of the renin-angiotensin-aldosterone system in the progression of renal disease: a critical review. Semin Nephrol 1997;17:431-40.
11. Katwa LC, Campbell SE, Tyagi SC, Lee SJ, Cicila GT, Weber KT. Cultured myofibroblasts generate angiotensin peptides de novo. J Mol Cell Cardiol 1997;29:1375-86.
12. Wang R, Zagariya A, Ibarra-sunga O, Gidea C, Ang E, Deshmukh S, et al. Angiotensin II induces apoptosis in human and rat alveolar epithelial cells. Am J Physiol 1999;276: L885-9.
13. Uhal BD, Gidea C, Bargout R, Bifero A, Ibarraa Sunga O, Papp m, et al. Captopril inhibits apoptosis in human lung epithelial cell: a potential antifibrotic mechanism. Am J Physiol 1998;275:L1013-7.
14. American Thoracic Society; European Respiratory Society. American Thoracic Society/ European Respiratory Society International Multidisciplinary Consensus Classification of the Idiopathic Interstitial Pneumonias. This joint statement of the American Thoracic Society (ATS), and the European Respiratory Society (ERS) was adopted by the ATS board of directors, June 2001 and by the ERS Executive Committee, June 2001. Am J Respir Crit Care Med 2002;165:277-304.
15. American Thoracic Society. Idiopathic pulmonary fibrosis: diagnosis and treatment. International consensus statement. American Thoracic Society (ATS), and the European Respiratory Society (ERS). Am J Repir Crit Care Med 2000;161:646-64.
16. Antoniades HN, Brovo MA, Avila RE, Galanopoulos T, Neville-Golden J, Maxwell M, et al. Platelet-derived growth factor in idiopathic pulmonary fibrosis. J Clin Invest 1990;86:1055-64.
17. Kapanci Y, Desmouliere A, Pache JC, Redard M, Gabbiani G. Cytoskeletal protein modulation in pulmonary alveoar myofibroblasts during idiopathic pulmonary fibrosis. Possible role of transforming growth factor beta and tumor necrosis factor alpha. Am J Respir Crit Care Med 1995;152:2163-9.
18. Khalil N, O'Connor RN, Unruh HW, Warren PW, Flanders KC, Kemp A, et al. Increased production and immunohistochemical localization of transforming growth factor-beta in idiopathic pulmonary fibrosis. Am J Respir Cell Mol Biol 1991;5:155-62.
19. Khalil N, O'Connor RN, Flanders KC, Unruh H. TGF-beta 1, but not TGF-beta 2 or TGF-beta 3, is differentially present in epithelial cells of advanced pulmonary fibrosis: an immunohistochemical study. Am J Respir Cell Mol Biol 1996;14:131-38.
20. Selman M, Ruiz V, Cabrera S, Segura L, Ramirez R, Barrios R, et al. TIMP-1, -2, -3, and -4 in idiopathic pulmonary fibrosis. A prevailing nondegradative lung microenvironment? Am J Physiol Lung Cell Mol Physiol 2000;279:L562-74.
21. Hayashi T, Stetler-Stevenson WG, Fleming MV, Fishback N, Koss MN, Liotta LA, et al. Immunohistochemical study of metalloproteinases and their tissue inhibitors in the lungs of patients with diffuse alveolar damage and idiopathic pulmonary fibrosis. Am J Pathol 1996;149:1241-56.
22. Uhal BD. Apoptosis in lung fibrosis and repair. Chest 2002;122:293S-298S.
23. Fogo AB. The role of angiotensin II and plasminogen activator and inhibitor-1 in progressive glomerulosclerosis. Am J Kidney Dis 2000;35:179-88.
24. Marshall RP, McAnulty RJ, Laurent GJ. Angiotensin II is mitogenic for human lung fibroblasts via activation of the type 1 receptor. Am J Respir Crit Care Med 2000;161:1999-2004.
25. Uhal BD, Wang R, Laukka J, Zhuang J, Soledad-Conrad V, Filippatos G. Inhibition of amiodarone-induced lung fibrosis but not alveolitis by angiotensin system antagonists. Pharmacol Toxicol 2003;92:81-7.
26. Yamada T, Horiuchi M, Dzau VJ. Angiotensin II type 2 receptor mediates programmed cell death. Proc Natl Acad Sci USA 1996;93:156-60.
27. Hamada K. [Renal hemodynamic effect of angiotensin II type 2 receptor]. Nippon Jinzo Gakkai Shi 2001;43:28-34.
28. Lynch JP 3rd, White E, Flaherty K. Corticosteroids in idiopathic pulmonary fibrosis. Curr Opin Pulm Med 2001;7:298-308.
29. Baughman RP, Alabi FO. Nonsteroidal therapy for idiopathic pulmonary fibrosis. Curr Opin Pulm Med 2001;7:309-13.