New B7 Family Members with Positive and Negative Costimulatory Function

American Journal of Transplantation

Volumn 4, Issue 1, 2004, Pages 8-14

  Rietz, Cecilia ^a   Chen, Lieping ^a  

^a MAYO CLINIC   (United States)

Author keywords

B7 molecules; Costimulation; T cells

Indexed keywords

B7 ANTIGEN;

ANTIGEN PRESENTING CELL; AUTOIMMUNITY; CANCER IMMUNOTHERAPY; CELLULAR IMMUNITY; GRAFT REJECTION; HUMAN; IMMUNE DEFICIENCY; LYMPHOCYTE ACTIVATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; SHORT SURVEY; SIGNAL TRANSDUCTION; T LYMPHOCYTE;

ANIMALS; ANTIGENS, CD; ANTIGENS, CD80; ANTIGENS, SURFACE; APOPTOSIS REGULATORY PROTEINS; AUTOIMMUNITY; GRAFT REJECTION; HUMANS; IMMUNOSUPPRESSION; IMMUNOTHERAPY; INTERFERON TYPE II; LIGANDS; LYMPHOCYTE ACTIVATION; MICE; T-LYMPHOCYTES;

EID: 0742318928     PISSN: 16006135     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1600-6143.2003.00303.x     Document Type: Short Survey

References (48)

1. Bretcher P, Cohn M. A theory of self-nonself discrimination. Science 1970; 169: 1042-1049.
2. Lindley PS, Ledbetter JA. The role of the CD28 receptor during T cell responses to antigen. Annu Rev Immunol 1993; 11: 191-212.
3. Thompson CB, Allison JP. The emerging role of CTLA-4 as an immune attenuator. Immunity 1997; 7: 445-450.
4. Dong H, Zhu G, Tamada K, Chen L. B7-H1, a third member of the B7 family, costimulates T cell proliferation and interleukin-10 secretion. Nat Med 1999; 5: 1365-1369.
5. Dong H, Strome SE, Salomao DR et al. Tumor-associated B7-H1 promotes T cell apoptosis. A potential mechanism of immune evasion. Nat Med 2002; 8: 793-800.
6. Tamura H, Dong H, Zhu G et al. B7-H1 costimulation preferentially enhances CD28 independent T helper cell function. Blood 2001; 97: 1809-1816.
7. Yamazaki T, Akiba H, Iwai H et al. Expression of programmed death ligands by murine T cells and APC. J Immunol 2002; 169: 5538-5545.
8. Freeman GJ, Long AJ, Iwai Y et al. Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation. J Exp Med 2000; 192: 1027-1034.
9. Carter LL, Fouser LA, Jussif J et al. PD-1. PD-L inhibitory pathway affects both CD4+ and CD8+ T cells and is overcome by IL-2. Eur J Immunol 2002; 32: 634-643.
10. Wang S, Bajorath J, Flies DB, Dong H, Honjo T, Chen L. Molecular modeling and functional mapping of B7-H1 and B7-DC uncouple costimulatory function from PD-1 interaction. J Exp Med 2003; 197: 1083-1091.
11. Liu X, Gao JX, Wen J et al. B7-DC/PD-L2 promotes tumor immunity by a PD-1 independent mechanism. J Exp Med 2003; 197: 1721-1730.
12. Tseng S-Y, Otsuji M, Gorski K et al. B7-DC, a new dendritic cell molecule with potent costimulatory properties for T cells. J Exp Med 2001; 193: 839-845.
13. Shin T, Kennedy G, Gorski K et al. Cooperative B7-1/2 (CD80/CD86) and B7-DC costimulation of CD4+ T cells independent of the PD-1 receptor. J Exp Med 2003; 198: 31-38.
14. Ishida Y, Agata Y, Shibahara K, Honjo T. Induced expression of PD-1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death. EMBO J 1992; 11: 3887-3895.
15. Carreno BM, Collins M. The B7 family of ligands and its receptors: new pathways for costimulation and inhibition of immune responses. Annu Rev Immunol 2002; 20: 29-53.
16. Nishimura H, Nose M, Hiai H, Minato N, Honjo T. Development of lupus-like autoimmune diseases by disruption of the PD-1 gene encoding and ITIM motif-carrying immunoreceptor. Immunity 1999; 11: 141-151.
17. Nishimura H, Okazaki T, Tanaka Y et al. Autoimmune dilated cardiomyopathy in PD-1 receptor deficient mice. Science 2001; 291: 319-322.
18. Jeannin P, Delneste Y, Lecoanet-Henchoz S, Gauchat J-F, Ellis J, Bonnefoy J-Y. CD86 (B7-2) on human B cells: a functional role in proliferation and selective differentiation into IgE and IgG4 producing cells. J Biol Chem 1997; 272: 15613-15619.
19. Grohmann U, Orabona C, Fallarino F et al. CTLA-4-Ig regulates tryptophan catabolism in vivo. Nat Immunol 2002; 3: 1097-1101.
20. Dong H, Strome S, Matteson E et al. Costimulating aberrant T cell responses by B7-H1 autoantibodies in rheumatoid arthritis. J Clin Invest 2003; 111: 363-370.
21. Radhakrishnan S, Nguyen LT, Ciric B et al. Naturally occuring human IgM that binds B7-DC and potentiates T cell stimulation by dendritic cells. J Immunol 2003; 170: 1830-1838.
22. Ozkaynak E, Wang L, Goodearl A et al. Programmed death-1 targeting can promote allograft survival. J Immunol 2002; 169: 6546-6553.
23. Hutloff A, Dittrich AM, Beier KC et al. ICOS is an inducible T-cell co-stimulator structurally and functionally related to CD28. Nature 1999; 397: 263-266.
24. Yoshinaga SK, Whoriskey JS, Khare SD et al. T-cell so-stimulation through B7RP-1 and ICOS. Nature 1999; 402: 827-832.
25. Wang S, Zhu G, Tamada K, Chen L, Bajorath J. Ligand binding sites of inducible costimulator and high avidity mutants with improved function. J Exp Med 2002; 195: 1033-1041.
26. McAdam AJ, Chang T, Lumelsky AE et al. Mouse inducible costimulatory molecule (ICOS) expression is enhanced by CD28 costimulation and regulates differentiation of CD4+ T cells. J Immunol 2000; 165: 5035-5040.
27. Wang S, Zhu G, Chapoval AI et al. Costimulation of T cells by B7-H2, a B7-like molecule that binds ICOS. Blood 2000; 96: 2808-2813.
28. Dong C, Juedes AE, Temann UA et al. ICOS co-stimulatory receptor is essential for T cell activation and function. Nature 2001; 409: 97-101.
29. Witsch EJ, Peiser M, Hutloff A et al. ICOS and CD28 reversely regulate IL-10 on re-activation of human effector T cells with mature dendritic cells. Eur J Immunol 2002; 32: 2680-2686.
30. Ogawa S, Nagamatsu G, Watanabe M et al. Opposing effects of anti-activation-inducible lymphocye-immunomodulatory molecule/inducible costimulator antibody on the development of acute versus chronic graft-versus-host disease. J Immunol 2001; 167: 5741-5748.
31. Wallin JJ, Liang L, Bakardjiev A, Sha WC. Enhancement of CD8+ T cell responses by ICOS/B7h costimulation. J Immunol 2001; 167: 132-139.
32. Liu X, Bai XF, Wen J et al. B7H costimulates clonal expansion of, and cognate destruction of tumor cells by, CD8+ T lymphocytes in vivo. J Exp Med 2001; 194: 1339-1348.
33. Swallow MM, Wallin JJ, Sha WC. B7h, a novel costimulatory homolog of B7. 1 and B7.2, is induced by TNFa. Immunity 1999; 11: 423-432.
34. Ling V, Wu PW, Finnerty HF et al. Identification of GL50, a novel B7-like protein that functionally binds to ICOS receptor. J Immunol 1999; 164: 1653-1657.
35. Yoshinaga SK, Zhang M, Pistillo J et al. Characterization of a new human B7-related protein: B7RP-1 is the ligand to the costimulatory protein ICOS. Int Immunol 2000; 12: 1439-1447.
36. Mages HW, Hutloff A, Heuck C et al. Molecular cloning and characterization of murine ICOS and identification of B7h as ICOS ligand. Eur J Immunol 2000; 30: 1040-1047.
37. Tafuri A, Shahninian A, Bladt F et al. ICOS is essential for effective T helper cell responses. Nature 2001; 409: 105-109.
38. McAdam AJ, Greenwald RJ, Levin MA et al. ICOS is critical for CD40 mediated antibody class switching. Nature 2001; 409: 102-105.
39. Grimbacher B, Hutloff A, Schlesier M et al. Homozygous loss of ICOS is associated with adult onset common variable immunodeficiency. Nat Immunol 2003; 4: 261-268.
40. Ozkaynak E, Gao W, Shemmeri N et al. Importance of ICOS-B7RP-1 costimulation in acute and chronic allograft rejection. Nat Immunol 2001; 2: 591-596.
41. Kosuge H, Suzuki J-I, Gotoh R et al. Induction of immunologic tolerance to cardiac allograft by simultaneous blockade of inducible co-stimulator and cytotoxix T lymphocyte antigen 4 pathway. Transplantation 2003; 75: 1374-1379.
42. Guo L, Li X-K, Funeshima N et al. Prolonged survival in rat liver transplantation with mouse monoclonal antibody against an inducible costimulator (ICOS). Transplantation 2002; 73: 1027-1032.
43. Nakamura Y, Yasunami Y, Satho M et al. Acceptance of islet allografts in the liver of mice by blockade of an inducible costimulator. Transplantation 2003; 75: 1115-1118.
44. Chapoval AI, Ni J, Lau JS et al. B7-H3. A costimulatory molecule for T cell activation and IFN-g production. Nat Immunol 2001; 2: 269-274.
45. Sun M, Richards S, Prasad DV, Mai XM, Rudensky A, Dong C. Characterization of mouse and human B7-H3 genes. J Immunol 2002; 268: 6294-6297.
46. Sica GL, Choi I-H, Zhu G et al. B7-H4, a molecule of the B7 family negatively regulates T cell immunity. Immunity 2003; 18: 849-861.
47. Prasad DVR, Richards S, Mai XM, Dong C. B7S1, a novel B7 family member that negatively regulates T cell activation. Immunity 2003; 18: 863-873.
48. Watanabe N, Gavrieli M, Sedy JR et al. BTLA is a lymphocyte inhibitory receptor with similarities to CTLA-4 and PD-1. Nat Immunol 2003; 4: 670-679.