Nutraceuticals, aging, and cognitive dysfunction

Veterinary Clinics of North America - Small Animal Practice

Volumn 34, Issue 1, 2004, Pages 217-228

  Head, Elizabeth ^a   Zicker, Steven C ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b Hill's Pet Nutrition Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; ALPHA TOCOPHEROL; AMYLOID BETA PROTEIN; ANTIOXIDANT; ASCORBIC ACID; BETA CAROTENE; CANTHAXANTHIN; COPPER; COPPER ZINC SUPEROXIDE DISMUTASE; DNA; DOCOSAHEXAENOIC ACID; FREE RADICAL; ISOPROSTANE; LIPID; MANGANESE; PROSTAGLANDIN; PROTEIN; REACTIVE OXYGEN METABOLITE; SELENIUM; THIOBARBITURIC ACID REACTIVE SUBSTANCE; THIOCTIC ACID; ZINC;

AGING; ANIMAL BEHAVIOR; ANIMAL DISEASE; ANIMAL FOOD; ARTICLE; BRAIN NERVE CELL; COGNITION; COGNITIVE DEFECT; DIET SUPPLEMENTATION; DOG; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG MECHANISM; FOOD COMPOSITION; FOOD PREFERENCE; LEARNING DISORDER; MEMORY DISORDER; NEUROPSYCHOLOGICAL TEST; NONHUMAN; OXIDATIVE STRESS; TISSUE INJURY;

ANIMALIA; CANIS FAMILIARIS;

EID: 0742288759     PISSN: 01955616     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cvsm.2003.09.007     Document Type: Review

References (37)

1. AVM Association U.S. Pet pwnership and demographics sourcebook 1997 American Veterinary Medical Association Schaumburg (IL)
2. Adams B. Chan A. Callahan H. Siwak C. Tapp D. Ikeda-Douglas C. et al. Spatial learning and memory in the dog as a model of cognitive aging Behav Brain Res 108 1 2000 47-56
3. Chan A.D. Nippak P.M. Murphey H. Ikeda-Douglas C.J. Muggenburg B. Head E. et al. Visuospatial impairments in aged canines (Canis familiaris): the role of cognitive-behavioral flexibility Behav Neurosci 116 3 2002 443-454
4. Head E. Mehta R. Hartley J. Kameka A.M. Cummings B.J. Cotman C.W. et al. Spatial learning and memory as a function of age in the dog Behav Neurosci 109 1995 851-858
5. Milgram N.W. Head E. Weiner E. Thomas E. Cognitive functions and aging in the dog: acquisition of nonspatial visual tasks Behav Neurosci 108 1994 57-68
6. Ruehl W.W. Bruyette D.S. DePaoli A. Cotman C.W. Head E. Milgram N.W. et-al. Canine cognitive dysfunction as a model for human age-related cognitive decline, dementia and Alzheimer's disease: clinical presentation, cognitive testing, pathology and response to l-deprenyl therapy Prog Brain Res 106 1995 217-225
7. Ruehl W.W. Neilson J. Hart B. Head E. Bruyette D.S. Cummings B.J. Therapeutic actions of l-deprenyl in dogs: a model of human brain aging In: Goldstein D. editor. Catecholamines: bridging basic science with clinical medicine, progress in brain research 1996 p. 217-225 Elsevier New York
8. Hart B.L. Effect of gonadectomy on subsequent development of age-related cognitive impairment in dogs J Am Vet Med Assoc 219 1 2001 51-56
9. Neilson J.C. Hart B.L. Cliff K.D. Ruehl W.W. Prevalence of behavioral changes associated with age-related cognitive impairment in dogs J Am Vet Med Assoc 218 11 2001 1787-1791
10. Cummings B.J. Head E. Ruehl W.W. Milgram N.W. Cotman C.W. The canine as an animal model of human aging and dementia Neurobiol Aging 17 1996 259-268
11. Head E. Milgram N.W. Cotman C.W. Neurobiological models of aging in the dog and other vertebrate species In: Hof P. Mobbs C.V. Functional neurobiology of aging 2001 p. 457-468 Academic Press San Diego
12. Wisniewski H.M. Wegiel J. Morys J. Bancher C. Soltysiak Z. Kim K.S. Aged dogs: an animal model to study beta-protein amyloidogenesis In: Maurer P.R.K. Beckman H. editors. Alzheimer's disease. Epidemiology, neuropathology, neurochemistry and clinics 1990 p. 151-167 Springer-Verlag New York
13. Su M.-Y. Head E. Brooks W.M. Wang Z. Muggenberg B.A. Adam G.E. et al. MR imaging of anatomic and vascular characteristics in a canine model of human aging Neurobiol Aging 19 5 1998 479-485
14. Braunmuhl A. Kongophile angiopathie und senile plaques bei greisen hunden Arch Psychiatr Nervenkr 194 1956 395-414 [in German]
15. Lafora G. Neoformaciones dendriticas an las neuronas y alteraciones de la neuroglia en el perro senil Trab del Lab de Investig Biol 1 1914 [in Spanish]
16. Wisniewski H.M. Johnson A.B. Raine C.S. Kay W.J. Terry R.D. Senile plaques and cerebral amyloidosis in aged dogs Lab Invest 23 1970 287-296
17. Selkoe D.J. Amyloid beta-protein and the genetics of Alzheimer's disease J Biol Chem 271 1996 18295-18298
18. Johnstone E.M. Chaney M.O. Norris F.H. Pascual R. Little S.P. Conservation of the sequence of the Alzheimer's disease amyloid peptide in dog, polar bear and five other mammals by cross-species polymerase chain reaction analysis Brain Res Mol Brain Res 10 4 1991 299-305
19. Selkoe D.J. Bell D.S. Podlisny M.B. Price D.L. Cork L.C. Conservation of brain amyloid proteins in aged mammals and humans with Alzheimer's disease Science 235 1987 873-877
20. Colle M.-A. Hauw J.-J. Crespeau F. Uchiara T. Akiyama H. Checler F. et al. Vascular and parenchymal Aβ deposition in the aging dog: correlation with behavior Neurobiol Aging 21 2000 695-704
21. Cummings B.J. Head E. Ruehl W.W. Milgram N.W. Cotman C.W. Beta-amyloid accumulation correlates with cognitive dysfunction in the aged canine Neurobiol Learn Mem 66 1996 11-23
22. Head E. Callahan H. Muggenburg B.A. Cotman C.W. Milgram N.W. Visual-discrimination learning ability and beta-amyloid accumulation in the dog Neurobiol Aging 19 5 1998 415-425
23. Ames B.N. Shigenaga M.K. Hagen T.M. Oxidants, antioxidants, and the degenerative diseases of aging Proc Natl Acad Sci USA 90 1993 7915-7922
24. Harman D. Aging: a theory based on free radical and radiation chemistry J Gerontol 11 1956 298-300
25. Beckman K.B. Ames B.N. The free radical theory of aging matures Physiol Rev 78 2 1998 547-581
26. Joseph J.A. Denisova N. Fisher D. Bickford P. Prior R. Cao G. Age-related neurodegeneration and oxidative stress: putative nutritional intervention Neurol Clin 16 3 1998 747-755
27. Cottrell D.A. Turnbull D.M. Mitochondria and ageing Curr Opin Clin Nutr Metab Care 3 6 2000 473-478
28. Kiatipattanasakul W. Nakamura S. Kuroki K. Nakayama H. Doi K. Immunohistochemical detection of anti-oxidative stress enzymes in the dog brain Neuropathology 17 1997 307-312
29. Head E. Liu J. Hagen T.M. Muggenburg B.A. Milgram N.W. Ames B.N. et al. Oxidative damage increases with age in a canine model of human brain aging J Neurochem 82 2002 375-381
30. De Ruvo C. Amodio R. Algeri S. Martelli N. Intelangelo A. D'Ancona G.M. et al. Nutritional antioxidants as antidegenerative agents Int J Dev Neurosci 18 4-5 2000 359-366
31. Haramaki N. Stewart D.B. Aggarwal S. Ikeda H. Reznick A.Z. Packer L. Networking antioxidants in the isolated rat heart are selectively depleted by ischemia-reperfusion Free Radic Biol Med 25 3 1998 329-339
32. Liu J. Killilea D.W. Ames B.N. Age-associated mitochondrial oxidative decay: improvement of carnitine acetyltransferase substrate-binding affinity and activity in brain by feeding old rats acetyl-L-carnitine and/or R-alpha -lipoic acid Proc Natl Acad Sci USA 99 4 2002 1876-1881
33. Liu J. Head E. Gharib A.M. Yuan W. Ingersoll R.T. Hagen T.M. et al. Memory loss in old rats is associated with brain mitochondrial decay and RNA/DNA oxidation: partial reversal by feeding acetyl-L-carnitine and/or R-alpha -lipoic acid Proc Natl Acad Sci USA 99 4 2002 2356-2361
34. Milgram N.W. Zicker S.C. Head E. Muggenburg B.A. Murphey H. Ikeda-Douglas C. et al. Dietary enrichment counteracts age-associated cognitive dysfunction in canines Neurobiol Aging 23 2002 737-745
35. Dodd C, Zicker SC, Jewell DE, Lowry SR, Fritsch D, Toll PW. Effects of an investigational food on age related behavioral changes in dogs. In: Hill's European Symposium on Canine Brain Ageing. 2002. Barcelona, Spain.
36. Leonard S.W. Good C. Guggar E. Traber M.G. Improved vitamin E bioavailability from a fortified breakfast cereal as compared with a vitamin E supplement FASEB J 16 4 2002 A373-A374
37. Scallon L.J. Burke J.M. Mieler W.F. Kies J.C. Aaberg T.M. Canthaxanthine-induced retinal pigment epithelial changes in the cat Curr Eye Res 7 7 1988 687-693