Simultaneous Manifestation of Chronic Lymphocytic Leukemia (CLL) and Hairy Cell Leukemia (HCL)

American Journal of Hematology

Volumn 75, Issue 2, 2004, Pages 107-109

  Sokol, Lubomir ^a   Agosti, Steven J ^b  

^a H LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Chronic lymphocytic leukemia; Flow cytometry; Hairy cell leukemia

Indexed keywords

2 CHLOROADENOSINE; ACID PHOSPHATASE TARTRATE RESISTANT ISOENZYME; CD103 ANTIGEN; CD20 ANTIGEN; CHLORAMBUCIL; CYCLOPHOSPHAMIDE; FLUDARABINE; GLYCOPROTEIN P 15095; GRANULOCYTE COLONY STIMULATING FACTOR RECEPTOR; IMMUNOGLOBULIN KAPPA CHAIN; IMMUNOGLOBULIN LAMBDA CHAIN; INTERLEUKIN 2 RECEPTOR; PREDNISONE; RITUXIMAB;

AGED; ARTICLE; B LYMPHOCYTE; BLOOD SMEAR; CASE REPORT; CAUCASIAN; CHRONIC LYMPHATIC LEUKEMIA; FLOW CYTOMETRY; HAIRY CELL LEUKEMIA; HUMAN; LYMPHADENOPATHY; LYMPHOCYTOSIS; MALE; MONOTHERAPY; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; SPLENOMEGALY;

AGED; AGED, 80 AND OVER; ANTIBODIES, MONOCLONAL; ANTIGENS, CD; ANTINEOPLASTIC AGENTS; FEMALE; FLOW CYTOMETRY; HUMANS; IMMUNOPHENOTYPING; LEUKEMIA, HAIRY CELL; LEUKEMIA, LYMPHOCYTIC, CHRONIC; NEOPLASMS, SECOND PRIMARY; TREATMENT OUTCOME;

EID: 0742287902     PISSN: 03618609     EISSN: None     Source Type: Journal    
DOI: 10.1002/ajh.10459     Document Type: Article

References (14)

1. Catovsky D. Chronic lymphoproliferative disorders. Curr Opin Oncol 1995;7:3-11.
2. Maher VE, Gill L, Townes PL, et al. Simultaneous chronic lymphocytic leukemia and chronic myelogenous leukemia. Evidence of a separate stem cell origin. Cancer 1993;71:1993-1997.
3. Pajor L, Kereskai L, Tamaska P, Vass JA, Radvanyi G. Coexistence of chronic myeloid leukemia and hairy cell leukemia of common clonal origin. Cancer Genet Cytogenet 2002;134:114-117.
4. Saif MW, Greenberg BR. Multiple myeloma and hairy cell leukemia: a rare association or coincidence? Leuk Lymphoma 2001;42: 1043-1048.
5. Resegotti L, Pistone M, Testa D, Rua S, Coda R. Simultaneous occurrence of hairy cell leukemia and Hodgkin's disease in the same patient. Haematologica 1985;70:185.
6. Brown SA, Phillips J, Ahsan G, Slater NG. Coexistent hairy cell leukemia and chronic lymphocytic leukemia. Leuk Lymphoma 1998;30:203-209.
7. Gine E, Bosch F, Villamor N, et al. Simultaneous diagnosis of hairy cell leukemia and chronic lymphocytic leukemia/small lymphocytic lymphoma: a frequent association? Leukemia 2002;8:1454-1459.
8. Robbins BA, Ellison DJ, Spinosa JC, et al. Diagnostic application of two-color flow cytometry in 161 cases of hairy cell leukemia. Blood 1993;82:1277-1287.
9. Cornfield DB, Nelson DMM, Rimsza LM, Moller-Patti D, Braylan RC. The diagnosis of hairy cell leukemia can be established by flow cytometric analysis of peripheral blood, even in patients with low levels of circulating malignant cells. Am J Hematol 2001;67: 223-226.
10. Forsconi F, Sahota SS, Raspadori D, Mockridge CI, Lauria F, Stevenson FK. Tumor cells of hairy cell leukemia express multiple clonally related immunoglobulin isotypes via RNA splicing. Blood 2001;98:1174-1181.
11. + B cells can continue to rearrange kappa and lambda L chain gene loci. J Exp Med 1993;178:1263-1270.
12. Giardina SL, Schroff RW, Woodhouse CS, et al. Detection of two distinct malignant B cell clones in a single patient using antiidiotype monoclonal antibodies and immunoglobulin gene rearrangement. Blood 1985;66:1017-1021.
13. Miyamura K, Osada H, Yamauchi T, et al. Single clonal origin of neoplastic B-cells with different immunoglobulin light chains in a patient with Richter's syndrome. Cancer 1990;66:140-144.
14. Kawada H, Fukuda R, Yoshida M, et al. A novel variant of B-lymphoid leukemia expressing kappa/lambda light chain. Acta Haematol 1998;100:54-56.