Pharmaceutical product design using combinatorial optimization

Computers and Chemical Engineering

Volumn 28, Issue 3, 2004, Pages 425-434

  Siddhaye, S ^a   Camarda, K ^a   Southard, M ^a   Topp, E ^b  

^a UNIVERSITY OF KANSAS   (United States)

^b UNIVERSITY OF KANSAS   (United States)

Author keywords

Molecular design; Optimization

Indexed keywords

COMPUTATIONAL METHODS; DRUG PRODUCTS; LINEAR PROGRAMMING; MATRIX ALGEBRA; MOLECULES; OPTIMIZATION; SOLUBILITY;

MIXED INTEGER LINEAR PROGRAMMING (MILP);

PRODUCT DESIGN;

OCTANOL; WATER;

OPTIMIZATION; PHARMACEUTICAL INDUSTRY;

ARTICLE; CORRELATION ANALYSIS; DRUG DESIGN; MELTING POINT; PARTITION COEFFICIENT; PROCESS OPTIMIZATION; SOLUBILITY; STRUCTURE ACTIVITY RELATION;

EID: 0742287045     PISSN: 00981354     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.compchemeng.2003.08.011     Document Type: Article

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