A controlled trial of oral acyclovir for iridocyclitis caused by herpes simplex virus: The Herpetic Eye Disease Study Group

Archives of Ophthalmology

Volumn 114, Issue 9, 1996, Pages 1065-1072

  Beck, Roy W ^a  

^a JAEB CENTER FOR HEALTH RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACICLOVIR; PREDNISOLONE SODIUM PHOSPHATE; TRIFLURIDINE;

ADULT; ANTIVIRAL ACTIVITY; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CORTICOSTEROID THERAPY; DRUG EFFICACY; FEMALE; GASTROINTESTINAL SYMPTOM; HERPES SIMPLEX; HUMAN; IRIDOCYCLITIS; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; TOPICAL DRUG ADMINISTRATION; TREATMENT FAILURE; TREATMENT OUTCOME; TREATMENT PLANNING;

EID: 0742285972     PISSN: 00039950     EISSN: None     Source Type: Journal    
DOI: 10.1001/archopht.1996.01100140267002     Document Type: Article

References (42)

1. Hemmes GD. Acute anterior uveitis of unknown origin and its connection with herpes simplex. Ophthalmologica. 1968;155:300-307.
2. Martenet A-C. Aktuelle Diagnostik und Therapie der viralen Augenaffektionen. Buch Augenarzt. 1974;65(suppl):108-125.
3. Schlaegel TF Jr, O'Connor GR. Current aspects of uveitis: general considerations. Int Ophthalmol Clin. 1977;17:1-42.
4. Noor Sunba MS, Al-Awqati M, Sherriff SM. The diagnostic significance of serological screening of patients with uveitis. Acta Ophthalmol. 1988;66:709-712.
5. Haut J, Roman S, Morin Y, Monin C, Morel C. Recherche etiologique de cent dix uvéites: intêret des ponctions d'humeur aqueuse et du vitre. J Fr Ophtalmol. 1995;18:292-304.
6. Kimura SJ. Herpes simplex uveitis: a clinical and experimental study. Trans Am Ophthalmol Soc. 1962;60:440-470.
7. Pavan-Langston D, Brockhurst RJ. Herpes simplex panuveitis: a clinical report. Arch Ophthalmol. 1969;81:783-787.
8. O'Connor GR. Recurrent herpes simplex uveitis in humans. Surv Ophthalmol. 1976;21:165-170.
9. Liesegang TJ. Epidemiology of ocular herpes simplex: natural history in Rochester, Minn, 1950 through 1982. Arch Ophthalmol. 1989;107:1160-1165.
10. Thygeson P, Hogan MJ, Kimura SJ. Observations on uveitis associated with viral disease. Trans Am Ophthalmol Soc. 1957;55:333-352.
11. Ahonen R, Vannas A. Clinical comparison between herpes simplex and herpes zoster ocular infection. In: Maudgal PC, Missotten L, eds. Herpetic Eye Diseases: Proceedings of the International Symposium at the Katholieke Universiteit Leuven, Leuven, Belgium, May 17-19, 1984. Dordrecht, the Netherlands: Junk; 1985:389-392.
12. Wilhelmus KR, Gee L, Hauck WW, et al. Herpetic Eye Disease Study: a controlled trial of topical corticosteroids for herpes simplex stromal keratitis. Ophthalmology. 1994;101:1883-1896.
13. Barron BA, Gee L, Hauck WW, et al. Herpetic Eye Disease Study: a controlled trial of oral acyclovir for herpes simplex stromal keratitis. Ophthalmology. 1994; 101:1871-1882.
14. Cavara V. Le flogosi uveali da virus filtrabili. Boll Oculist 1950;29:3-28.
15. Korra AE, Mourad AS, el-Sahn ME. Isolation of herpes simplex virus from the aqueous humour in herpetic kerato-iritis. Bull Ophthalmol Soc Egypt. 1976; 69:89-93.
16. Katsnelson AB, Voinov IN, Kaplina KP. Investigations into aetiology and pathogenesis of herpetic eye diseases. Vestn Oftalmol. 1962;3:61-67.
17. Sundmacher R, Neumann-Haefelin D. Herpes-simplex-Virus-Isolierung aus dem Kammerwasser bei fokaler Iritis, Endotheliitis und landdauernder Keratitis disciformis mit Sekundarglaukom. Klin Monastsbl Augenheilkd. 1979;175:488-501.
18. Sundmacher R. Orale Acyclovir-Tharapie virologisch nachgewiesener intraokularer Herpes simplex Virus Infektionen. Klin Monatsbl Augenheilkd. 1983;183: 246-250.
19. Cavara V, Bietti GB. Herpes simplex o febrilis. In: Cavara V, ed. Le Manifestazioni Oculari delle Malattie da Virus e da Rickettsie. Bologna, Italia: Licinio Cappelli; 1952:25-103.
20. Patterson A, Somerville RG, Jones BR. Herpetic keratouveitis with herpes virus antigen in the anterior chamber. Trans Ophthalmol Soc UK. 1968;88:243-249.
21. Kaufman HE, Kanai A, Ellison ED. Herpetic iritis: demonstration of virus in the anterior chamber by fluorescent antibody techniques and electron microscopy. Am J Ophthalmol. 1971;71:465-469.
22. Bock J, Fanta D, Soltz-Szots J, Zehetbauer G, Gebhart W. Isolierung von Herpes simplex-Virus aus dem Kammerwasser eines an rezidivierender Iridocyclitis erkrankten Auges. Albrecht von Graefes Arch Klin Ophthalmol. 1972;185: 349-353.
23. Gangwar DN, Jain IS, Gupta A, Choudhury S, Paul SR. Herpetic uveitis. East Arch Ophthalmol. 1979;7:104-109.
24. Martenet AC. Herpes simplex uveitis: an experimental study. Arch Ophthalmol. 1966;76:858-865.
25. Tucker DN, Kapikian AZ. Experimental herpes simplex uveitis: the isolation of herpesvirus in an iris organ culture system. Arch Ophthalmol. 1969;82:827-829.
26. Oh JO. Primary and secondary herpes simplex uveitis in rabbits. Surv Ophthalmol. 1976;21:178-190.
27. Denis J. Immunological study of the aqueous humor in ocular herpes simplex. Mod Probl Ophthalmol. 1976;16:220-224.
28. Kijlstra A. The value of laboratory testing in uveitis. Eye. 1990;4:732-736.
29. Dussaix E, Cerqueli PM, Pontet F, Bloch-Michel E. New approaches to the detection of locally produced antiviral antibodies in the aqueous of patients with endogenous uveitis. Ophthalmologica. 1987;194:145-149.
30. Oh JO, Minasi P. Role of lymphocyte and antibody in the pathogenesis of immunemediated herpetic uveitis. Curr Eye Res. 1985;4:685-691.
31. Young LY, Foster CS, Young JD. In vivo expression of perform by natural killer cells during a viral infection: studies on uveitis produced by herpes simplex virus type 1. Am J Pathol. 1990;136:1021-1030.
32. Kasparov AA, Popova ZS. Klinicheski osobennosti i printsipy lecheniia virusnykh iridotsiklirov. Vestn Oftalmol. 1978;95:40-44.
33. Hung SO, Patterson A, Rees PJ. Pharmacokinetics of oral acyclovir (Zovirax) in the eye. Br J Ophthalmol. 1984;68:192-195.
34. Sugar J, Varnell E, Centifanto Y, Kaufman HE. Trifluorothymidine treatment of herpetic iritis in rabbits and ocular penetration. Invest Ophthalmol. 1973;12: 532-534.
35. Wilhelmus KR, Falcon MG, Jones BR. Herpetic iridocyclitis. Int Ophthalmol. 1982;4:143-150.
36. Colin J, Malet F, Chastel C. Acyclovir in herpetic anterior uveitis. Ann Ophthalmol. 1991;23:28-30.
37. Trichet C, Dussaix E, Cerqueti P, Offret H. Traitement preventif des keratites herpetiques par l'acyclovir en comprimes. J Fr Ophtalmol. 1993;16:591-593.
38. Dawson CR, Jones DB, Kaufman HE, et al. Design and organization of the herpetic eye disease study (HEDS). Curr Eye Res. 1991;10(suppl):105-110.
39. Herpetic Eye Disease Study Group. Manual of Operations, version 3.4. Spring-field, Va: National Technical Information Service; 1991. (Accession No. PB93-175453).
40. Mantel N. Evaluation of survival data and two new rank order statistics arising in its consideration. Cancer Chemother Rep. 1966;50:163-70.
41. Cox DR. Regression models and life-tables. J R Stat Soc. 1972;34:187-220.
42. Wilcoxon F. Individual comparison by ranking methods. Biometrics. 1945;1: 80-83.