Histopathology and Immunohistochemistry of Canine Distemper Virus-induced Footpad Hyperkeratosis (Hard Pad Disease) in Dogs with Natural Canine Distemper

Veterinary Pathology

Volumn 41, Issue 1, 2004, Pages 2-9

  Koutinas, A F ^a,d   Baumgartner W ^b   Tontis, D ^c   Polizopoulou, Z ^a   Saridomichelakis, M N ^a   Lekkas, S ^a  

^a ARISTOTLE UNIVERSITY OF THESSALONIKI   (Greece)

^b UNIVERSITY OF VETERINARY MEDICINE HANNOVER   (Germany)

^c UNIVERSITY OF THESSALY   (Greece)

^d NONE   (Greece)

Author keywords

Digital hyperkeratosis; Distemper virus; Dogs; Immunohistochemistry; Stratum spinosum

Indexed keywords

VIRUS ANTIGEN;

ACANTHOSIS; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CANINE DISTEMPER MORBILLIVIRUS; CLINICAL FEATURE; CONTROLLED STUDY; DERMATITIS; DISEASE DURATION; DOG DISEASE; EPITHELIUM CELL; FEMALE; FOOT PAD; HAIR FOLLICLE; HISTOPATHOLOGY; HYPERKERATOSIS; IMMUNOHISTOCHEMISTRY; MALE; MICROSCOPY; NONHUMAN; PATHOGENESIS; THICKNESS; VIRUS INFECTION;

ANIMALS; ANTIGENS, VIRAL; DISTEMPER; DISTEMPER VIRUS, CANINE; DOG DISEASES; DOGS; FOOT DERMATOSES; IMMUNOHISTOCHEMISTRY; KERATINOCYTES; KERATOSIS;

ANIMALIA; CANINE DISTEMPER VIRUS; CANIS FAMILIARIS;

EID: 0742270078     PISSN: 03009858     EISSN: None     Source Type: Journal    
DOI: 10.1354/vp.41-1-2     Document Type: Article

References (20)

1. Appel MJG, Gillespie JH: Canine distemper virus. Virol Monogr 11:1-96, 1972
2. Baumgärtner W, Örveil C, Reinacher M: Naturally occurring canine distemper virus encephalitis: distribution and expression of viral polypeptides in nervous tissues. Acta Neuropathol 78:504-512, 1989
3. Cooper LZ: Measles. In: Dermatology in General Medicine, ed. Fitzpatric TB, Eisen AZ, Wolff K, Freedberg IM, and Aysten KF, 4th ed., pp. 2516-2520. McGraw Hill, New York, NY, 1993
4. Ducatelle R, Coussement W, Hoorens J: Demonstration of canine distemper viral antigen in paraffin sections, using an unlabeled antibody-enzyme method. Am J Vet Res 41:1860-1862, 1980
5. Ek-Kommonen C, Sihvonen L, Pekkanen K, Rikula U, Nuotio L: Outbreak of canine distemper in vaccinated dogs in Finland. Vet Rec 141:380-383, 1997
6. Greene CE, Appel MJ: Canine distemper. In: Infectious Diseases of the Dog and Cat, ed. Greene CE, 2nd ed., pp. 9-22. WB Saunders, Philadelphia, PA, 1998
7. Haines DM, Martin KM, Chelack BJ, Sargent RA, Outerbridge CA, Clark EG: Immunohistochemical detection of canine distemper virus in haired skin, nasal mucosa, and footpad epithelium: a method for antemortem diagnosis of infection. J Vet Diagn Invest 11:396-399, 1999
8. Macintyre AB, Trevan DJ, Montgomerie RF: Observations on canine encephalitis. Vet Rec 49:635-644, 1948
9. Maeda H, Ozaki K, Takagi Y, Sawashima K, Narama I: Distemper skin lesions in a dog. J Vet Med A 41:247-250, 1994
10. Moritz A, Frisk A, Baumgärtner W: The evaluation of diagnostic procedures for the detection of canine distemper virus infection. Eur J Comp Anim Pract 10:37-47, 2000
11. Mylonakis MM, Koutinas AF, Plevraki KG: Current aspects on vaccines and immunization in the dog and cat. Part I. General aspects-vaccines and vaccinations in the dog. Bull Hell Vet Med Soc 50:15-24, 1999
12. Örvell C, Sheshberadaran H, Norrby E: Preparation and characterization of monoclonal antibodies directed against four structural components of canine distemper virus. J Gen Virol 66:443-456, 1985
13. Schafer KA: The cell cycle: a review. Vet Pathol 35: 461-478, 1998
14. Scott DW, Miller WH, Griffin CE: Muller and Kirk's Small Animal Dermatology, 6th ed., pp. 1-70, 517-542. WB Saunders, Philadelphia, PA, 2001
15. Shimada A, Shinya K, Awakura T, Narama I, Maeda H, Umemura T: Cutaneous papillomatosis associated with papillomavirus infection in a dog. J Comp Pathol 108: 103-107, 1993
16. Sironi G, Caniatti M, Scanziani E: Immunohistochmical detection of papillomavirus structural antigens in animal hyperplastic and neoplastic lesions. J Vet Med A 37: 760-770, 1990
17. Smith KC, Bennett M, Garrett DC: Skin lesions caused by orthopoxvirus in a dog. J Small Anim Pract 40:495-497, 1999
18. Sundberg JP, Randall EJ, Lancaster WD: Immunoperoxidase localization of papillomaviruses in hyperplastic and neoplastic epithelial lesions of animals. Am J Vet Res 45:1441-1446, 1984
19. Suter MM, Crameri FM, Olivry T, Mueller E, von Tscharner C, Jensen PJ: Keratinocyte biology and pathology. Vet Dermatol 8:67-100, 1997
20. Yager JA, Wilcock BP: Color Atlas and Text of Surgical Pathology of the Dog and Cat. Dermatopathology and Skin Tumors. Wolfe Publishing, London, UK, 1994