S-Nitrosothiol-induced rapid cytochrome c release, caspase activation and mitochondrial permeability transition in perfused heart

Biochemical Pharmacology

Volumn 66, Issue 8, 2003, Pages 1513-1519

  Jekabsone, Aiste ^a   Dapkunas, Zilvinas ^a   Brown, Guy C ^b   Borutaite, Vilmante ^b  

^a KAUNAS UNIVERSITY OF MEDICINE   (Lithuania)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

Apoptosis; DETA NO; Diethylenetriamine NO adduct; GSNO; Inducible nitric oxide synthase; iNOS; Mitochondria; Mitochondrial permeability transition; MPT; Nitric oxide; NO; Perfused heart; Respiration; S nitrosoglutathione

Indexed keywords

CASPASE; CYCLOSPORIN A; CYTOCHROME C; DIETHYLENETRIAMINE; NITRIC OXIDE; S NITROSOGLUTATHIONE; S NITROSOTHIOL; NITRIC OXIDE DONOR;

ANIMAL TISSUE; CONCENTRATION RESPONSE; CONFERENCE PAPER; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; HEART PERFUSION; MALE; MEMBRANE PERMEABILITY; MITOCHONDRIAL MEMBRANE; MITOCHONDRIAL RESPIRATION; NONHUMAN; PRIORITY JOURNAL; RAT; ANIMAL; APOPTOSIS; ARTICLE; DRUG EFFECT; HEART; METABOLISM; MITOCHONDRION; PERFUSION; PERMEABILITY; PHYSIOLOGY; WISTAR RAT;

ANIMALS; APOPTOSIS; CASPASES; CYTOCHROMES C; ENZYME ACTIVATION; HEART; MALE; MITOCHONDRIA; NITRIC OXIDE DONORS; PERFUSION; PERMEABILITY; RATS; RATS, WISTAR; S-NITROSOGLUTATHIONE; S-NITROSOTHIOLS;

EID: 0642375806     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(03)00506-9     Document Type: Conference Paper

References (32)

1. Ignarro LJ. Nitric oxide: biology and pathobiology. San Diego: Academic Press; 2000.
2. Xie Q.W., Cho H.J., Calaycay J., Mumford R.A., Swiderek K.M., Lee T.D., Ding A., Troso T., Nathan C. Cloning and characterization of inducible nitric oxide synthase from mouse macrophages. Science. 256:1992;225-228.
3. Balligand J.L., Ungureanu-Longrois D., Simmons W.W., Kobzik L., Lowenstein C.J., Lamas S., Kelly R.A., Smith T.W., Michel T. Induction of NO synthase in rat cardiac microvascular endothelial cells by IL-1β and INF-γ Am. J. Physiol. 268:1995;H1293-H1303.
4. 2+-independent nitric oxide synthase in the myocardium. Br. J. Pharmacol. 105:1992;575-580.
5. Buttery L.D., Evans T.J., Springall D.R., Carpenter A., Cohen J., Polak J.M. Immunochemical localization of inducible nitric oxide synthase in endotoxin-treated rats. Lab. Invest. 71:1994;755-764.
6. McDonough K.H., Smith T., Patel K., Quinn M. Myocardial dysfunction in the septic rat heart: role of nitric oxide. Shock. 10:1998;371-376.
7. Feng Q., Lu X., Jones D.L., Shen J., Arnold J.M. Increased inducible nitric oxide synthase expression contributes to myocardial dysfunction and higher mortality after myocardial infarction in mice. Circulation. 104:2001;700-704.
8. Haywood G.A., Tsao P.S., von der Leyen H.E., Mann M.J., Keeling P.J., Trindade P.T., Lewis N.P., Byrne C.D., Rickenbacher P.R., Bishopric N.H., McKenna W.J., Fowler M.B. Expression of inducible nitric oxide synthase in human heart failure. Circulation. 93:1996;1087-1094.
9. Sumeray M.S., Rees D.D., Yellon D.M. Infarct size and nitric oxide synthase in murine myocardium. J. Mol. Cell. Cardiol. 32:2000;35-42.
10. Guo Y., Jones W.K., Xuan Y.T., Tang X.L., Bao W., Wu W.J., Han H., Laubach V.E., Ping P., Yang Z., Qiu Y., Bolli R. The late phase of ischemic preconditioning is abrogated by targeted disruption of the inducible NO synthase gene. Proc. Natl. Acad. Sci. U.S.A. 96:1999;11507-11512.
11. Ing D.J., Zang J., Dzau V.J., Webster K.A., Bishopric N. Modulation of cytokine-induced cardiac myocyte apoptosis by nitric oxide, Bak and Bcl-x. Circ. Res. 84:1999;21-33.
12. Arstall M., Sawyer D.B., Fukazawa R., Kelly R.A. Cytokine-mediated apoptosis in cardiac myocytes. The role of inducible nitric oxide synthase induction and peroxynitrite generation. Circ. Res. 85:1999;829-840.
13. Taimor G., Hofstaetter B., Piper H.M. Apoptosis induction by nitric oxide in adult cardiomyocytes via cGMP-signaling and its impairment after simulated ischemia. Cardiovasc. Res. 45:2000;588-594.
14. Xu L., Eu J.P., Meissner G., Stamler J.S. Activation of the cardiac calcium release channel (ryanodine receptor) by poly-S-nitrosylation. Science. 279:1998;234-237.
15. Gow A.J., Chen Q., Hess D.T., Day B.J., Ischiropoulos H., Stamler J.S. Basal and stimulated protein S-nitrosylation in multiple cell types and tissues. J. Biol. Chem. 277:2002;9637-9640.
16. Jourd'heuil D., Gray L., Grisham M.B. S-Nitrosothiol formation in blood of lipopolysaccharide-treated rats. Biochem. Biophys. Res. Commun. 273:2000;22-26.
17. Borutaite V., Morkuniene R., Brown G.C. Nitric oxide donors, nitrosothiols and mitochondrial respiration inhibitors induce caspase activation by different mechanisms. FEBS Lett. 467:2000;155-159.
18. Halestrap A.P., Kerr P.M., Javadov S., Woodfield K.Y. Elucidating the molecular mechanism of the permeability transition pore and its role in reperfusion injury of the heart. Biochem. Biophys. Acta. 1366:1998;79-94.
19. Crompton M. The mitochondrial permeability transition pore and its role in cell death. Biochem. J. 341:1999;233-249.
20. Borutaite V., Jekabsone A., Morkuniene R., Brown G C. Inhibition of mitochondrial permeability transition prevents mitochondrial dysfunction, cytochrome c release and apoptosis induced by heart ischemia. J. Mol. Cell. Cardiol. 35:2003;357-366.
21. Vande Velde C., Cizeau J., Dubik D., Alimonti J., Brown T., Israels S., Hakem R., Greenberg A.H. BNIP3 and genetic control of necrosis-like cell death through the mitochondrial permeability transition pore. Mol. Cell. Biol. 20:2000;5454-5468.
22. Bernardi P., Petronilli V., Di Lisa F., Forte M. A mitochondrial perspective on cell death. Trends Biochem. Sci. 26:2001;112-117.
23. Kroemer G., Reed J.C. Mitochondrial control of cell death. Nature. 6:2000;513-519.
24. Scholte H.R., Weijers P.J., Wit-Peeters E.M. Localisation of mitochondrial creatine kinase and its use for determination of sidedness of submitochondrial particles. Biochim. Biophys. Acta. 291:1973;764-773.
25. Rieske J.S. The quantitative determination of mitochondrial hemoproteins. Methods Enzymol. 10:1967;488-493.
26. Griffiths E.J., Halestrap A.P. Protection by cyclosporin A of ischemia/reperfusion-induced damage in isolated rat hearts. J. Mol. Cell. Cardiol. 25:1993;1461-1469.
27. + currents by the immunosuppresant FK-506 in rat ventricle. Am. J. Physiol. 275:1998;H2041-H2052.
28. Borutaite V., Budriunaite A., Morkuniene R., Brown G.C. Release of mitochondrial cytochrome c and activation of cytosolic caspases induced by myocardial ischaemia. Biochim. Biophys. Acta. 1537:2001;101-109.
29. Butzer U., Weidenbach H., Gansauge S., Gansauge F., Beger H.G., Nussler A.K. Increased oxidative stress in RAW 264.7 macrophage cell line is partially mediated via the S-nitrosothiol-induced inhibition of glutathione reductase. FEBS Lett. 445:1999;274-278.
30. Marley R., Patel R.P., Orie N., Ceaser E., Darley-Usmar V., Moore K. Formation of nanomolar concentrations of S-nitroso-albumin in human plasma by nitric oxide. Free Radic. Biol. Med. 31:2001;688-696.
31. Ottesen L.H., Harry D., Frost M., Davies S., Khan K., Halliwell B., Moore K. Increased formation of S-nitrosothiols and nitrotyrosine in cirrhotic rats during endotoxemia. Free Radic. Biol. Med. 31:2001;790-798.
32. Eu J.P., Liu L., Zeng M., Stamler J.S. An apoptotic model for nitrosative stress. Biochemistry. 39:2000;1040-1047.