The α2-adrenergic agonist guanfacine reduces excitability of human motor cortex through disfacilitation and increase of inhibition

Clinical Neurophysiology

Volumn 114, Issue 10, 2003, Pages 1834-1840

  Korchounov, Alexei ^a   Ilić, Tihomir V ^a   Ziemann, Ulf ^a  

^a GOETHE UNIVERSITY   (Germany)

Author keywords

Alpha2 adrenergic receptor agonist; Excitability; Guanfacine; Human motor cortex; Transcranial magnetic stimulation

Indexed keywords

ALPHA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; ESTULIC WANDER; GUANFACINE; ALPHA ADRENERGIC RECEPTOR STIMULATING AGENT;

ADULT; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG TOLERABILITY; HUMAN; HUMAN EXPERIMENT; MOTOR CORTEX; NEUROMUSCULAR BLOCKING; NEUROMUSCULAR FUNCTION; NEUROPHYSIOLOGY; NORMAL HUMAN; PRIORITY JOURNAL; SIDE EFFECT; THUMB; TRANSCRANIAL MAGNETIC STIMULATION; ANALYSIS OF VARIANCE; COMPARATIVE STUDY; ELECTROMAGNETIC FIELD; ELECTROMYOGRAPHY; ELECTROSTIMULATION; EVOKED MUSCLE RESPONSE; MAGNETISM; MOTOR ACTIVITY; NERVE CELL INHIBITION; PERCEPTIVE THRESHOLD; PHYSIOLOGY; RADIATION RESPONSE; SKELETAL MUSCLE; SPINAL CORD; TIME;

ADRENERGIC ALPHA-AGONISTS; ADULT; ANALYSIS OF VARIANCE; DOSE-RESPONSE RELATIONSHIP, RADIATION; ELECTRIC STIMULATION; ELECTROMAGNETIC FIELDS; ELECTROMYOGRAPHY; EVOKED POTENTIALS, MOTOR; GUANFACINE; HUMANS; MAGNETICS; MOTOR ACTIVITY; MOTOR CORTEX; MUSCLE, SKELETAL; NEURAL INHIBITION; SENSORY THRESHOLDS; SPINAL CORD; TIME FACTORS;

EID: 0642372560     PISSN: 13882457     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1388-2457(03)00192-5     Document Type: Article

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