Development of a High-Throughput Scintillation Proximity Assay for the Identification of C-Domain Translational Initiation Factor 2 Inhibitors

Journal of Biomolecular Screening

Volumn 7, Issue 6, 2002, Pages 541-546

  Fratte, Sonia Delle ^a,b   Piubelli, Chiara ^a   Domenici, Enrico ^a  

^a GSK   (Italy)

^b UNIVERSITY OF VERONA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

DIMETHYL SULFOXIDE; FMET TRNA(FMET); FMET-TRNA(FMET); INITIATION FACTOR 2; METHIONINE TRANSFER RNA; STREPTAVIDIN;

ARTICLE; BINDING COMPETITION; BIOASSAY; CHEMISTRY; COMBINATORIAL CHEMISTRY; DRUG ANTAGONISM; DRUG SCREENING; IC 50; METABOLISM; METHODOLOGY; PROTEIN TERTIARY STRUCTURE; RANDOMIZATION; REPRODUCIBILITY; SCINTILLATION COUNTING;

BINDING, COMPETITIVE; BIOLOGICAL ASSAY; COMBINATORIAL CHEMISTRY TECHNIQUES; DIMETHYL SULFOXIDE; DRUG EVALUATION, PRECLINICAL; INHIBITORY CONCENTRATION 50; PROKARYOTIC INITIATION FACTOR-2; PROTEIN STRUCTURE, TERTIARY; RANDOM ALLOCATION; REPRODUCIBILITY OF RESULTS; RNA, TRANSFER, MET; SCINTILLATION COUNTING; STREPTAVIDIN;

EID: 0642347836     PISSN: 10870571     EISSN: None     Source Type: Journal    
DOI: 10.1177/1087057102238628     Document Type: Article

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