Genomic structure and chromosomal localization of the human interleukin 15 gene (IL-15)

Cytokine

Volumn 8, Issue 9, 1996, Pages 667-674

  Krause, Hans ^b   Jandrig, Burkhard ^a   Wernicke, Catrin ^b   Bulfone Paus, Silvia ^b   Pohl, Thomas ^b   Diamantstein, Tibor ^b  

^a MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

^b CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

Chromosomal assignment; Fluorescence in situ hybridization; Gene structure; Interleukin 15; Somatic cell hybrids

Indexed keywords

CYTOKINE; INTERLEUKIN 15;

ARTICLE; CHROMOSOMAL LOCALIZATION; CHROMOSOME 4; CHROMOSOME 4Q; EXON; FLUORESCENCE IN SITU HYBRIDIZATION; GENE LOCATION; GENE MAPPING; GENE SEQUENCE; GENE STRUCTURE; HUMAN; HUMAN CELL; HYBRID CELL; INTRON; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SEQUENCE HOMOLOGY; SOUTHERN BLOTTING;

MURINAE; RODENTIA;

EID: 0642343623     PISSN: 10434666     EISSN: None     Source Type: Journal    
DOI: 10.1006/cyto.1996.0089     Document Type: Article

References (23)

1. 1. Gillis S, Smith KA (1977) Long term culture of tumour-specific cytotoxic T cells. Nature 268:154-156.
2. 2. Grabstein KH, Eisenman J, Shanebeck K, Raunch C, Srinivasan S, Fung V, Beers C, Richardson J, Schoenborn MA, Ahdieh M, Johnson L, Alderson MR, Watson JD, Anderson DM, Giri JG (1994) Cloning of a T cell growth factor that interacts with the beta chain of the interleukin 2 receptor. Science 264:965-968.
3. 3. Carson WE, Giri JG, Lindemann MJ, Linett ML, Ahdieh M, Paxton R, Anderson D, Eisenmann J, Grabstein K, Caligiuri MA (1994) Interleukin (IL) 15 is a novel cytokine that activates human natural killer cells via components of the IL-2 receptor. J Exp Med 180:1395-1403.
4. 4. Armitage RJ, Macduff BM, Eisenman J, Paxton R, Grabstein KH (1995) IL-15 has stimulatory activity for the induction of B cell proliferation and differentiation. J Immunol 154:483-490.
5. 5. Quinn LS, Haugk KL, Grabstein KH (1995) Interleukin-15: a novel anabolic cytokine for the skeletal muscle. Endocrinol 136:3669-3672.
6. 6. Wilkinson PC, Liew FY (1995) Chemoattraction of human blood T lymphocytes by interleukin-15. J Exp Med 181:1255-1259.
7. 7. Giri JG, Ahdieh M, Eisenman J, Shanebeck K, Grabstein K, Kumaki S, Namen A, Park LS, Cosman D, Anderson D (1994) Utilization of the beta and gamma chains of the IL-2 receptor by the novel cytokine IL-15. EMBO J 13:2822-2830.
8. 8. Lin JX, Migone TS, Tsang M, Friedmann M, Weatherbee JA, Zhou L, Yamauchi A, Bloom ET, Mietz J, John S, Leonard WJ (1995) The role of shared receptor motifs and common Stat proteins in the generation of cytokine pleitropy and redundancy by IL-2, IL-4, IL-7, IL-13, and IL-15. Immunity 2:331-339.
9. 9. Bazan JF (1990) Haemopoietic receptors and helical cytokines. Immunol Today 11:350-354.
10. 10. Cosman D (1993) The haematopoietin receptor superfamily. Cytokine 5:95-106.
11. 11. Fujita T, Takaoka C, Matsui H, Taniguchi T (1983) Structure of the human interleukin 2 gene. Proc Natl A cad Sci USA 80:7437-7441.
12. 12. Giri JG, Kumaki S, Ahdieh M, Friend DJ, Loomis A, Shanebeck K, DuBose R, Cosman D, Park LS, Anderson DM (1995) Identification and cloning of a novel IL-15 binding protein that is structurally related to the α chain of the IL-2 receptor. EMBO J 14:3654-3663.
13. 13. Giri JG, Anderson DM, Kumaki S, Park LS, Grabstein KH, Cosman D (1995) IL-15, a novel T cell growth factor that shares activities and receptor components with IL-2. J Leukoc Biol 57:763-766.
14. 14. Anderson DM, Johnson L, Glaccum MB, Copeland NG, Gilbert DJ, Jenkins NA, Valentine V, Kirstein MN, Shapiro DN, Morris SW, Grabstein K, Cosman D (1995) Chromosomal assignment and genomic structure of IL-15. Genomics 25:701-706.
15. 15. Lupton SD, Gimpel S, Jerzy R, Brunton LL, Hjerrild KA, Cosman D, Goodwin RG (1990) Characterization of the human and murine IL-7 genes. J Immunol 144:3592-3601.
16. 16. Padgett RA, Grabowski PJ, Konarska MM, Seiler S, Sharp PA (1986) Splicing of messenger RNA precursors. Annu Rev Biochem 55:1119-1150.
17. 17. Murray JC, van Ommen GJB (1991) Report of the committee on the genetic constitution of chromosome 4. Cytogenet Cell Genet 58:231-260.
18. 18. Altherr MR, Bengtsson U, Markovich RP, Winokur ST (1995) Efforts toward understanding the molecular basis of facioscapulohumeral muscular dystrophy. Muscle Nerve [Suppl 2]: S32-S38.
19. 19. Wijmenga C, Dauwerse HG, Padberg GW, Meyer N, Murray JC, Mills K, van Ommen GB, Hofker MH, Frants RR (1995) Fish mapping of 250 cosmid and 26 YAC clones to chromosome 4 with special emphasis on the FSHD region at 4q35. Muscle Nerve [Suppl 2]:S14-S18.
20. 20. Rychlik W, Rhoads RE (1989) A computer program for choosing optimal oligonucleotides for filter hybridization, sequencing and in vitro amplification of DNA. Nucleic Acids Res 17: 8543-8551.
21. 21. Sambrook J, Fritsch EF, Maniatis T (1989) Molecular Cloning - A Laboratory Manual. 2nd edn. Cold Spring Harbor, Cold Spring Harbor Press.
22. 22. Lichter P, Cremer T, Borden J, Manuelidis L, Ward DC (1988) Delineation of individual human chromosomes in metaphase and interphase cells by in situ suppression hybridization using recombinant DNA libraries. Hum Genet 80:224-234.
23. 23. Pinkel D, Straume T, Gray JW (1986) Cytogenetic analysis using quantitive, high-sensitivity, fluorescence hybridization. Proc Natl Acad Sci USA 83:2934-2938.