Six new andrographolide metabolites in rats

Chemical and Pharmaceutical Bulletin

Volumn 51, Issue 5, 2003, Pages 586-589

  He, Xiangjiu ^a   Li, Jiankuan ^a   Gao, Hao ^a   Qiu, Feng ^a   Cui, Xiangmin ^b   Yao, Xinsheng ^a  

^a SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

^b Pan Pacific Pharmaceutical Company Ltd   (United States)

Author keywords

14 deoxy 12(R) sulfo andrographolide 3 sulfate; 14 deoxy 12(S) sulfo andrographolide 3 sulfate; 14 sulfo isoandrographolide 3 sulfate; Andrographolide; Metabolite in rats; Sulfate ester

Indexed keywords

14 DEOXY 11,12 DIDEHYDROANDROGRAPHOLIDE 3 SULFATE; 14 DEOXY SULFOANDROGRAPHOLIDE 3 SULFATE; 14 DEOXYANDROGRAPHOLIDE; 14 SULFOISOANDROGRAPHOLIDE 3 SULFATE; ANDROGRAPHOLIDE; ISOANDROGRAPHOLIDE; SULFATE; UNCLASSIFIED DRUG; CARBON; DITERPENE; NONSTEROID ANTIINFLAMMATORY AGENT; PROTON;

ARTICLE; DRUG ISOLATION; DRUG STRUCTURE; FECES; MALE; METABOLITE; NONHUMAN; RAT; SMALL INTESTINE; SPECTROSCOPY; URINE; ANIMAL; CHEMISTRY; ELECTROSPRAY MASS SPECTROMETRY; INFRARED SPECTROPHOTOMETRY; METABOLISM; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; ULTRAVIOLET SPECTROPHOTOMETRY; WISTAR RAT;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CARBON; DITERPENES; FECES; MAGNETIC RESONANCE SPECTROSCOPY; MALE; PROTONS; RATS; RATS, WISTAR; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SPECTROPHOTOMETRY, INFRARED; SPECTROPHOTOMETRY, ULTRAVIOLET;

EID: 0642340617     PISSN: 00092363     EISSN: 13475223     Source Type: Journal    
DOI: 10.1248/cpb.51.586     Document Type: Article

References (11)

1. Shen Y. C., Chen C. F., Chiou W. F., Br. J. Pharmacol., 135, 399-406 (2002).
2. Sinha J., Mukhopadhyay S., Das N., Basu M. K., Drug Deliv., 7, 209-213 (2000).
3. Calabrese C., Berman S. H., Babish J. G., Ma X., Shinto L., Dorr M., Wells K., Wenner C. A., Standish L. J., Phytother. Res., 14, 333-338 (2000).
4. Amroyan E., Gabrielian E., Panossian A., Wikman G., Wagner H., Phytomedicine, 6, 27-31 (1999).
5. Zhang C. Y., Tan B. K., J. Ethnopharmacol, 56, 97-101 (1997).
6. Visen P. K., Shukla B., Patnaik G. K., Dhawan B. N., J. Ethnopharmacol, 40, 131-136 (1993).
7. Handa S. S., Sharma A., Indian J. Med. Res., 92, 284-292 (1990).
8. Panossian A., Hovhannisyan A., Mamikonyan G., Abrahamian H., Hambardzumyan E., Gabrielian E., Goukasova G., Wikman G., Wagner H., Phytomedicine, 7, 351-364 (2000).
9. Zhu S. P., Kang B. A., Zhongguo Yao Li Xue Bao, 2, 266-269 (1981).
10. Zhang S. J., Masayoshi A., Chin. J. Med. Chem., 7, 270-273 (1997).
11. Takakuni M., Masanori K., Satoko S., Umehara K., Ueno A., Nishi K., Chem. Pharm. Bull., 42, 1216-1225 (1994).