Targeting aurora2 kinase in oncogenesis: A structural bioinformatics approach to target validation and rational drug design

Molecular Cancer Therapeutics

Volumn 2, Issue 3, 2003, Pages 283-294

  Vankayalapati, Hariprasad ^a,b   Bearss, David J ^a   Saldanha, José W ^a,c   Mũnoz, Rubén M ^a   Rojanala, Sangeeta ^a   Von Hoff, Daniel D ^a   Mahadevan, Daruka ^a  

^a UNIVERSITY OF ARIZONA   (United States)

^b UNIVERSITY OF ARIZONA   (United States)

^c NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AIR 2 PROTEIN, C ELEGANS; AIR-2 PROTEIN, C ELEGANS; ANTINEOPLASTIC AGENT; AURKA PROTEIN, HUMAN; AURKA PROTEIN, MOUSE; AURKB PROTEIN, HUMAN; AURKB PROTEIN, MOUSE; CAENORHABDITIS ELEGANS PROTEIN; CALMODULIN BINDING PROTEIN; CYCLIC AMP DEPENDENT PROTEIN KINASE; MUSCLE PROTEIN; PROTEIN SERINE THREONINE KINASE; STAUROSPORINE; UNC 22 PROTEIN, C ELEGANS; UNC-22 PROTEIN, C ELEGANS;

AMINO ACID SEQUENCE; ANIMAL; ARTICLE; BIOLOGY; CAENORHABDITIS ELEGANS; CATTLE; CHEMICAL STRUCTURE; CHEMISTRY; COMPARATIVE STUDY; DRUG ANTAGONISM; DRUG DESIGN; ENZYMOLOGY; HUMAN; METABOLISM; MOLECULAR GENETICS; MOUSE; PANCREAS TUMOR; PROTEIN CONFORMATION; SEQUENCE HOMOLOGY; STRUCTURE ACTIVITY RELATION;

AMINO ACID SEQUENCE; ANIMALS; ANTINEOPLASTIC AGENTS; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; CALMODULIN-BINDING PROTEINS; CATTLE; COMPUTATIONAL BIOLOGY; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DRUG DESIGN; HUMANS; MICE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MOLECULAR STRUCTURE; MUSCLE PROTEINS; PANCREATIC NEOPLASMS; PROTEIN CONFORMATION; PROTEIN-SERINE-THREONINE KINASES; SEQUENCE HOMOLOGY, AMINO ACID; STAUROSPORINE; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0642303123     PISSN: 15357163     EISSN: 15388514     Source Type: Journal    
DOI: None     Document Type: Article

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