Does lindane (gamma-hexachlorocyclohexane) increase the rapid delayed rectifier outward K+ current (IKr) in frog atrial myocytes?

BMC Pharmacology

Volumn 2, Issue , 2002, Pages

  Sauviat, Martin Pierre ^a   Colas, Anthony ^a   Pages, Nicole ^b  

^a INSERM   (France)

^b UNIVERSITÉ DE STRASBOURG   (France)

Author keywords

[No Author keywords available]

Indexed keywords

HEXACHLOROCYCLOHEXANE; LINDANE; POTASSIUM ION; QUINIDINE; RINGER SOLUTION; 1 [2 (6 METHYL 2 PYRIDYL)ETHYL] 4 (4 METHYLSULFONYLAMINOBENZOYL)PIPERIDINE; ANTIARRHYTHMIC AGENT; DELAYED RECTIFIER POTASSIUM CHANNEL; PIPERIDINE DERIVATIVE; POTASSIUM CHANNEL; POTASSIUM CHANNEL BLOCKING AGENT; PYRIDINE DERIVATIVE; VOLTAGE GATED POTASSIUM CHANNEL;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; FROG; HEART ATRIUM; HEART DISEASE; HEART MUSCLE CELL; HEART REPOLARIZATION; INTRACELLULAR RECORDING; MEMBRANE POTENTIAL; MICROELECTRODE; MUSCLE ACTION POTENTIAL; NONHUMAN; POTASSIUM CURRENT; SENSITIVITY ANALYSIS; VOLTAGE CLAMP; ACTION POTENTIAL; ANIMAL; CYTOLOGY; DRUG EFFECT; ELECTROPHYSIOLOGY; HEART MUSCLE; METABOLISM; PHYSIOLOGY;

ACTION POTENTIALS; ANIMALS; ANTI-ARRHYTHMIA AGENTS; DELAYED RECTIFIER POTASSIUM CHANNELS; ELECTROPHYSIOLOGY; HEART ATRIA; LINDANE; MYOCARDIUM; MYOCYTES, CARDIAC; PIPERIDINES; POTASSIUM CHANNEL BLOCKERS; POTASSIUM CHANNELS; POTASSIUM CHANNELS, VOLTAGE-GATED; PYRIDINES; QUINIDINE; RANIDAE;

EID: 0642278833     PISSN: 14712210     EISSN: None     Source Type: Journal    
DOI: 10.1186/1471-2210-2-15     Document Type: Article

References (34)

1. Wauchope RD, Buttler TM, Hornsby AG, Augustijn-Beckers PW, Burt JP: The SCS/ARS/CES pesticide properties database for environmental decision making. Rev. Environ. Contam Toxicol 1992, 123:1-155
2. Srinivasan K, Radhakrishnamurty R: Studies on the distribution of beta- and gamma-isomers of hexachlorocyclohexane in rat tissues. J Environ Sci Health B. 1983, 18:401-418
3. Narahashi T: Neuronal ion channels as the target sites of insecticides. Pharmacol & Toxicol 1996, 78:1-14
4. Pomes A, Rodriguez-Farre E, Sunol C: Disruption of GABA-dependent chloride flux by cyclodienes and hexachlorocyclohexanes in primary cultures of cortical neurons. J Pharmacol Exp Ther 1994, 271:1616-1623
5. Parries GS, Hokin-Nevaverson M: Inhibition of phosphatidylinositol synthase and other membrane-associated enzymes by stereoisomers of hexachlorocyclohexane. J Biol Chem 1985, 260:2687-2693
6. 2+ influx, gamma-hexachlorocyclohexane. Biochem Biophys Res Commun 1994, 199:699-705
7. Criswell KA, Stuenkel EL, Loch-Caruso R: Lindane increases intracellular calcium in rat myometrial smooth muscle cells through modulation of inositol 1, 4, 5-triphosphate-sensitive stores. J Pharmacol Exp Ther 1994, 270:1015-1024
8. 2+ influx. Biochem J 1997, 321:691-698
9. Buck ED, Lachnit WG: In Pessah: Mechanisms of delta-hexachloracyclohexane toxicity: I. Relationship between altered ventricular myocyte contractility and ryanodine receptor function. J Pharmacol Exp Ther 1999, 289:477-485
10. 2+ release and capacitative Ca2+ entry in Madin-Darby canine kidney cells. Pharmacol Toxicol 2000, 87:149-155
11. + currents in GH(3) lactotrophs. Mol Pharmacol 2000, 57:865-874
12. + channel by external divalent cations in guinea-pig cardiac myocytes. Pflügers Arch 1993, 422:427-435
13. Coraboeuf E, Carmeliet E: Existence of two transient outward currents in sheep cardiac Purkinje fibrers. Pflügers Arch 1982, 392:352-359
14. Snyders DJ, Knoth KM, Roberts SL, Tamkun HH: Time-, voltageand state-dependent block by quinidine of a cloned human cardiac potassium channel. Mol Pharmacol 1992, 41:322-330
15. Snyders DJ: Functional and pharmacological diversity of mammalian potassium channels. A molecular approach: In "Potassium channels in normal and pathological conditions". (Edited by: J. Verreecke, PP. van Bogaert, F. Verdonck) L University Press, Leuven 1995, 81-101
16. Snyders DJ: Structure and function of cardiac potassium channels. Cardiovasc Res 1999, 42:377-390
17. Tseng GN: I(Kr): the hERG channel. J Mol Cell Cardiol 2001, 33:838-849
18. + current. Differential sensitivity to block by class III antiarrhythmic agents. J Gen Physiol 1990, 96:195-215
19. + current in cardiac myocytes by dofetilide. J Pharmacol Exp Ther 1992, 262:809-817
20. Kr, in rabbit ventricular myocytes. Biophys J 1998, 74:1278-1285
21. Wang Q, Shen J, Li Z, Timothy K, Vincent GM, Priori SG, Schwartz PJ, Keating MT: Cardiac sodium channel mutations in patients with long QT syndrome, an inherited cardiac arrhythmia. Hum Mol Genet 1995, 4:1603-1607
22. Wang Q, Curran ME, Splawski I, Burn TC, Millholland JM, Van Raay TJ, Shen J, Timothy KW, Vincent GM, de Jager T, Schwartz PJ, Toubin JA, Moss AJ, Atkinson DL, Landes GM, Connors TD, Keating MT: Positional cloning of a novel potassium channel gene: KVLQT1 mutations cause cardiac arrhythmias. Nat Genet 1996, 12:17-23
23. Barhanin J, Lesage F, Guillemare E, Fink M, Lazdunski M, Romey G: K(V)LQT1 and lsK (minK) proteins associate to form the I(Ks) cardiac potassium current. Nature 1996, 384:78-80
24. Sanguinetti MC, Jiang C, Curran ME, Keating MT: A mechanistic link between an inherited and an acquired cardiac arrhythmia: HERG encodes the IKr potassium channel. Cell 1995, 81:299-307
25. Sanguinetti MC, Curran ME, Zou A, Shen J, Spector PS, Atkinson DL, Keating MT: Coassembly of K(V)LQT1 and minK (IsK) proteins to form cardiac I(Ks) potassium channel. Nature 1996, 384:80-83
26. Witchel HJ, Hancox JC: Familial and acquired long QT syndrome and the cardiac rapid delayed rectifier potassium current. Clin Exp Pharmacol Physiol 2000, 27:753-766
27. Kiehn J, Karle C, Thomas D, Yao X, Brachmann J, Kübler W: HERG potassium channel activation is shifted by phorbol esters via protein kinase A-dependent pathways. J Biol Chem 1998, 273:25285-25291
28. + channel gating by activation of a G protein-coupled receptor and protein kinase C. J Physiol 1998, 511:333-346
29. Heath BM, Terrar DA: Proteine kinase C enhances the rapidly activating delayed rectifier potassium current, IKr, through a reduction in C-type inactivation in guinea-pig ventricular myocytes. J Physiol 2000, 522:391-402
30. Bagchi D, Bagchi L, Stohs SJ: Comparative in vitro and in vivo protein kinase C activation by selected pesticides and transition metal salts. Toxicol Let 1997, 91:31-37
31. Bian J, Cui J, McDonald TV: HERG K(+) channel activity is regulated by changes in phosphatidyl inositol 4,5-bisphosphate. Circ Res 2001, 89:1168-1176
32. Agrawaal D, Subramoiam A, Afaq F: Influence of hexachlorocyclohexane on phosphoinisitides in rat erythrocyte membranes and brain. Toxicology 1995, 95:135-140
33. Sauviat M-P, Meunier FA, Kreger A, Molgó J: Effects of trachynilysin, a protein isolated from stonefish (Synanceia trachynis) venom, on frog atrial heart muscle. Toxicon 2000, 38:945-959
34. Sauviat M-P, Benoit AG, Debitus C, Pouny I, Laurent D: Alterations of transmembrane currents in frog atrial heart muscle induced by photoexcited gymnochrome a purified from the crinoid, Gymnochrinus richerii. Photochem Photobiol 2001, 74:115-119