Degenerative axonal changes in the hippocampus and amygdala in Parkinson's disease

Folia Neuropathologica

Volumn 41, Issue 4, 2003, Pages 197-207

  Bertrand, Ewa ^a   Lechowicz, Waldemar ^a   Lewandowska, Eliza ^a   Szpak, Grazyna ^a   Dymecki, Jerzy ^a   Kosno Kruszewska, Elzbieta ^a   Wierzba Bobrowicz, Teresa ^a  

^a INSTITUTE OF PSYCHIATRY AND NEUROLOGY   (Poland)

Author keywords

Amygdala; Axonal pathology; Hippocampus; Immunohistochemistry; Parkinson's disease

Indexed keywords

ALPHA SYNUCLEIN; BETA SYNUCLEIN; PROTEIN; SYNAPTIC PROTEIN; SYNAPTOBREVIN; SYNAPTOPHYSIN; UNCLASSIFIED DRUG;

ADULT; AGED; AMYGDALOID NUCLEUS; ARTICLE; AUTOPSY; BEHAVIOR; BRAIN ATROPHY; BRAIN FUNCTION; CELL ULTRASTRUCTURE; CLINICAL ARTICLE; COGNITION; CONTROLLED STUDY; DENTATE GYRUS; ELECTRON MICROSCOPY; EMOTION; ENTORHINAL CORTEX; FEMALE; HIPPOCAMPUS; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; LEWY BODY; LIMBIC SYSTEM; MALE; MICROSCOPY; NERVE FIBER; NERVE FIBER DEGENERATION; NEURITE; PARKINSON DISEASE; PERIKARYON; PRESYNAPTIC NERVE; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; STRUCTURE ANALYSIS; SYMPTOMATOLOGY; SYNAPTIC TRANSMISSION;

EID: 0442326209     PISSN: 16414640     EISSN: 1509572X     Source Type: Journal    
DOI: None     Document Type: Article

References (31)

1. Braak H, Braak E (1991) Neuropathological stenting of Alzheimer-related changes. Acta Neuropathol (Berl), 82: 239-259.
2. Braak H, Braak E, Yilmazer D, de Vos RAI, Jansen ENH, Bohl J (1996) Pattern of brain destruction in Parkinson's and Alzheimer's diseases. J Neural Transm, 103: 455-490.
3. Braak H, Braak E, Yilmazer D, deVos RAI, Jansen ENH, Bohl J, Jelinger K (1994) Amygdala pathology in Parkinson's disease. Acta Neuropathol, 88: 493-500.
4. Chuchard A, Lees AJ (1997) The relationship between dementia and direct involvement of the hippocampus and amygdala in Parkinson's disease. Neurology, 49: 1570-1576.
5. Dayas CV, Day TA (2002) Opposing roles for medial and central amygdala in the initiation of noradrenergic cell responses to a psychological stressor. Eur J Neurosci, 15: 1712-1718.
6. De Olmos JS (1990) Amygdala. In: The Human Nervous System, ed. Praxinos G. Academic Press, New York, 583-710.
7. Dickson DW, Ruan D, Crystal H, Mark MH, Davies P, Kress Y, Yen S-H (1991) Hippocampal degeneration differentiates diffuse Lewy body disease (DLBD) from Alzheimer's disease: Light and electron microscopic immunocytochemistry of CA2-3 neurities specific to DLBD. Neurology, 41: 1402-1409.
8. Duda JE, Lee V M-Y, Trojanowski JQ (2000) Mini-Review. Neuropathology of synuclein aggregates: New insights into mechanisms of neurodegenerative diseases. J Neurosci Res, 61: 121-127.
9. Gai WP, Yuan HX, Li XQ, Power JTH, Blumbergs PC, Jensen PH (2000) In situ and in vitro study of colocalization and segregation of α-synucleic, ubiquitin, and lipids in LBs. Exp Neurol, 166: 324-333.
10. Galvin JE, Uryu K, Lee VM, Trojanowski JQ (1999) Axon pathology in Parkinson's disease and Lewy body dementia hippocampus contains alfa-, beta-, and gamma synuclein. Proc Natl Acad Sci, 96: 13450-13455.
11. Gearing M, Mirra SS, Hedreen JC, Sumi SM, Hansen LA, Heyman A (1995) The consortium to establish a registry for Alzheimer's disease (CERAD). Part X. Neuropathology confirmation of clinical diagnosis of Alzheimer's disease. Neurology, 45: 461-466.
12. Han J-S, McMahan RW, Holland P, Gallagher M (1997) The role of an amygdalo-nigrostriatal pathway in associative learning. J Neurosci, 17: 3913-3919.
13. Harding AJ, Halliday GM (1998) Simplified neuropathological diagnosis of dementia with Lewy bodies. Neuropathol Appl Neurobiol, 24: 195-201.
14. Harding AJ, Halliday GM (2001) Cortical Lewy body pathology in diagnosis of dementia. Acta Neuropathol (Berl), 102: 355-363.
15. Harding AJ, Kil JJ, Halliday GM (2000) Practical measures to simplify the Braak tangle staging method for routine pathological screening. Acta Neuropathol (Berl), 99: 199-208.
16. Heyman A, Fillenbaum GG, Gearing M, Mirra SS, Welsh-Bohmer KA, Peterson B, Piepper C (1999) Comparison of Lewy body variant of AD with pure AD. Consortium to establish a registry for Alzheimer's disease, Part XIX, Neurology, 52: 1839-1844.
17. Holstege G (1996) The somatic motor system. In: Progress in Brain Res, 107: 9-26.
18. Hughes AJ, Daniel SE, Blankson S, Lees AJ (2001) Improved accuracy of clinical diagnosis of Lewy body Parkinson's disease. Neurology, 57: 1497-1499.
19. Hurtig HI, Trojanowski JQ, Galwin J, Ewbank D, Schmidt MNL, Lee VM-Y, Clark CM, Glosser G, Stern MB, Gollomp SM, Arnold SE (2000) Alpha-synuclein cortical Lewy bodies correlate with dementia in Parkinson's disease. Neurology, 54: 1916-1921.
20. Lowe J (1998) Establishing a pathological diagnosis in degenerative dementias. Brain Pathol, 8: 403-406.
21. Martin J (1996) The limbic system. In: Neuroanatomy: Text and Atlas, eds. Appelton and Lange, Stanford London, 447-495.
22. Matilla PM, Rinne JO, Helenius H, Röyttä M (1999) Neuritic degeneration in the hippocampus and amygdala in Parkinson's disease in relation to Alzheimer's pathology. Acta Neuropathol, 98: 157-164.
23. Matilla PM, Rinne JO, Helenius H, Dickson DW, Röyttä M (2000) Alpha-synuclein immunoreactive cortical Lewy bodies are associated with cognitive impairment in Parkinson's disease. Acta Neuropathol (Berl), 100: 285-290.
24. McKeith IG, Galasko D, Kosaka K, Perry EK, Dickson DW, Hansen LA et al. (1996) Consensus guidelines for the clinical and pathologic diagnosis of dementia with Lewy bodies (DLB). Report of the consortium on DLB International Workshop. Neurology, 47: 111-112.
25. Mirra SS, Heyman A, McKeel D, Sumi SM, Crain BJ, Brownlee LM, Vogelm FS, Hughes JP, Van Belle G, Berg L and participating CERAD neuropathlogists (1991) The consortium to establish a registry for Alzheimer disease (CERAD). Part II. Standardization of the neuropathologic assessment of Alzheimer's disease. Neurology, 41: 479-486.
26. Nieoullon A (2002) Cognitive deficits in Parkinson's disease. In: Progress in Neurobiol, 67: 55-57.
27. Nieuwenhuys R (1996) The greater limb system, the emotional motor system and the brain. In: Progress in Brain Res, eds.: Holstege G, Bandler R, Saper CB, Elsevier Science B.V., 107: 551-580.
28. Poewe N and Wenning G (2002) The differential diagnosis of Parkinson's disease. Eur J Neurol, 9 (Suppl. 3): 23-30.
29. Price JL (1990) Olfactory system. In: The Human Nervous System, ed. Praxinos G, Academic Press, New York, 979-988.
30. Sandmann-Keil D, Braak H, Okochi M, Haass CH, Braak E (1999) Alpha-synuclein immunoreactive Lewy bodies and Lewy neurites in Parkinson's disease are detectable by an advanced silver-staining technique. Acta Neuropathol, 98: 461-464.
31. Simonian NA, Rebeck GW, Hyman BT (1994) Functional integrity of neural systems related to memory in Alzheimer's disease. In: Progress in Brain Res, ed.: Bloom F, Elsevier Science BV, 100: 245-254.