Effects of HR780, a Novel 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Inhibitor, in Watanabe Heritable Hyperlipidemic Rabbits and Cholesterol-Fed Rabbits

Pharmacology

Volumn 70, Issue 3, 2004, Pages 123-129

  Wajima, Teruaki ^a   Makita, Shigeki ^a   Oshima, Kenichi ^a  

^a Aventis Pharma Ltd   (Japan)

Author keywords

3 Hydroxy 3 methylglutaryl coenzyme A reductase inhibitor; Gallbladder, lipid contents; Hypercholesterolemia; Lipid; Liver cholesterol; Phospholipid; Simvastatin; Statin

Indexed keywords

6 [2 [4 (4 FLUOROPHENYL) 2 ISOPROPYL 6 PHENYL 3 PYRIDYL]VINYL] 3,4,5,6 TETRAHYDRO 4 HYDROXY 2H PYRAN 2 ONE; BILE ACID; CHOLESTEROL; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; PHOSPHOLIPID; SIMVASTATIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHOLESTEROL BLOOD LEVEL; CHOLESTEROL LIVER LEVEL; CONCENTRATION (PARAMETERS); CONCENTRATION RESPONSE; CONTROLLED STUDY; DIETARY INTAKE; DOSE RESPONSE; DRUG EFFECT; DRUG STRUCTURE; EVALUATION; FEEDING; GALLBLADDER; HERITABILITY; HYPERCHOLESTEROLEMIA; HYPERLIPIDEMIA; MALE; NONHUMAN; PRIORITY JOURNAL; RABBIT;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; BILE; CHOLESTEROL; CHOLESTEROL, DIETARY; DISEASE MODELS, ANIMAL; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; HYPERLIPIDEMIAS; JAPAN; LIPIDS; LIVER; MALE; PYRIDINES; RABBITS; SIMVASTATIN;

EID: 0442293413     PISSN: 00317012     EISSN: None     Source Type: Journal    
DOI: 10.1159/000074975     Document Type: Article

References (21)

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