Gas chromatography-electron ionization mass spectrometry and liquid chromatography-electrospray tandem mass spectrometry for determination of impurities in the anti-cancer drug isophosphoramide mustard

International Journal of Mass Spectrometry

Volumn 231, Issue 2-3, 2004, Pages 147-155

  Cole, Richard B ^a   Chou, Chau Wen ^a   Boué, Stephen M ^b   LeBlanc, Blaise W ^c   Rodgers, Andrew H ^c   Struck, Robert F ^d   Morgan, Lee Roy ^c  

^a UNIVERSITY OF NEW ORLEANS   (United States)

^b SOUTHERN REGIONAL RESEARCH CENTER   (United States)

^c DEKK TEC Incorporated   (United States)

^d SOUTHERN RESEARCH INSTITUTE   (United States)

Author keywords

IPM; Isophosphoramide mustard; LC ES MS MS; Mass spectrometry; Perchloric acid

Indexed keywords

ANTINEOPLASTIC AGENT; DIAMINE DERIVATIVE; ISOPHOSPHAMIDE MUSTARD; N (2 CHLOROETHYL) N' ETHYLPHOSPHORODIAMIDIC ACID; UNCLASSIFIED DRUG;

ANALYTIC METHOD; ARTICLE; CHEMICAL MODIFICATION; CHLORINATION; DEHYDROCHLORINATION; DRUG DETERMINATION; DRUG IMPURITY; DRUG SYNTHESIS; ELECTROSPRAY MASS SPECTROMETRY; GAS CHROMATOGRAPHY; HYDROGENATION; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY;

EID: 0442292302     PISSN: 13873806     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijms.2003.10.013     Document Type: Article

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