Replicons from positive strand RNA viruses for naked RNA immunization against influenza

International Congress Series

Volumn 1219, Issue C, 2001, Pages 923-929

  Vignuzzi, Marco ^a   Gerbaud, Sylvie ^a   van der Werf, Sylvie ^a   Escriou, Nicolas ^a  

^a INSTITUT PASTEUR   (France)

Author keywords

Cytotoxic T lymphocytes; Hemagglutinin; Humoral response; Nucleoprotein; Picornavirus; Recombinant; Semliki Forest virus; Vaccine vector

Indexed keywords

EID: 0442273110     PISSN: 05315131     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S0531-5131(01)00409-5     Document Type: Article

References (9)

1. Ulmer, J.B., Donnelly, J.J., Parker, S.E., Rhodes, G.H., Felgner, P.L., Dwarki, V.J., et al. Heterologous protection against influenza by injection of DNA encoding a viral protein. Science 259:5102 (1993), 1745–1749.
2. Donnelly, J.J., Ulmer, J.B., Liu, M.A., Immunization with DNA. J. Immunol. Methods 176:2 (1994), 145–152.
3. Donnelly, J.J., Friedman, A., Martinez, D., Montgomery, D.L., Shiver, J.W., Motzel, S.L., et al. Preclinical efficacy of a prototype DNA vaccine: enhanced protection against antigenic drift in influenza virus. Nat. Med. 1:6 (1995), 583–587.
4. Bender, B.S., Ulmer, J.B., DeWitt, C.M., Cottey, R., Taylor, S.F., Ward, A.M., et al. Immunogenicity and efficacy of DNA vaccines encoding influenza A proteins in aged mice. Vaccine 16:18 (1998), 1748–1755.
5. Marc, D., Drugeon, G., Haenni, A.L., Girard, M., van der Werf, S., Role of myristoylation of poliovirus capsid protein VP4 as determined by site-directed mutagenesis of its N-terminal sequence. EMBO J. 8:9 (1989), 2661–2668.
6. Lobert, P.E., Escriou, N., Ruelle, J., Michiels, T., A coding RNA sequence acts as a replication signal in cardioviruses. Proc. Natl. Acad. Sci. U. S. A. 96:20 (1999), 11560–11565.
7. Liljestrom, P., Garoff, H., A new generation of animal cell expression vectors based on the Semliki Forest virus replicon. Bio/Technology 9:12 (1991), 1356–1361.
8. Zhou, X., Berglund, P., Rhodes, G., Parker, S.E., Jondal, M., Liljeström, P., Self-replicating Semliki Forest virus RNA as recombinant vaccine. Vaccine 12 (1994), 1510–1514.
9. Dalemans, W., Delers, A., Delmelle, C., Denamur, F., Meykens, R., Thiriart, C., et al. Protection against homologous influenza challenge by genetic immunization with SFV-RNA encoding Flu-HA. Ann. N. Y. Acad. Sci. 772 (1995), 255–256.