Principal component analysis and neural networks for detection of amino acid biosignatures

Icarus

Volumn 166, Issue 2, 2003, Pages 403-409

  Dorn, Evan D ^a   McDonald, Gene D ^b   Storrie Lombardi, Michael C ^b   Nealson, Kenneth H ^b  

^a CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

^b CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

Amino acids; Exobiology; Life detection; Meteorites; Murchison; Neutral networks; Principal component analysis

Indexed keywords

EID: 0348234118     PISSN: 00191035     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.icarus.2003.08.011     Document Type: Article

References (23)

1. Bada, J.L., McDonald, G.D., 1996. Detecting amino acids on Mars. Anal. Chem. 68, A668.
2. Bada, J.L., Wang, X.S., Poinar, H.N., Paabo, S., Poinar, G.O., 1994. Amino-acid racemization in amber-entombed insects - implications for DNA preservation. Geochim. Cosmochim. Acta 58, 3231-3235.
3. Cowie, G.L., Hedges, J.I., Calvert, S.E., 1992. Sources and relative reactivities of amino acids, neutral sugars, and lignin in an intermittently anoxic marine environment. Geochim. Cosmochim. Acta 56, 1963.
4. Cronin, J.R., Pizzarello, S., 1983. Amino acids in meteorites. Adv. Space Res. 3, 5-18.
5. Cronin, J.R., Pizzarello, S., 1997. Enantiomeric excesses in meteoritic amino acids. Science 275, 951-955.
6. Cronin, J.R., Pizzarello, S., Cruikshank, D.P., 1988. Organic matter in carbonaceous chondrites, planetary satellites, asteroids and comets. In: Kerridge, J.F., Matthews, M.S. (Eds.), Meteorites and the Early Solar System. Univ. of Arizona Press, p. 819.
7. Dauwe, B., Middelburg, J.J., 1998. Amino acids and hexosamins as indicators of organic matter degradation state in North Sea sediments. Limnol. Oceanogr. 43, 782-798.
8. Dayhoff, M.O., 1972. Atlas of Protein Sequence and Structure, Vol. 5. Natl. Biomed. Res. Found., Washington, DC.
9. Dayhoff, M.O., 1978. Atlas of Protein Sequence and Structure, Vol. 5, Suppl. 3. Natl. Biomed. Res. Found., Washington, DC.
10. Engel, M.H., Macko, S.A., 1997. Isotopic evidence for extraterrestrial non-racemic amino acids in the Murchison meteorite. Nature 389, 265.
11. Engel, M.H., Nagy, B., 1982, Distribution and enantiomeric composition of amino acids in the Murchison meteorite. Nature 296, 837.
12. Engel, M.H., Macko, S.A., Silfer, J.A., 1990. Carbon isotope composition of individual amino acids in the Murchison meteorite. Nature 348, 47.
13. Horsfall, I.M., Wolff, G.A., 1997. Hydrolysable amino acids in sediments from the Porcupine Abyssal Plain, northeast Atlantic Ocean. Org. Geochem. 26, 311.
14. Keil, R.G., Tsamakis, E., Giddings, J.C., Hedges, J.I., 1998. Biochemical distributions (amino acids, neutral sugars, and lignin phenols) among size-classes of modern marine sediments from the Washington coast. Geochim. Cosmochim. Acta 62, 1347.
15. McDonald, G.D., Storrie-Lombardi, M.C., 1999. Principal component analysis for biosignature detection in extraterrestrial samples. Abs. Pap. ACS 217, GEOC-71.
16. 2O spark Tholin: chemical analysis and interaction with jovian aqueous clouds. Icarus 94, 354-367.
17. McDonald, G.D., Thompson, W.R., Heinrich, M., Khare, B.N., Sagan, C., 1994. Chemical investigation of Titan and Triton tholins. Icarus 108, 137-145.
18. Miller, S.L., 1955. Production of some organic compounds under possible primitive Earth conditions. J. Am. Chem. Soc. 77, 2351-2361.
19. Muñoz Caro, G.M., Meierhenrich, U.J., Schutte, W.A., Barbler, B., Arcones Segovia, A., Rosenbauer, H., Thiemann, W.H.-P., Brack, A., Greenberg, J.M., 2002. Amino acids from ultraviolet irradiation of interstellar ice analogues. Nature 416, 403-406.
20. Nealson, K.H., 1997. The limits of life on Earth and searching for life on Mars. J. Geophys. Res.-Planet. 102 (E10), 23675-23686.
21. Pizzarello, S., Cronin, J.R., 1988. Alanine enantiomers in the Murchison meteorite. Nature 394, 236.
22. Schlesinger, G., Miller, S.L., 1983. Prebiotic synthesis in atmospheres containing CH4, CO, and CO2. J. Mol. Evol. 19, 376-382.
23. Storrie-Lombardi, M.C., Irwin, M., von Hippel, T., 1994. Spectral classification with principal component analysis and artificial neural networks. Vistas Astron. 38, 331-340.