Case-Control Study Comparing Droperidol plus Diphenhydramine with Conventional Treatment in Hyperemesis Gravidarum

Journal of Pharmacy Technology

Volumn 19, Issue 6, 2003, Pages 349-354

  Ferreira, Ema ^a,b   Bussières, Jean François ^a,b   Turcotte, Virginie ^c   Duperron, Louise ^a   Ouellet, Geneviève ^d  

^a UNIVERSITY OF MONTREAL   (Canada)

^b UNIVERSITÉ DE MONTRÉAL   (Canada)

^c CENTRE HOSPITALIER DE L UNIVERSITÉ DE MONTRÉAL   (Canada)

^d UNIVERSITÉ LAVAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIEMETIC AGENT; ANTIHISTAMINIC AGENT; BENDECTIN; CHLORPROMAZINE; DIMENHYDRINATE; DIPHENHYDRAMINE; DOXYLAMINE; DROPERIDOL; METOCLOPRAMIDE; PYRIDOXINE;

ABORTION; ADULT; AKATHISIA; ANXIETY DISORDER; APGAR SCORE; ARTICLE; BIRTH WEIGHT; CASE CONTROL STUDY; CESAREAN SECTION; CHILL; CLINICAL TRIAL; CONGENITAL MALFORMATION; CONSTIPATION; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DISEASE SEVERITY; DROWSINESS; DRUG EFFICACY; DRUG SAFETY; DYSTONIA; EXTRAPYRAMIDAL SYMPTOM; FEMALE; HEART ARRHYTHMIA; HUMAN; HYPEREMESIS GRAVIDARUM; HYPOTENSION; LARYNX SPASM; MAJOR CLINICAL STUDY; NAUSEA; OCULOGYRIC CRISIS; PREGNANCY; PREMATURITY; PROSPECTIVE STUDY; SYMPTOMATOLOGY; TACHYCARDIA; TREATMENT OUTCOME; TREMOR; URINE RETENTION; VISUAL IMPAIRMENT; VOMITING; XEROSTOMIA;

EID: 0348141790     PISSN: 87551225     EISSN: None     Source Type: Journal    
DOI: 10.1177/875512250301900602     Document Type: Article

References (36)

1. Goodwin TM. Hyperemesis gravidarum. Clin Obstet Gynecol 1998;41:597-605.
2. Bashiri A, Neumann L, Maymon E, Katz M. Hyperemesis gravidarum: epidemiologic features, complications and outcome. Eur J Obstet Gynecol Reprod Biol 1995;63:135-8.
3. Depue RH, Bernstein L, Ross RK, Judd HL, Henderson BE. Hyperemesis gravidarum in relation to estradiol levels, pregnancy outcome, and other maternal factors: a seroepidemiologic study. Am J Obstet Gynecol 1987;157:1137-41.
4. Klebanoff MA, Koslowe PA, Kaslow R, Rhoads GG. Epidemiology of vomiting in early pregnancy. Obstet Gynecol 1985;66:612-6.
5. Nelson-Piercy C. Treatment of nausea and vomiting in pregnancy - when should it be treated and what can be safely taken? Drug Saf 1998;19:155-64.
6. Järnfelt-Samsioe A, Samsioe Velinder GM. Nausea and vomiting in pregnancy - a contribution to its epidemiology. Gynecol Obstet Invest 1983;16:221-9.
7. Baron TH, Ramirez B, Richter JE. Gastrointestinal motility disorders during pregnancy. Ann Intern Med 1993;118:366-75.
8. Hod M, Orvieti R, Kaplan B, Friedman S, Ovadia J. Hyperemesis gravidarum: a review. J Reprod Med 1994;39:605-12.
9. Mazzota P, Magge L, Koren G. Elective medical abortions due to severe morning sickness, unacceptable combination. Can Fam Physician 1997;43:1055-7.
10. Gross S, Librach C, Cecutti A. Maternal weight loss associated with hyperemesis gravidarum: a predictor of fetal outcome. Am J Obstet Gynecol 1989;160:906-9.
11. Godsey RK, Newman RB. Hyperemesis gravidarum: a comparison of single and multiple admissions. J Reprod Med 1991;36:287-90.
12. Leathem AM. Safety and efficacy of antiemetics used to treat nausea and vomiting in pregnancy. Clin Pharm 1986;5:660-8.
13. Cartwright EW. Dramamine in nausea and vomiting of pregnancy. West J Surg Obstet Gynecol 1951;59:216-34.
14. Benaron HB, Dorr EM, Roddick WJ. The use of chlorpromazine in the obstetric patient: a preliminary report. Am J Obstet Gynecol 1955;69:776-9.
15. Lebherz TB, Harris JH. Bonamine: an effective new therapy in nausea and vomiting of pregnancy. Obstet Gynecol 1955;6:606-9.
16. Seto A, Einarson T, Koren G. Pregnancy outcome following first trimester exposure to antihistamines: meta-analysis. Am J Perinatol 1997;14:119-24.
17. Nageotte MP, Briggs GG, Towers CV, Asrat T. Droperidol and diphenhydramine in the management of hyperemesis gravidarum. Am J Obstet Gynecol 1996;174:1801-6.
18. Safari H, Fassett MJ, Souter IC, Alsulyman OM, Goodwin TM. The efficacy of methylprednisolone in the treatment of hyperemesis gravidarum: a randomized, double-blind, controlled study. Am J Obstet Gynecol 1998;179:921-4.
19. Sullivan CA, Johnson CA, Roach H, Martin RW, Stewart DK, Morrison JC. A pilot study of intravenous ondansetron for hyperemesis gravidarum. Am J Obstet Gynecol 1996;174:1565-8.
20. Briggs GG. A guideline for treating hyperemesis gravidarum. Contemp Obstet Gynecol 1997;42:70-9.
21. Pettit GP, Smith GA, McIlroy WL. Droperidol, in obstetrics: a double-blind study. Mili Med 1976;141:316-7.
22. Smith AM, McNeil WT. Awareness during anesthesia. Br Med J 1969;1:572-3.
23. Seigel LJ, Long DL. The control of chemotherapy-induced emesis. Ann Intern Med 1981;95:352-9.
24. Koren G. Maternal-fetal toxicology. A clinician's guide. 3rd ed. Madison, NY: Marcel Dekker, 2001.
25. Koda-Kimble MA, Young LY. Nausea and vomiting. In: Young LY, Koda-Kimble MA, eds. Applied therapeutics: the clinical use of drugs. 6th ed. Vancouver, WA: Applied Therapeutics, 1995:105.1-11.
26. Turcotte V, Ferreira E, Duperron L. Utilité du dropéridol et de la diphenhydramine dans l'hyperemesis gravidarum. J Soc Obstet Gynaecol Can 2001;2(23):133-9.
27. Franklin HR, Simonetti PC, Dubbelman AC, ten Bokkel Huinink WW, Taal BG, Wigbout G, et al. Toxicity grading systems. A comparison between the WHO scoring system and the Common Toxicity Criteria when used for nausea and vomiting. Ann Oncol 1994;5:113-7.
28. Erez S, Schifrin BS, Dirimo O. Double-blind evaluation of hydroxyzine as an antiemetic in pregnancy. J Reprod Med 1971;7:35-7.
29. 1 histamine antagonists. Reprod Toxicol 1996;10:247-55.
30. Eliakim R, Abulafia O, Sherer DM. Hyperemesis gravidarum: a current review. Am J Perinatol 2000;17:207-18.
31. Crotti M, Aguzzoli L, Carossino E, Accorsi P, Gargano G, Masellis G. Evaluation and treatment of hyperemesis gravidarum. Minerva Ginecol 2001;53:413-9.
32. Folk JJ, Leslie HF. Hyperemesis gravidarum: pregnancy outcomes and complications among women nutritionally supported with and without parenteral therapy. Obstet Gynecol 2001;97(suppl 1):S37-42.
33. Nelson-Piercy C, Fayers P, de Swiet M. Randomized, double-blind, placebo-controlled trial of corticosteroids for the treatments of hyperemesis gravidarum. BJOG 2001;108:9-15.
34. Power ML, Holzman GB, Schulkin J. A survey of the management of nausea and vomiting in pregnancy by obstetrician/gynaecologists. Prim Care Update Ob Gyns 2001;2(Mar 8):69-72.
35. FDA Talkpaper. FDA strengthens warnings for droperidol. www. fda.gov (accessed 2002 Jan 23).
36. Santé Canada. Direction générale des produits de santé et des aliments. Mise en garde importante sur un médicament. Dropéridol www.hc-sc.gc.ca/hpb-dgps/therapeut/zfiles/french/advisory/ tpd/droperidol_f.html (accessed 2002 Feb 18).