Two novel somatic mutations in the human interleukin 6 promoter region in a patient with sporadic breast cancer

European Journal of Immunogenetics

Volumn 30, Issue 6, 2003, Pages 397-400

  Saha, A ^a   Bairwa, N K ^a   Ranjan, A ^a   Gupta, V ^a   Bamezai, R ^a  

^a JAWAHARLAL NEHRU UNIVERSITY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; TRANSCRIPTION FACTOR;

ARTICLE; BINDING SITE; BREAST CANCER; CLINICAL ARTICLE; CONTROLLED STUDY; DNA RESPONSIVE ELEMENT; FEMALE; GENE EXPRESSION; GENE SEQUENCE; GENETIC POLYMORPHISM; GLUCOCORTICOID RESPONSIVE ELEMENT; HUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; SOMATIC MUTATION; TRANSCRIPTION INITIATION SITE; TRANSLATION INITIATION;

BASE SEQUENCE; BINDING SITES; BREAST NEOPLASMS; CASE-CONTROL STUDIES; GLUCOCORTICOIDS; INTERLEUKIN-6; MOLECULAR SEQUENCE DATA; MUTATION; NF-KAPPA B; POLYMORPHISM, GENETIC; PROMOTER REGIONS (GENETICS); RESPONSE ELEMENTS;

EID: 0348140960     PISSN: 09607420     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2370.2003.00423.x     Document Type: Article

References (21)

1. Bowcock, B.M., Kidd, J.R., Lathrop, G.M., Daneshvar, L., May, L.T., Ray, A., Sehgal, P.B., Kidd, K.K. & Cavalli Sforza, L.L. (1988) The human 'interferon-β2/hepatocyte stimulating factor/ interleukin-6' gene: DNA polymorphism studies and localization to chromosome 7p21. Genomics, 3, 8.
2. Espevik, T., Waage, A., Faxvaag, A. & Shalaby, M.R. (1990) Regulation of interleukin-2 and interleukin-6 production from T-cells: involvement of interleukin-1β and transforming growth factor-β. Cell Immunology, 126, 47.
3. Frech, K., Dietze, P. & Werner, T. (1997) ConsInspector 3.0: new library and enhanced functionality. Computer Applied Bioscience, 13, 109.
4. Frech, K., Herrmann, G. & Werner, T. (1993) Computer-assisted prediction, classification, and delimitation of protein binding sites in nucleic acids. Nucleic Acids Research, 21, 1655.
5. Heinrich, P.C., Castell, J.V. & Andus, T. (1990) Interleukin-6 and the acute phase response. Biochemical Journal, 265, 621.
6. Hirano, T. (1992) The biology of interleukin-6. Chemical Immunology, 51, 153.
7. Hirano, T. (1998) Interleukin 6 and its receptor: ten years later. International Review of Immunology, 16, 249.
8. Hirano, T. & Kishimoto, T. (1990) Interleukin. In: Handbook of Experimental Pharmacology. Peptide Growth Factors and Their Receptors, (ed. M. B. Sporn & A. B. Roberts), Interleukin, 6, p. 633. Springer-Verlag, Berlin.
9. Hodgkin, P.D., Bond, M.W., O'Garra, A., Frank, G., Lee, F., Coffman, R.L., Zlotnik, A. & Howard, M. (1988) Identification of IL-6 as a T-cell-derived factor that enhances the proliferative response of thymocytes to IL-4 and phorbol myristate acetate. Journal of Immunology, 141, 151.
10. Hongyo, T., Buzard, G.S., Calvert, R.J. & Weghorst, C.M. (1993) 'Cold SSCP': a simple, rapid and non-radioactive method for optimized single-strand conformation polymorphism analyses. Nucleic Acids Research, 21, 3637.
11. Horii, Y., Muraguchi, A., Suematsu, S., Matsuda, T., Yoshizaki, K., Hirano, T. & Kishimoto, T. (1988) Regulation of BSF-2/IL-6 production by human mononuclear cells. Macrophage-dependent synthesis of BSF-2/IL-6 by T cells. Journal of Immunology, 141, 1529.
12. Kunkel, L.M., Smith, K.D., Boyer, S.H., Borgaonkar, D.S., Wachtel, S.S., Miller, O.J., Breg, W.R., Jones, H.W. Jr & Rary, J.M. (1977) Analysis of human Y-chromosome-specific reiterated DNA in chromosome variants. Proceedings of the National Academy of Sciences USA, 74, 1245.
13. Ray, A., Sassone Corsi, P. & Sehgal, P.B. (1989) A multiple cytokine-and second messenger-responsive element in the enhancer of the human interleukin-6 gene: similarities with c-fos gene regulation. Molecular and Cell Biology, 9, 5537.
14. Ray, A., Tatter, S.B., May, L.T. & Sehgal, P.B. (1988) Activation of the human 'β2-interferon/hepatocyte-stimulating factor/interleukin 6' promoter by cytokines, viruses, and second messenger agonists. Proceedings of the National Academy of Sciences USA, 85, 6701.
15. Sehgal, P.B. (1992) Regulation of IL-6 gene expression. Research in Immunology, 143, 724.
16. Sehgal, P.B., Grienger, G. & Tosato, G. (1989) Regulation of the acute phase and immune responses: interleukin-6. Annual New York Academy of Sciences, 557, 1.
17. Sehgal, P.B., Zilberstein, A., Ruggieri, R.M., Mary, L.T., Ferguson Smith, A., Slate, D.L., Revel, M. & Ruddle, F.H. (1986) Human chromosome 7 carries the beta 2 interferon gene. Proceedings of the National Academy of Sciences USA, 83, 5219.
18. Tanabe, O., Akira, S., Kamiya, T., Wong, G.G., Hirano, T. & Kishimato, T. (1988) Genomic structure of the murine IL-6 gene. High degree conservation of potential regulatory sequences between mouse and human. Journal of Immunology, 141, 3875.
19. Van Snick, J. (1990) Interleukin-6: an overview. Annual Review of Immunology, 8, 253.
20. Van Snick, J., Vink, A., Cayphas, S. & Uyttenhove, C. (1987) Interleukin-HP1, a T-cell-derived hybridoma growth factor that supports the in vitro growth of murine plasmacytomas. Journal of Experimental Medecine, 165, 641.
21. Yasukawa, K., Hirano, T., Watanabe, Y., Muratani, K., Matsuda, T., Nakai, S. & Kishimato, T. (1987) Structure and expression of human B cell stimulatory factor-2 (BSF-2/IL-6) gene. EMBO Journal, 6, 2939.