Downregulation of renal AQP2 water channel and NKCC2 in mice lacking the apical Na+-H+ exchanger NHE3

Journal of Physiology

Volumn 553, Issue 2, 2003, Pages 511-522

  Amlal, Hassane ^a,c   Ledoussal, Clara ^a   Sheriff, Sulaiman ^a   Shull, Gary E ^a   Soleimani, Manoocher ^a,b  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c Division of Oral Surgery   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETAZOLAMIDE; AQUAPORIN 2; BICARBONATE; HORMONE PRECURSOR; MESSENGER RNA; SODIUM POTASSIUM CHLORIDE COTRANSPORTER; SODIUM PROTON EXCHANGE PROTEIN 3; VASOPRESSIN; WATER; ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); AQUAPORIN 1; SODIUM POTASSIUM CHLORIDE COTRANSPORTER 2;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CIRCULATION; CONTROLLED STUDY; CORRELATION FUNCTION; DOWN REGULATION; FLUID BALANCE; FLUID TRANSPORT; IMMUNOBLOTTING; KIDNEY COLLECTING TUBULE; KIDNEY CORTEX; KIDNEY MEDULLA; KIDNEY TUBULE ABSORPTION; MOUSE; NEPHRON; NONHUMAN; NORTHERN BLOTTING; NULL ALLELE; PATHOPHYSIOLOGY; POLYDIPSIA; POLYURIA; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; STATISTICAL ANALYSIS; URINE OSMOLALITY; VASOPRESSIN BLOOD LEVEL; WATER TRANSPORT; WILD TYPE; ANIMAL TISSUE; BRAIN LEVEL; CORRELATIONAL STUDY; GENE EXPRESSION; HORMONE BLOOD LEVEL; KIDNEY; KIDNEY INNER MEDULLA; KIDNEY OUTER MEDULLA; MEDULLARY THICK ASCENDING LIMB;

ACETAZOLAMIDE; ANIMALS; AQUAPORIN 1; AQUAPORIN 2; AQUAPORINS; BLOTTING, NORTHERN; BLOTTING, WESTERN; DOWN-REGULATION; DRINKING; GENE EXPRESSION; HETEROZYGOTE; HOMOZYGOTE; HYDROGEN-ION CONCENTRATION; KIDNEY; KIDNEY CORTEX; KIDNEY MEDULLA; MICE; MICE, KNOCKOUT; NA(+)-K(+)-EXCHANGING ATPASE; OSMOLAR CONCENTRATION; POLYURIA; SODIUM; SODIUM-HYDROGEN ANTIPORTER; SODIUM-POTASSIUM-CHLORIDE SYMPORTERS; URINE; VASOPRESSINS;

EID: 0348133547     PISSN: 00223751     EISSN: None     Source Type: Journal    
DOI: 10.1113/jphysiol.2003.053363     Document Type: Article

References (36)

1. Amlal H, Chen Q, Habo K, Wang Z & Soleimani M (2001). Fasting downregulates renal. water channel AQP-2 and causes polyuria. Am J Physiol Renal Physiol 280, F513-523.
2. Amlal H, Krane CM, Chen Q & Soleimani M (2000). Early polyuria and urinary concentrating defect in potassium deprivation. Am J Physiol Renal Physiol 279, F655-663.
3. - cotransport in medullary thick ascending limb: control by PKA, PKC, and 20-HETE. Am J Physiol 271, C455-463.
4. - cotransport via 20-HETE and PKC in medullary thick ascending limb. Am J Physiol 274, C1047-1056.
5. Amlal H, Wang Z & Soleimani M (1998a). Potassium depletion downregulates chloride- absorbing transporters in rat kidney. J Clin Invest 101, 1045-1054.
6. +-dependent transporters and collecting duct aquaporins to dehydration in 7-month-old rats. Kidney Int 64, 544-554.
7. Beck N, Singh H, Reed SW, Murdaugh HV & Davis BB (1974). Pathogenic role of cyclic AMP in the impairment of urinary concentrating ability in acute hypercalcemia. J Clin Invest 54, 1049-1055.
8. +-depleted rat kidney. Am J Physiol 231, 1204-1208.
9. + transporter abundances in NHE3 and NCC null mice using targeted proteomics. J Physiol 530, 359-366.
10. Brown D, Katsura T, Kawashima M, Verkman AS & Sabolic I (1995). Cellular distribution of the aquaporins: a family of water channel proteins. Histochem Cell Biol 104, 1-9.
11. Burg MB (1976). Tubular chloride transport and the mode of action of some diuretics. Kidney Int 9, 189-197.
12. Chomczynski P & Sacchi N (1987). Single-step method of RNA isolation by acid guanidinium thiocynate-phenol-chloroform extraction. Anal Biochem 162, 156-159.
13. Church GM & Gilbert W (1984). Genomic sequencing. Proc Natl Acad Sci USA 81, 991-995.
14. Fushimi K & Marumo F (1995). Water channels. Curr Opin Nephrol Hyper 4, 392-397.
15. Fushimi K, Uchida S, Hara Y, Hirata Y, Marumo F & Sasaki S (1993). Cloning and expression of apical membrane water channel of rat kidney collecting tubule. Nature 361, 549-552.
16. Hebert SC & Andreoli TE (1984a). Control of NaCl transport in the thick ascending limb. Am J Physiol 253, F745-756.
17. - absorption J Membr Biol 80, 221-233.
18. Hebert SC, Culpepper RM & Andreoli TE (1981). NaCl transport in mouse medullary thick ascending limbs. I. Functional nephron heterogeneity and ADH-stimulated NaCl cotransport. Am J Physiol 241, F412-431.
19. Igarashi P, Whyte DA, Li K & Nagami GT (1996). Cloning and kidney cell-specific activity of the promoter of the murine renal Na-K-Cl cotransporter gene. J Biol Chem 271, 9666-9674.
20. Kim G, Ecelbarger CA, Mitchell C, Packer RK, Wade JB & Knepper MA (1999). Vasopressin increases Na-K-2Cl cotransporter expression in thick ascending limb of Henle's loop. Am J Physiol 276, F96-103.
21. Knepper MA (1997). Molecular physiology of urinary concentrating mechanism: Regulation of aquaporin water channels by vasopressin. Am J Physiol 272, F3-12.
22. Knepper MA & Rector FC (1996a). Urine concentration and dilution. In The Kidney: Diagnosis and Treatment, 5th edn, vol. 1, ed. Brenner BM & Rector FC, pp. 532-570. Saunders WB, Philadelphia.
23. Knepper MA, Wade JB, Terris J, Ecelbarger CA, Marples D, Mandon B, Chou CL, Kishore BK & Nielsen S (1996b). Renal aquaporins. Kidney Int 49, 1712-1717.
24. + exchanger has no apparent effect on diarrheal state of NHE3-deficient mice. Am J Physiol Gastrointest Liver Physiol 281, G1385-1396.
25. Maeda Y, Smith BL, Agre P & Knepper MA (1995). Quantification of Aquaporin-CHIP water channel protein in microdissected renal tubules by fluorescence-based ELISA. J Clin Invest 95, 422-428.
26. - reabsorption in renal collecting duct of NHE-3-deficient mouse: a compensatory response. Am J Physiol 276, F914-921.
27. Nielsen S, Chou CL, Marples D, Christensen EI, Kishore BK & Knepper MA (1995). Vasopressin increases water permeability of kidney collecting duct by inducing translocation of aquaporin-CD water channels to plasma membrane. Proc Natl Acad Sci U S A 92, 1013-1017.
28. Nielsen S, Digiovanni SR, Christensen EI, Knepper MA & Harris HW (1993b). Cellular and subcellular immunolocalization of vasopressin-regulated water channel in rat kidney. Proc Natl Acad Sci U S A 90, 11663-11667.
29. Nielsen S, Maunsbach AB, Ecelbarger CA & Knepper MA (1998). Ultrastructural localization of Na-K-2Cl cotransporter in thick ascending limb and macula densa of rat kidney. Am J Physiol 275, F885-893.
30. Nielsen S, Smith BL, Christensen EI, Knepper MA & Agre P (1993a). CHIP28 water channels are localized in constitutively water-permeable segments of the nephron. J Cell Biol 120, 371-383.
31. Sabolic I, Valenti G, Verbavatz JM, Van Hoek AN, Verkman AS, Ausiello DA & Brown D (1992). Localization of the CHIP28 water channel in rat kidney. Am J Physiol 263, C1225-1233.
32. Sands JM & Kokko JP (1996). Current concepts of the countercurrent multiplication system. Kidney Int Suppl 57, S93-99.
33. + exchanger. Nat Genet 19, 282-285.
34. Schwartz MJ & Kokko JP (1980). Urinary concentrating defect of adrenal insufficiency. Permissive role of adrenal steroids on the hydroosmotic response across the rabbit cortical collecting tubule. J Clin Invest 166, 234-242.
35. Uchida S, Sasaki S, Fushimi K & Marumo F (1994). The isolation of human aquaporin-CD gene. J Biol Chem 269, 23451-23455.
36. Work J & Jamison RL (1987). Effect of adrenalectomy on transport in the rat medullary thick ascending limb. J Clin Invest 80, 1160-1164.