Direct in vivo screening of intrabody libraries constructed on a highly stable single-chain framework

Journal of Biological Chemistry

Volumn 277, Issue 47, 2002, Pages 45075-45085

  Auf der Maur, Adrian ^a   Zahnd, Christian ^b   Fischer, Franziska ^a   Spinelli, Silvia ^c   Honegger, Annemarie ^b   Cambillau, Christian ^b   Escher, Dominik ^a   Plückthun, Andreas ^b   Barberis, Alcide ^a  

^a ESBATech AG   (Switzerland)

^b UNIVERSITY OF ZURICH   (Switzerland)

^c CNRS   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODIES; ANTIGEN-ANTIBODY REACTIONS; CHEMICAL BONDS; GENES; MUTAGENESIS; SULFUR;

INTRABODY LIBRARIES;

BIOCHEMISTRY;

ANTIBODY; PEPTIDE LIBRARY; SINGLE CHAIN FRAGMENT VARIABLE ANTIBODY;

AMINO ACID SEQUENCE; ANTIBODY ISOLATION; ANTIBODY STRUCTURE; ANTIGEN SPECIFICITY; ARTICLE; CONTROLLED STUDY; DISULFIDE BOND; GENOMICS; IN VIVO STUDY; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN STABILITY;

AMINO ACID SEQUENCE; ANTIGENS; BINDING SITES, ANTIBODY; DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION; GENES, IMMUNOGLOBULIN; GENES, REPORTER; HUMANS; IMMUNOGLOBULIN FRAGMENTS; IMMUNOGLOBULIN VARIABLE REGION; LEUCINE ZIPPERS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; PEPTIDE LIBRARY; PROTEIN BINDING; PROTEIN FOLDING; PROTEIN KINASES; PROTEIN STRUCTURE, TERTIARY; PROTO-ONCOGENE PROTEINS C-JUN; RECOMBINANT FUSION PROTEINS; SACCHAROMYCES CEREVISIAE PROTEINS; SEQUENCE ALIGNMENT; TRANS-ACTIVATORS; TRANSCRIPTION, GENETIC; TWO-HYBRID SYSTEM TECHNIQUES; YEASTS;

EUKARYOTA; PROKARYOTA;

EID: 0347997286     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M205264200     Document Type: Article

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