Absorption, distribution and excretion of 14C-chloroquine after single oral administration in albino and pigmented rats: Binding characteristics of chloroquine-related radioactivity to melanin in-vivo

Journal of Pharmacy and Pharmacology

Volumn 55, Issue 12, 2003, Pages 1647-1654

  Ono, Chiho ^a   Yamada, Masayoshi ^a   Tanaka, Makoto ^a  

^a DAIICHI SANKYO CO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CHLOROQUINE C 14; DRUG METABOLITE; MELANIN; RADIOPHARMACEUTICAL AGENT; UNCLASSIFIED DRUG;

ALBINISM; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DRUG ABSORPTION; DRUG BINDING; DRUG DISPOSITION; DRUG DISTRIBUTION; DRUG EXCRETION; DRUG HALF LIFE; DRUG TISSUE LEVEL; DRUG UPTAKE; HAIR FOLLICLE; HYDROPHOBICITY; IN VIVO STUDY; MALE; NONHUMAN; PIGMENTATION; RADIOACTIVITY; RAT; SERUM; SINGLE DRUG DOSE; UVEA;

ADMINISTRATION, ORAL; ANIMALS; ANTIMALARIALS; AUTORADIOGRAPHY; CHLOROQUINE; INTESTINAL ABSORPTION; MALE; MELANINS; RATS; SPECIES SPECIFICITY; TISSUE DISTRIBUTION;

EID: 0347989310     PISSN: 00223573     EISSN: None     Source Type: Journal    
DOI: 10.1211/0022357022340     Document Type: Article

References (11)

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