Anthelminthic and Antiallergic Activities of Mangifera indica L. Stem Bark Components Vimang and Mangiferin

Phytotherapy Research

Volumn 17, Issue 10, 2003, Pages 1203-1208

  Garcia D ^a   Escalante, M ^b   Delgado, R ^b   Ubeira, F M ^b   Leiro, J ^b  

^a Centro de Quimica Farmaceutica   (Cuba)

^b UNIVERSITY OF SANTIAGO DE COMPOSTELA   (Spain)

Author keywords

Anthelminth; Cutaneous anaphylaxis; IgE; Mangiferin; Trichinella spiralis; Vimang

Indexed keywords

ANTHELMINTIC AGENT; ANTIALLERGIC AGENT; IMMUNOGLOBULIN E; MANGIFERA INDICA EXTRACT; MANGIFERIN; UNCLASSIFIED DRUG; VIMANG;

ALLERGY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTHELMINTIC ACTIVITY; ANTIBODY TITER; ARTICLE; BARK; BODY WEIGHT; CHEMICAL COMPOSITION; CONTROLLED STUDY; CYTOSOL; DIAGNOSTIC VALUE; EVALUATION; LARVAL DEVELOPMENT; LIFE CYCLE; MALE; MANGO; MAST CELL DEGRANULATION; MEDICINAL PLANT; MOUSE; MUSCLE TISSUE; NEMATODE; NONHUMAN; PARASITE; PASSIVE SKIN ANAPHYLAXIS; PLANT STEM; RAT; SENSITIZATION; TRICHINELLA SPIRALIS;

ADMINISTRATION, ORAL; ANAPHYLAXIS; ANIMALS; ANTHELMINTICS; ANTI-ALLERGIC AGENTS; ANTIBODIES, HELMINTH; DOSE-RESPONSE RELATIONSHIP, DRUG; LARVA; MALE; MANGIFERA; MICE; MICE, INBRED BALB C; PHYTOTHERAPY; PLANT EXTRACTS; PLANT STEMS; RATS; TRICHINELLA SPIRALIS; TRICHINOSIS; XANTHONES;

MANGIFERA; MANGIFERA INDICA; TRICHINELLA SPIRALIS;

EID: 0347987008     PISSN: 0951418X     EISSN: None     Source Type: Journal    
DOI: 10.1002/ptr.1343     Document Type: Article

References (53)

1. Ahmad A, Wang CH, Bell RG. 1991. A role for IgE in intestinal immunity. Expression of rapid expulsion of Trichinella spiralis in rats transfused with IgE and thoracic duct lymphocytes. J Immunol 146: 3563-3570.
2. Awe SO, Olajide OA, Oladiran OO, Makinde JM. 1998. Antiplasmodial and antipyretic screening of Mangifera indica extract. Phytother Res 12: 437-438.
3. Baltar P, Leiro J, Santamarina MT, et al. 1991. Specific immunosuppression by Trichinella: Fine specificity and effect on lymphocyte function in vivo. Parasitology 102: 411-418.
4. Behnke JM, Wahid FN, Grencis RK, et al. 1993. Immunological relationships during primary infection with Helignosomoides polygyrus (Nematospiroides dubius): dowregulation of specific cytokine secretion (IL-9 and IL-10) correlates with poor mastocytosis and chronic survival of adult worms. Par Immunol 15: 415-421.
5. Campbell WC, Cuckler AC. 1964. Effect of thiabendazole upon the enteral and parenteral phases of trichinosis in mice. J Parasitol 50: 481-488.
6. Center of Pharmaceutical Chemistry. 1998. Pharmaceutical compositions including a mixture of polyphenols, terpenoids, steroids, fatty acids and microelements with antioxidant, analgesic, anti-inflammatory and antispasmodic properties. Patent Pending 203/98, OCPI. Havana. Cuba.
7. Coe FG, Anderson GJ. 1996. Screening of medical plants used by Garifuna of Eastern Nicaragua for bioactive compounds. J Ethnopharmacol 53: 29-50.
8. Das PC, Das A, Mandal S. 1989. Anti-inflammatory and antimicrobial activities of the seed kernel of Mangifera indica extract. Phytother Res LX: 235-240.
9. Dea-Ayuela M, Rodero M, Rodriguez-Bueno R, et al. 1999. Modulation by Anapsos (Polypodium leucotomos extract) of the antibody responses against the nematode parasite Trichinella spiralis. Phytother Res 13: 566-570.
10. Delgado R, Garrido G, Gonzalez D, et al. 2001. Mangifera indica L. extract (Vimang) as a natural antioxidant with antinociceptive and antiinflammatory properties. Minerva Med 92: 98-102.
11. Dokka S, Shi X, Leonard S, et al. 2001. Interleukin-10 mediated inhibition of free radical generation in macrophages. Am J Physiol Lung Cell Mol Physiol 280: L1196-L1202.
12. Donaldson LE, Schmitt E, Huntley JF, et al. 1996. A critical role for stem cell factor and c-kit in host protective immunity to an intestinal helminth. Int Immunol 8: 559-567.
13. Duan H, Takaishi Y, Momota H, et al. 1999. Immunosuppressive diterpenoids from Tripterygium wilfordii. J Nat Prod 62: 1522-1525.
14. Duan H, Takaishi Y, Momota H, et al. 2001. Immunosuppressive sesquiterpene alkaloids from Tripterygium wilfordii. J Nat Prod 64: 582-587.
15. Faulkner H, Humphreys N, Renauld JC, et al. 1997. Interleukin-9 is involved in host protective immunity to intestinal nematode infection. Eur J Immunol 27: 2536-2540.
16. Fleshner M, Deak T, Nguyen KT, et al. 2001. Endogenous glucocorticoids play a positive regulatory role in the anti-keyhole limpet hemocyanin in vitro antibody response. J Immunol 166: 3813-3819.
17. García D, Delgado R, Ubeira FM, Leiro J. 2002. Modulation of rat macrophage function by the Mangifera indica L. extracts Vimang and mangiferin. Int Immunopharmacol 2: 797-806.
18. Garrido G, Gonźalez D, Delporte C, et al. 2001. Analgesic and anti-inflammatory effects of Mangifera indica L. extract (Vimang). Phytother Res 15: 18-21.
19. Guha S, Ghosal S, Chattopadhyay U. 1996. Antitumor, immunomodulatory and anti-HIV effect of mangiferin, a naturally glucosylxanthone. Chemotherapy 42: 443-451.
20. Katiyar SK, Challa A, McCormick TS, et al. 1999. Prevention of UVB-induced immunosuppression in mice by the green tea polyphenol (-)-epigallocatechin-3-gallate may be associated with alterations in IL-10 and IL-12 production. Carcinogenesis 20: 2117-2124.
21. Kawada N, Seki S, Inoue M, Kuroki T. 1998. Effect of antioxidants, resveratrol, quercetin, and N-acetylcysteine, on the functions of cultured rat hepatic stellate cels and Kupffer cells. Hepatology 27: 1265-1274.
22. La Rosa G, Pozio E, Rossi P, Murrell KD. 1992. Allozyme analysis of Trichinella isolates from various host species and geographical regions. J Parasitol 78: 641-646.
23. Leiro J, Santamarina MT, Sernández L, et al. 1989. The effect of cyclosporine A on murine trichinellosis. Parasitol Res 75: 330-332.
24. Li H, Miyahara T, Tezuka Y, et al. 1998. The effect of Kampo formulae on bone resorption in vitro and in vivo. I. Active constituents of Tsu-kan-gan. Biol Pharm Bull 21: 1322-1326.
25. López-García ML, Torrado S, Torrado S, et al. 1998. Methimazole-mediated enhancement of albendazole oral bioavailability of Trichinella spiralis in mice: the influence of the dose-regime. Vet Parasitol 75: 209-219.
26. Lawrence CE, Paterson JC, Wei XQ, et al. 2000. Nitric oxide mediates intestinal pathology but not immune expulsion during Trichinella spralis infection in mice. J Immunol 164: 4229-4234.
27. Lowry OH, Rosenbrough NJ, Farr AL, Randall RS. 1951. Protein measurement with the Folin phenol reagent. J Biol Chem 193: 265-275.
28. Martín MJ, Jiménez MD, Motilva V. 2001. New issues about nitric oxide and its effects on the gastrointestinal tract. Curr Pharm Des 7: 881-908.
29. Martinez G, Delgado R, Pérez G, et al. 2000. Evaluation of the in vitro antioxidant activity of Mangifera indica L. extract (Vimang). Phytother Res 14: 424-427.
30. Modra J, Piedrafita D, Roberts MC, et al. 2000. Secretion of IL-12 by murine macrophages activated by immunoglobulin receptor-mediated internalization of the surface coat of Trichinella spiralis larvae. Par Immunol 22: 115-120.
31. Moreira RR, Carlos IZ, Vilega W. 2001. Release of intermediate reactive hydrogen peroxide by macrophage cells activated by natural products. Biol Pharm Bull 24: 201-204.
32. Negrao-Correa D, Adams LS, Bell RG. 1999. Variability of the intestinal immunoglobulin E response of rats to infection with Trichinella spiralis, Heligmosomoides polygyrus or Nippostrongylus brazilinesis. Par Immunol 21: 287-297.
33. Núñez Sellés AJ, Vélez Castro HT, et al. 2002. Isolation and quantitation analysis of phenolic antioxidants, free sugars and polyols from mango (Mangifera indica L.) stem bark aqueous decoction used in Cuba as a nutritional supplement. J Agric Food Chem 50: 762-766.
34. Pan M-H, Lin-Shiau S-H, Ho C-T, et al. 2000. Suppression of lipopolysaccharide-induced nuclear factor-κB activity by theaflavin-3-3′-digallate from black tea and other polyphenols through down-regulation of I′B kinase activity in macrophages. Biochem Pharmacol 59: 357-367.
35. Parkhouse RME. 1989. Trichinella spiralis: a model parasite. In Trichinellosis, Tanner CE (ed.). Proceedings of the Seventh International Conference on Trichinellosis. Consejo Superior de Investigaciones Científicas Press: Madrid; 13-17.
36. Pozio E, La Rosa G, Murrel D, Lichtenfels R. 1992. Taxonomic revision of the genus Trichinella. J Parasitol 78: 654-659.
37. Sánchez GM, Delgado R, Pérez G, et al. 2000a. Evaluation of the in vitro antioxidant activity of Mangifera indica L. extract (Vimang). Phytother Res 14: 424-427.
38. Sánchez GM, Re L, Giuliani A, et al. 2000b. Protective effects of Mangifera indica L. extract, mangiferin and selected antioxidants against TPA-induced biomolecules oxidation and peritoneal macrophage activation in mice. Pharmacol Res 42: 565-573.
39. Sanmartin ML, Santamarina MT, Ubeira FM. 1986. Effect of clofibrate and hydrocortisone on intestinal trichinellosis in mice. Vet Parasitol 21: 55-60.
40. Santamarina MT, Leiro J, Alvarez F, et al. 1988a. Allergenic cross-reactivity of several strains of Trichinella in mice and rats by the passive cutaneous anaphylaxis technique. Int Archs Allergy appl Immunol 85: 123-126.
41. Santamarina MT, Leiro J, Garrido MJ, et al. 1988b. The effect of the intestinal worms and migrating L1 larvae of Trichinella spiralis on the production of antiparasitic IgE antibodies. Parasitol Res 74: 581-585.
42. Santamarina MT, Leiro J, Baltar P, et al. 1993. Requirements for the induction of cross-reactive anti-Trichinella IgE antibodies in mice. Parasitol Res 79: 63-66.
43. Spaldonova R, Cerman J, Corba J, Velebny S. 1981. Allergenic reactions of the host after treatment of experimental trichinellosis, In Trichinellosis Kim CW, Ruitenberg EJ, Teppema JS (eds). Reedbooks: Chertsey; 327-329.
44. Tachibana H, Kubo T, Miyase T, et al. 2001. Identification of an inhibitor for interleukin 4-induced epsilon germline transcription and antigen-specific IgE production in vivo. Biochem Biophys Res Commun 280: 53-60.
45. Tona L, Kambu K, Ngimbi N, et al. 2000, Antiamoebic and spasmolytic activities of extracts from some antidiarrhoeal traditional preparations used in Kinshasa, Congo. Phytomedicina 7: 31-38.
46. Ubeira FM, Leiro J, Santamarina MT, et al. 1987. Immune response to Trichinella epitopes: the antiphosphorylcholine plaque-forming cell response during the biological cycle. Parasitology 94: 543-553.
47. Urban JF, Jr, Schopf L, Morris SC, et al. 2000. State signaling promotes protective immunity against Trichinella spiralis through a mast cell- and T cell-dependent mechanism, J Immunol 164: 2046-2052.
48. Wang CH, Richards EM, Bell RG. 1999. Rapid anti-helminthic response of B lymphocytes in the intestinal mucosal tissues of rats. Cell Immunol 193: 59-70.
49. Wang ZX, Takamoto M, Sugane K. 2000. Costimulatory signal through CD86 is important in Th2 response in Trichinella spiralis infected mice. Par Immunol 22: 121-130.
50. Yoosook C, Bunyapraphatsara N, Boonyakiat Y, Kantasuk C. 2000. Anti-Herpex simplex virus activities of crude water extracts of Thai medicinal plants. Phytomedicine 6: 411-419.
51. Yoshimi N, Matsunaga K, Katayama M, et al. 2001. The inhibitory effects of mangiferin, a naturally occurring glucosylxanthone, in bowel carcinogenesis of male F344 rats, Cancer Lett 163: 163-170.
52. Zheng MS, Lu ZY, 1990. Antiviral effect of mangiferin and isomangiferin on Herpex simplex virus. Chin Med J 103: 160-165.
53. Zhong M, Cheng GF, Wang WJ, et al. 1999. Inhibitory effect of resveratol on interleukin 6 release by stimulated peritoneal macrophages of mice. Phytomedicine 6: 79.