Preoperative leuprolide acetate combined with Interceed* optimally reduces uterine adhesions and fibrosis in a rabbit model

Fertility and Sterility

Volumn 81, Issue 1, 2004, Pages 194-197

  Marshburn, Paul B ^a   Meek, James M ^a   Gruber, Helen E ^a   Gordon, Brian E ^a   Norton, James H ^a   Hurst, Bradley S ^a  

^a CAROLINAS MEDICAL CENTER   (United States)

Author keywords

Adhesion; Fibrosis; GnRH a; Hypo estrogenism; Interceed; Leuprolide acetate; Oxidized regenerated cellulose; Rabbit; Uterus

Indexed keywords

LEUPRORELIN; OXIDIZED REGENERATED CELLULOSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CAUTERIZATION; CONTROLLED STUDY; DRUG EFFICACY; FEMALE; FIBROSIS; HISTOPATHOLOGY; NONHUMAN; POSTOPERATIVE COMPLICATION; PREOPERATIVE TREATMENT; PRIORITY JOURNAL; RABBIT; TREATMENT OUTCOME; UTERUS FIBROSIS; UTERUS HORN; UTERUS SURGERY; UTERUS SYNECHIA;

EID: 0347986533     PISSN: 00150282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fertnstert.2003.07.009     Document Type: Article

References (9)

1. Mais V., Ajossa S., Piras B., Guerriero S., Marongiu D., Melis G.B. Prevention of de novo adhesion formation after laparoscopic myomectomy a randomized trial to evaluate the effectiveness of an oxidized regenerated cellulose absorbable barrier . Hum Reprod. 10:1995;3133-3135.
2. Grow D.R., Coddington C.C., Hsiu J.G., Mikich Y., Hodgen G.D. Role of hypoestrogenism or sex steroid antagonism in adhesion formation after myometrial surgery in primates. Fertil Steril. 66:1996;140-146.
3. Boyers S.P., Diamond M.P., DeCherney A.H. Reduction of postoperative pelvic adhesions in the rabbit with Gore-Tex surgical membrane. Fertil Steril. 49:1988;1066-1070.
4. Zanagnolo V., Dharmarajan A.M., Hesla J., Wallach E.E. Effects of gonadotropin releasing hormone analog on rabbit ovarian function. Endocrinology. 137:1996;5400-5406.
5. Cross S.S. Grading and scoring in histopathology. Histopathology. 33:1998;99-106.
6. Diggle P.J., Liang K.Y., Zeger L.L. Analysis of longitudinal data. 1995;Oxford Science Publications, Oxford, United Kingdom.
7. Sharpe-Timms K.L., Zimmer R.L., Jolliff W.J., Wright J.A., Nothnick W.B., Curry T.E. Gonadotropin-releasing hormone agonist (GnRH-a) therapy alters activity of plasminogen activators, matrix metalloproteinases, and their inhibitors in rat models for adhesion formation and endometriosis potential GnRH-a-regulated mechanisms reducing adhesion formation . Fertil Steril. 69:1998;916-923.
8. Wiseman D.M., Gottlick-Iarkowski L., Kamp L. Effect of different barriers of oxidized regenerated cellulose (ORC) on cecal and sidewall adhesions in the presence and absence of bleeding. J Invest Surg. 12:1999;141-146.
9. Cumming D.C., Honore L.H., Scott J.Z., Williams K.E. Microscopic evidence of silent inflammation in grossly normal fallopian tubes with ectopic pregnancy. Int J Fertil. 33:1988;324-328.