Are the rules for research with subjects with dementia changing? Views from the field

Neurology

Volumn 61, Issue 12, 2003, Pages 1649-1651

  Stocking, Carol B ^a,b   Hougham, Gavin W ^a   Baron, Aliza R ^a   Sachs, Greg A ^a  

^a UNIVERSITY OF CHICAGO   (United States)

^b UNIVERSITY OF CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CLINICAL RESEARCH; DECISION MAKING; DEMENTIA; HUMAN; PATIENT RIGHT; PHYSICIAN ATTITUDE; POLICY; PRIORITY JOURNAL; RESPONSIBILITY; REVIEW;

EID: 0347951406     PISSN: 00283878     EISSN: None     Source Type: Journal    
DOI: 10.1212/01.WNL.0000098888.97357.06     Document Type: Review

References (10)

1. Dresser R. Mentally disabled research subjects: the enduring policy issues. JAMA 1996;276:67-72.
2. Capron AM. Ethical and human-rights issues in research on mental disorders that may affect decision-making capacity. N Engl J Med 1999;340:1430-1434.
3. National Bioethics Advisory Commission. Research involving persons with mental disorders that may affect decisionmaking capacity. Vol. 1. Report and recommendations of the National Bioethics Advisory Commission. Rockville: US Government Printing Office, 1998.
4. Alzheimer's Association. Ethical issues in dementia research: position of the Alzheimer's Association. 1997; available at http://www.alz.org/ AboutUs/PositionStatements/overview.html. Accessed July 23, 2003.
5. American Geriatrics Society Ethics Committee. Informed consent for research on human subjects with dementia. J Am Geriatr Soc 1998;46:1308-1310.
6. Wendler D, Prasad K. Core safeguards for clinical research with adults who are unable to consent. Ann Intern Med 2001;135:514-523.
7. Stocking CB, Hougham GW, Baron AR, Sachs GA. Ethics reporting in publications about research with Alzheimer's disease patients. J Am Geriatr Soc (in press).
8. High D. Advancing research with Alzheimer disease subjects: investigators' perceptions and ethical issues. Alzheimer Dis Assoc Disord 1993;7:165-178.
9. Karlawish J, Knopman D, Clark C, et al. Informed consent for Alzheimer's disease clinical trials: a survey of clinical investigators. IRB: Ethics Hum Res 2002;24:1-5.
10. Wendler D, Martinez R, Fairclough D, Sunderland T, Emanuel E. Views of potential subjects toward proposed regulations for clinical research with adults unable to consent. Am J Psychiatry 2002;159:585-591.