Prevalence of HSP47 antigen and autoantibodies to HSP47 in the sera of patients with mixed connective tissue disease

Biochemical and Biophysical Research Communications

Volumn 303, Issue 2, 2003, Pages 413-418

  Yokota, Shin Ichi ^a   Kubota, Hiroshi ^b   Matsuoka, Yasuhiro ^b   Naitoh, Motoko ^b   Hirata, Daisuke ^c   Minota, Seiji ^c   Takahashi, Hiroki ^a   Fujii, Nobuhiro ^a   Nagata, Kazuhiro ^b  

^a SAPPORO MEDICAL UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b KYOTO UNIVERSITY   (Japan)

^c JICHI MEDICAL UNIVERSITY   (Japan)

Author keywords

Autoantibody; ELISA; Fibrosis; HSP47; Mixed connective tissue disease; Rheumatic autoimmune disease

Indexed keywords

AUTOANTIBODY; BIOLOGICAL MARKER; HEAT SHOCK PROTEIN 47;

ARTICLE; BLOOD; CLINICAL ARTICLE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FIBROSIS; HUMAN; IMMUNOBLOTTING; MIXED CONNECTIVE TISSUE DISEASE; PRIORITY JOURNAL; RHEUMATOID ARTHRITIS; SERUM; SJOEGREN SYNDROME; SYSTEMIC LUPUS ERYTHEMATOSUS; UPREGULATION;

EID: 0347926386     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-291X(03)00352-8     Document Type: Article

References (32)

1. Nagata K. Hsp47: a collagen-specific molecular chaperone. Trends Biochem. Sci. 21:1996;22-26.
2. Nagai N., Hosokawa M., Itohara S., Adachi E., Matsushita T., Hosokawa N., Nagata K. Embryonic lethality of molecular chaperone hsp47 knockout mice is associated with defects in collagen biosynthesis. J. Cell Biol. 150:2000;1499-1506.
3. Tasab M., Batten M.R., Bulleid N.J. Hsp47: a molecular chaperone that interacts with and stabilizes correctly-folded procollagen. EMBO J. 19:2000;2204-2211.
4. Nakai A., Hirayoshi K., Nagata K. Transformation of BALB/3T3 cells by simian virus 40 causes a decreased synthesis of a collagen-binding heat-shock protein (hsp47). J. Biol. Chem. 265:1990;992-999.
5. Natsume T., Koide T., Yokota S., Hirayoshi K., Nagata K. Interactions between collagen-binding stress protein HSP47 and collagen. Analysis of kinetic parameters by surface plasmon resonance biosensor. J. Biol. Chem. 269:1994;31224-31228.
6. Koide T., Takahara Y., Asada S., Nagata K. Xaa-Arg-Gly triplets in the collagen triple helix are dominant binding sites for the molecular chaperone HSP47. J. Biol. Chem. 277:2002;6178-6182.
7. Koide T., Aso A., Yorihuzi T., Nagata K. Conformational requirements of collagenous peptides for recognition by the chaperone protein HSP47. J. Biol. Chem. 275:2000;27957-27963.
8. Iwashita T., Kadota J., Naito S., Kaida H., Ishimatsu Y., Miyazaki M., Ozono Y., Kohno S. Involvement of collagen-binding heat shock protein 47 and procollagen type I synthesis in idiopathic pulmonary fibrosis: contribution of type II pneumocytes to fibrosis. Hum. Pathol. 31:2000;1498-1505.
9. Kuroda K., Tsukifuji R., Shinkai H. Increased expression of heat-shock protein 47 is associated with overproduction of type I procollagen in systemic sclerosis skin fibroblasts. J. Invest. Dermatol. 111:1998;1023-1028.
10. Razzaque M.S., Ahsan N., Taguchi T. Heat shock protein 47 in renal scarring. Nephron. 86:2000;339-341.
11. Naitoh M., Hosokawa N., Kubota H., Tanaka T., Shirane H., Sawada M., Nishimura Y., Nagata K. Upregulation of HSP47 and collagen type III in the dermal fibrotic disease, keloid. Biochem. Biophys. Res. Commun. 280:2001;1316-1322.
12. Masuda H., Fukumoto M., Hirayoshi K., Nagata K. Coexpression of the collagen-binding stress protein HSP47 gene and the α 1(I) and α 1(III) collagen genes in carbon tetrachloride-induced rat liver fibrosis. J. Clin. Invest. 94:1994;2481-2488.
13. Razzaque M.S., Hossain M.A., Kohno S., Taguchi T. Bleomycin-induced pulmonary fibrosis in rat is associated with increased expression of collagen-binding heat shock protein (HSP) 47. Virchows Arch. 432:1998;455-460.
14. Moriyama T., Kawada N., Ando A., Yamauchi A., Horio M., Nagata K., Imai E., Hori M. Up-regulation of HSP47 in the mouse kidneys with unilateral ureteral obstruction. Kidney Int. 54:1998;110-119.
15. Sakawa A., Yutani Y., Inui K., Shimazu A., Yamano Y., Kinoshita Y., Suzuki F., Hattori T., Takigawa M. Specific serum antibodies against membranous proteins of a human immortal chondrocytic cell line (HCS-2/8) in rheumatoid arthritis and their relationship to the natural history of this disease. J. Bone Miner. Metab. 14:1996;146-152.
16. Hattori T., Fujisawa T., Sasaki K., Yutani Y., Nakanishi T., Takahashi K., Takigawa M. Isolation and characterization of a rheumatoid arthritis-specific antigen (RA-A47) from a human chondrocytic cell line (HCS-2/8). Biochem. Biophys. Res. Commun. 245:1998;679-683.
17. Hattori T., Takahash K., Yutani Y., Fujisawa T., Nakanishi T., Takigawa M. Rheumatoid arthritis-related antigen 47. kDa (RA-A47) is a product of colligin-2 and acts as a human HSP47 J. Bone Miner. Metab. 18:2000;328-334.
18. Yokota S., Hirata D., Minota S., Higashiyama T., Kurimoto M., Yanagi H., Yura T., Kubota H. Autoantibodies against chaperonin CCT in human sera with rheumatic autoimmune diseases: comparison with antibodies against other Hsp60 family proteins. Cell Stress Chaperones. 5:2000;337-346.
19. 1/S transition through early S phase J. Biol. Chem. 274:1999;37070-37078.
20. El-Thaher S.H., Drake A.F., Yokota S., Nakai A., Nagata K., Miller A.D. The pH-dependent, ATP-independent interaction of collagen specific serpin/stress protein HSP47. Protein Peptide Lett. 3:1996;1-8.
21. Saga S., Nagata K., Chen W.T., Yamada K.M. pH-dependent function, purification, and intracellular location of a major collagen-binding glycoprotein. J. Cell Biol. 1055:1987;17-27.
22. Kasukawa R., Tojo T., Miyawaki S. Preliminary diagnostic criteria for classification of mixed connective tissue disease. Kasukawa R., Sharp G.C. Mixed Connective Tissue Diseases and Antinuclear Antibodies. 1987;41-47 Elsevier, Amsterdam.
23. Kasukawa R. Mixed connective tissue disease. Internal Med. 38:1999;386-393.
24. Appelboom T., Kahn M.F., Mairesse N. Antibodies to small ribonucleoprotein and to 73-kDa heat shock protein: two distinct markers of mixed connective tissue disease. Clin. Exp. Immunol. 100:1995;486-488.
25. Mairesse N., Kahn M.F., Appelboom T. Antibodies to the constitutive 73-kDa heat shock protein: a new marker of mixed connective tissue disease? Am. J. Med. 95:1993;595-600.
26. Houtman P.M., Kallenberg C.G., Limburg P.C., van Leeuwen M.A., van Rijswijk M.H., The T.H. Fluctuations in anti-nRNP levels in patients with mixed connective tissue disease are related to disease activity as part of a polyclonal B cell response. Ann. Rheum. Dis. 45:1986;800-808.
27. Hoet R.M., Koornneef I., de Rooij D.J., van de Putte L.B., van Venrooij W.J. Changes in anti-U1 RNA antibody levels correlate with disease activity in patients with systemic lupus erythematosus overlap syndrome. Arthritis Rheum. 35:1992;1202-1210.
28. Smolen J.S., Steiner G. Mixed connective tissue disease: to be or not to be? Arthritis Rheum. 41:1998;768-777.
29. Satoh M., Hirayoshi K., Yokota S., Hosokawa N., Nagata K. Intracellular interaction of collagen-specific stress protein HSP47 with newly synthesized procollagen. J. Cell Biol. 133:1996;469-483.
30. Eggleton P., Llewellyn D.H. Pathophysiological roles of calreticulin in autoimmune disease. Scand. J. Immunol. 49:1999;466-473.
31. Routsias J.G., Tzioufas A.G., Sakarellos-Daitsiotis M., Sakarellos C., Moutsopoulos H.M. Calreticulin synthetic peptide analogues: anti-peptide antibodies in autoimmune rheumatic diseases. Clin. Exp. Immunol. 91:1993;437-441.
32. Kishore U., Sontheimer R.D., Sastry K.N., Zappi E.G., Hughes G.R., Khamashta M.A., Reid K.B., Eggleton P. The systemic lupus erythematosus (SLE) disease autoantigen-calreticulin can inhibit C1q association with immune complexes. Clin. Exp. Immunol. 108:1997;181-190.