Chiral Copper Complexes of Phosphino Sulfenyl Ferrocenes as Efficient Catalysts for Enantioselective Formal Aza Diels-Alder Reactions of N-Sulfonyl Imines

Journal of the American Chemical Society

Volumn 126, Issue 2, 2004, Pages 456-457

  Mancheño, Olga García ^a   Arrayás, Ramón Gómez ^a   Carretero, Juan C ^a  

^a UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

COPPER COMPLEX; FERROCENE DERIVATIVE; IMINE; N SULFONYLIMINE DERIVATIVE; PHOSPHINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CATALYST; CHEMICAL STRUCTURE; CHIRALITY; COMPLEX FORMATION; DIELS ALDER REACTION; ENANTIOSELECTIVITY; REACTION ANALYSIS;

EID: 0347717646     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja038494y     Document Type: Article

References (23)

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17. See Supporting Information for detailed X-ray data.
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21. For instance, the tosylamides 5a and 5g, having an aryl and an alkenyl group at C-2 respectively, afforded the chiral 4-oxopiperidines 8a and 8g in satisfactory yields (58-64%, unoptimized) upon treatment with Zn/ AcOH at room temperature. For the deprotection of sulfonamides, see: (a) Greene, T. W.; Wuts, P. G. M. Protective Groups in Organic Synthesis, 3rd ed; John Wiley & Sons: New York, 1999; p 603-615. For the selective deprotection of p-nitrophenyl sulfonamides, see:
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23. 2 provided enantiomerically pure compounds (>99.5% ee, 60-70% yield).